Abstract: An intelligent vital microscopy, IVM, device is described. The IVM device includes: a receiver configured to receive at least one IVM image of a human microcirculation, MC, of an organ surface; a learning processor coupled to the receiver and configured to: process the at least one IVM image and extract at least one MC variable therefrom, and identify from the extracted at least one MC variable of the at least one IVM image at least one of: an underlying cause for an observed abnormality, an intervention, a disease state, a disease diagnosis, a medical state of the human; a presence of a pathogen; and an output coupled to the learning processor and configured to output the identification.