Patents Assigned to Absorber AB
  • Blood group antigens of different types for diagnostic and therapeutic applications
    Patent number: 8404456
    Abstract: The present invention provides compositions and methods for treating or preventing antibody mediated graft rejection and blood typing.
    Type: Grant
    Filed: February 28, 2011
    Date of Patent: March 26, 2013
    Assignee: AbSorber AB
    Inventors: Jan Holgersson, Jining Liu, Linda Lindberg, Per Grufman
  • Methods of donor specific crossmatching
    Patent number: 8173372
    Abstract: The detection of endothelial cell antibodies has been proven clinically important for successful organ transplantation. Disclosed are methods of isolating Tie-2+ and CD34? precursor endothelial cells for use in donor-specific crossmatching.
    Type: Grant
    Filed: May 16, 2003
    Date of Patent: May 8, 2012
    Assignee: AbSorber AB
    Inventor: Suchitra Sumitran-Holgersson
  • BLOOD GROUP ANTIGENS OF DIFFERENT TYPES FOR DIAGNOSTIC AND THERAPEUTIC APPLICATIONS
    Publication number: 20110287556
    Abstract: The present invention provides compositions and methods for treating or preventing antibody mediated graft rejection and blood typing.
    Type: Application
    Filed: February 28, 2011
    Publication date: November 24, 2011
    Applicant: AbSorber AB
    Inventors: Jan Holgersson, Jining Liu, Linda Lindberg, Per Grufman
  • Methods of donor specific crossmatching
    Patent number: 8034635
    Abstract: The detection of endothelial cell antibodies has been proven clinically important for successful organ transplantation. Disclosed are methods of isolating endothelial cell antibodies and methods for donor-specific crossmatching.
    Type: Grant
    Filed: December 2, 2008
    Date of Patent: October 11, 2011
    Assignee: AbSorber AB
    Inventor: Suchitra Sumitran Holgersson
  • Blood group antigens of different types for diagnostic and therapeutic applications
    Patent number: 7897328
    Abstract: The present invention provides compositions and methods for treating or preventing antibody mediated graft rejection and blood typing.
    Type: Grant
    Filed: March 23, 2007
    Date of Patent: March 1, 2011
    Assignee: AbSorber AB
    Inventors: Jan Holgersson, Jining Liu, Linda Lindberg, Per Grufman
  • Blood group antigen fusion polypeptides and methods of use thereof
    Patent number: 7355017
    Abstract: The present invention provides compositions and methods for treating or preventing antibody mediated graft rejection.
    Type: Grant
    Filed: July 19, 2002
    Date of Patent: April 8, 2008
    Assignee: Absorber AB
    Inventors: Jonas Lofling, Jan Holgersson
  • Antigenic fusionprotein carrying Gal?1,3Gal epitopes
    Patent number: 6943239
    Abstract: The present invention relates to an antigenic fusionprotein, which carries multiple Gal?1,3Gal epitopes. The fusion protein according to the invention may also be comprised of a heavily glycosylated mucin part, which mediates binding to selectins, such as PSGL-1, and a part, which exhibits immunoglobulin properties, such as the Fc part of IgG. The fusionprotein according to the invention is preferably used as an absorber to prevent a hyperacute rejection of a xenotransplant, such as a pig tissue or organ transplanted into a human patient. In addition, the invention relates to a method for the prevention of hyperacute rejection reaction in a patient who is to receive a xenotransplant.
    Type: Grant
    Filed: March 26, 1998
    Date of Patent: September 13, 2005
    Assignee: Absorber AB
    Inventors: Jan Holgersson, Jining Liu