Patents Assigned to ABCHECK s.r.o.
  • Method for mass humanization of rabbit antibodies
    Patent number: 11685773
    Abstract: The present invention relates to a method for producing a population of 20 or more nucleic acids, each encoding at least one protein comprising at least one immunoglobulin variable domain having a rabbit-derived CDR3 amino acid sequence embedded in essentially human framework sequences, as well as to a population of nucleic acids and a population of proteins relates thereto and uses thereof.
    Type: Grant
    Filed: April 29, 2016
    Date of Patent: June 27, 2023
    Assignees: ABCHECK s.r.o., CHARLES RIVER LABORATORIES, INC.
    Inventors: Jacob E. Gunn Glanville, Vera Molkenthin, Remko Albert Griep, Ahmad Trad, Peter Milovnik, Volker Lang