Patents Assigned to Aduro GVAX Inc.
  • Cryoprotected, frozen recombinant cancer cells
    Patent number: 9848598
    Abstract: This invention provides compositions and methods for cryoprotection of recombinant live cancer cells. Specifically, an improved cryoprotective medium is provided which includes a hydroxyethyl starch and/or derivative thereof alone or in combination with either DMSO or glycerol.
    Type: Grant
    Filed: August 12, 2016
    Date of Patent: December 26, 2017
    Assignee: ADURO GVAX INC.
    Inventors: David Frey, Andy Lin, Gautum Banik
  • Methods and compositions for treating prostate cancer or inducing a humoral immune response against prostate cancer
    Patent number: 9669081
    Abstract: The present invention relates to prostate cancer markers, compositions comprising such markers, and methods of using such markers to induce or increase an immune response against prostate cancer. An immune response against the markers correlates with an immune response, in particular a humoral immune response, against prostate cancer cells which immune response is preferably associated with prophylaxis of prostate cancer, treatment of prostate cancer, and/or amelioration of at least one symptom associated with prostate cancer.
    Type: Grant
    Filed: September 19, 2014
    Date of Patent: June 6, 2017
    Assignee: ADURO GVAX, INC.
    Inventors: Karin Jooss, Thomas Harding, Minh Nguyen, Kathryn E. Koprivnikar
  • Directly injectable formulations which provide enhanced cryoprotection of cell products
    Patent number: 9433204
    Abstract: This invention provides compositions and methods for cryoprotection of recombinant live cancer cells. Specifically, an improved cryoprotective medium is provided which includes a hydroxyethyl starch and/or derivative thereof alone or in combination with either DMSO or glycerol.
    Type: Grant
    Filed: March 4, 2011
    Date of Patent: September 6, 2016
    Assignee: ADURO GVAX INC.
    Inventors: David Frey, Andy Lin, Gautum Banik
  • Methods and compositions for treating prostate cancer or inducing a humoral immune response against prostate cancer
    Patent number: 8840881
    Abstract: The present invention relates to prostate cancer markers, compositions comprising such markers, and methods of using such markers to induce or increase an immune response against prostate cancer. An immune response against the markers correlates with an immune response, in particular a humoral immune response, against prostate cancer cells which immune response is preferably associated with prophylaxis of prostate cancer, treatment of prostate cancer, and/or amelioration of at least one symptom associated with prostate cancer.
    Type: Grant
    Filed: August 24, 2009
    Date of Patent: September 23, 2014
    Assignee: Aduro Gvax Inc.
    Inventors: Karin Jooss, Thomas Harding, Minh Nguyen, Kathryn E. Koprivnikar
  • PD-1 ANTIBODIES IN COMBINATION WITH A CYTOKINE-SECRETING CELL AND METHODS OF USE THEREOF
    Publication number: 20140271684
    Abstract: The present invention relates to a method of enhancing the anti-tumor response in a mammal. More particularly, the invention is concerned with combinations comprising a cytokine-secreting cell and an anti-PD-1 antibody, and methods of administering the combination for enhanced immune response to tumor cells in a patient with a cancer.
    Type: Application
    Filed: November 12, 2013
    Publication date: September 18, 2014
    Applicants: Medarex, Inc., ADURO GVAX INC.
    Inventors: Betty LI, Karin JOOSS, Alan J. KORMAN
  • PS-1 antibodies in combination with a cytokine-secreting cell and methods of use thereof
    Patent number: 8580247
    Abstract: The present invention relates to a method of enhancing the anti-tumor response in a mammal. More particularly, the invention is concerned with combinations comprising a cytokine-secreting cell and an anti-PD-1 antibody, and methods of administering the combination for enhanced immune response to tumor cells in a patient with a cancer.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: November 12, 2013
    Assignees: Aduro GVAX Inc., Medarex, Inc.
    Inventors: Betty Li, Karin Jooss, Alan J. Korman