Patents Assigned to Actium BioSystems, LLC
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Publication number: 20140243733Abstract: The Invasive Agent Treatment System incorporates the pairing of energy fields with nano-particles to cause a thermal effect in the nano-particles, which thermal effect is transmitted into the biological cells of the invasive agent. The energy fields are derived from at least one or a combination of the following: an electric field, a magnetic field, an electromagnetic field (EM), an acoustic field, and an optical field. The Invasive Agent Treatment System provides the necessary coordination among the characteristics of the nano-particles, concentration of nano-particles, duration of treatment, and applied fields to enable the generation of precisely crafted fields and their application in a mode and manner to be effective with a high degree of accuracy.Type: ApplicationFiled: May 6, 2014Publication date: August 28, 2014Applicant: Actium BioSystems, LLCInventors: Daniel B. McKenna, Karl M. Frantz, Andrew C. Updegrave, Martin A. Huisjen
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Patent number: 8757166Abstract: The Invasive Agent Treatment System incorporates the pairing of energy fields with nano-particles to cause a thermal effect in the nano-particles, which thermal effect is transmitted into the biological cells of the invasive agent. The energy fields are derived from at least one or a combination of the following: an electric field, a magnetic field, an electromagnetic field (EM), an acoustic field, and an optical field. The Invasive Agent Treatment System provides the necessary coordination among the characteristics of the nano-particles, concentration of nano-particles, duration of treatment, and applied fields to enable the generation of precisely crafted fields and their application in a mode and manner to be effective with a high degree of accuracy.Type: GrantFiled: January 24, 2011Date of Patent: June 24, 2014Assignee: Actium BioSystems, LLCInventors: Daniel Bernard McKenna, Karl Michael Frantz, Andrew Curtis Updegrave, Martin Albert Huisjen
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Publication number: 20130053619Abstract: The Body Cavity Cancer Treatment System achieves extremely uniform temperatures inside the tissue of the body cavity thereby realizing optimal efficacy in enhancing operation of the chemotherapy agent while avoiding harm or pain to the patient. This is accomplished by the inclusion of “target particles”, such as nano-particles, into the body cavity along with the chemotherapy agent to enable the use of an externally generated energy field to cause heating of the chemotherapy agent and the surrounding tissue of the body cavity by the activation of the nano-particles. The proper selection of the applied energy field enables precise control of the heat generated by the movement of the nano-particles.Type: ApplicationFiled: August 21, 2012Publication date: February 28, 2013Applicant: Actium BioSystems, LLCInventors: Danie B. McKenna, Robert J. Tondu, Alireza Mashal, Karl M. Frantz, Martin A. Huisjen
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Publication number: 20130053620Abstract: The Body Cavity Cancer Treatment Apparatus generates the magnetic field for use in a combined “Low Temperature Hyperthermia” and ionizing radiation and/or chemotherapy cancer treatment protocol. Unlike other competing systems, the Body Cavity Cancer Treatment Apparatus does not directly kill or ablate the cancer cells with killing temperatures rather, the Body Cavity Cancer Treatment Apparatus stresses the cancer and cancer stem cells by keeping them at a nominal 42° Celsius for some period of time via the heating of nano-particles that have been infused into the bladder, using the generated magnetic field.Type: ApplicationFiled: August 21, 2012Publication date: February 28, 2013Applicant: Actium BioSystems, LLCInventors: Michael Edward Susedik, Karl Michael Frantz, Daniel Bernard McKenna, Martin Albert Huisjen, Carolyn Perry Adams
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Publication number: 20120190910Abstract: The Invasive Agent Treatment System incorporates the pairing of energy fields with nano-particles to cause a thermal effect in the nano-particles, which thermal effect is transmitted into the biological cells of the invasive agent. The energy fields are derived from at least one or a combination of the following: an electric field, a magnetic field, an electromagnetic field (EM), an acoustic field, and an optical field. The Invasive Agent Treatment System provides the necessary coordination among the characteristics of the nano-particles, concentration of nano-particles, duration of treatment, and applied fields to enable the generation of precisely crafted fields and their application in a mode and manner to be effective with a high degree of accuracy.Type: ApplicationFiled: January 24, 2011Publication date: July 26, 2012Applicant: Actium BioSystems, LLCInventors: Daniel B. McKenna, Karl M. Frantz, Andrew C. Updegrave, Martin A. Huisjen
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Publication number: 20120190912Abstract: The Energy Field and Target Correlation System automatically correlates the characteristics of target particles and a living organism to compute the characteristics of an energy field that is applied to a living organism to activate the target particles which are bound to or consumed or taken up by invasive agents in the living organism to produce detectable effects which can be used to image and treat the invasive agents. The energy field must be crafted to properly control the response and localize the extent of the illumination. The System automatically selects a set of energy field characteristics, including: field type, frequency, field strength, duration, field modulation, repetition frequency, beam size, and focal point. The determined energy field characteristics then are used to activate field generators to generate the desired energy field.Type: ApplicationFiled: January 24, 2011Publication date: July 26, 2012Applicant: Actium BioSystems, LLCInventors: Daniel B. McKenna, Karl M. Frantz, Marvin A. Ross, Andrew C. Updegrave, Michael E. Susedik
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Publication number: 20120191148Abstract: The Energy Field and Target Correlation System automatically correlates the characteristics of target particles and a living organism to compute the characteristics of an energy field that is applied to a living organism to activate the target particles which are bound to or consumed by invasive agents in the living organism to produce detectable effects which can be used to treat the invasive agents. The energy field must be crafted to properly control the response and localize the extent of the illumination. The System automatically selects a set of energy field characteristics, including: field type, frequency, field strength, duration, field modulation, repetition frequency, beam size, and focal point. The determined energy field characteristics then are used to activate field generators to generate the desired energy field.Type: ApplicationFiled: January 24, 2011Publication date: July 26, 2012Applicant: Actium BioSystems, LLCInventors: Daniel B. McKenna, Karl M. Frantz, Marvin A. Ross, Andrew C. Updegrave, Michael E. Susedik
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Publication number: 20120190911Abstract: The Low Temperature Hyperthermia System illuminates nano-particles, which are implanted in a living organism at the locus of the cancer or into the cancer cells, with a precisely determined energy field. This energy field ensures that the optimal cancer cell and cancer stem cell destruction temperature of 42° C. is not exceeded in the tissue, which minimizes the release of Heat Shock Proteins and cancer stem cells. The Low Temperature Hyperthermia System uses specially designed nano-particles that exhibit a specific temperature rise in a given illumination energy field and then have no further temperature rise even if the applied illumination energy field increases beyond the optimal level. Alternatively, the nano-particles exhibit a tightly controlled temperature rise based on a pre-determined illumination energy field strength. This innovative approach can also use radiation and/or chemotherapy in conjunction with the nano-particle illumination to kill the majority of the cancer cells.Type: ApplicationFiled: January 24, 2011Publication date: July 26, 2012Applicant: Actium BioSystems, LLCInventors: Daniel B. McKenna, Robert J. Tondu
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Publication number: 20120190978Abstract: The Energy Field and Target Correlation System automatically correlates the characteristics of target particles and a living organism to compute the characteristics of an energy field that is applied to a living organism to activate the target particles which are bound to or consumed or taken up by invasive agents in the living organism to produce detectable effects which can be used to diagnose the presence and locus of the invasive agents. The energy field must be crafted to properly control the response and localize the extent of the illumination. The System automatically selects a set of energy field characteristics, including: field type, frequency, field strength, duration, field modulation, repetition frequency, beam size, and focal point. The determined energy field characteristics then are used to activate field generators to generate the desired energy field. A multi-dimensional image is produced identifying the spatial extent of the invasive agent.Type: ApplicationFiled: January 24, 2011Publication date: July 26, 2012Applicant: Actium BioSystems, LLCInventors: Daniel B. McKenna, Karl M. Frantz
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Publication number: 20120190979Abstract: The Energy Field and Target Correlation System automatically correlates the characteristics of target particles and a living organism to compute the characteristics of an energy field that is applied to a living organism to activate the target particles which are bound to or consumed or taken up by invasive agents in the living organism to produce detectable effects which can be used to treat the invasive agents. The energy field must be crafted to properly control the response and localize the extent of the illumination. The System automatically selects a set of energy field characteristics, including: field type, frequency, field strength, duration, field modulation, repetition frequency, beam size, and focal point. The determined energy field characteristics then are used to activate field generators to generate the desired energy field.Type: ApplicationFiled: January 24, 2011Publication date: July 26, 2012Applicant: Actium BioSystems, LLCInventors: Daniel B. McKenna, Karl M. Frantz