Patents Assigned to Advalytix AG
  • Patent number: 7459304
    Abstract: The invention relates to a method for the analysis of macromolecules using a microarray on which a plurality of first at least partly different macromolecules are located in a known arrangement, wherein the microarray is arranged on a solid surface on which a region is defined whose wetting properties differ from the surrounding solid surface such that a liquid with a plurality of second macromolecules preferably stays thereon, the liquid with the second macromolecules is brought onto the solid surface and at least partly removed and the second macromolecules remaining after the removal process are detected in order to determine from the position which of the first macromolecules have formed a bond with second macromolecules. The invention further relates to a method wherein a surface wave is launched to the liquid to distribute and/or thoroughly mix the liquid on the microarray.
    Type: Grant
    Filed: December 19, 2001
    Date of Patent: December 2, 2008
    Assignee: Advalytix AG
    Inventor: Christoph Gauer
  • Publication number: 20080225634
    Abstract: A stirring vessel is for stirring a retained liquid by an acoustic wave, and includes at least one acoustic wave generating unit that emits an acoustic wave into the liquid and is provided as deviated on the stirring vessel.
    Type: Application
    Filed: April 7, 2008
    Publication date: September 18, 2008
    Applicants: OLYMPUS CORPORATION, ADVALYTIX AG.
    Inventor: Miyuki MURAKAMI
  • Publication number: 20080186799
    Abstract: A method or device for integrated dosing and intermixing of small amounts of liquid, has a first liquid conveyed into or onto a first reservoir (3). A second reservoir (1) is entirely filled with a second liquid. The first and second liquids are brought into contact with each other via at least one joining duct structure (5) which has at least one area provided with a smaller cross section than the reservoirs (1,3) in the viewing direction of the connecting line between the two reservoirs (1,3). A laminar flow pattern is created along at least one portion of the joining duct structure (5), with the liquids thoroughly mixed in the second reservoir (1).
    Type: Application
    Filed: December 16, 2005
    Publication date: August 7, 2008
    Applicant: Advalytix AG
    Inventor: Christoph Gauer
  • Publication number: 20070264161
    Abstract: The invention relates to a method for generating motion in a thin liquid film on a substrate, in particular in a capillary gap, in which at least one ultrasound wave is sent right through the substrate in the direction of the liquid film, and a device for carrying out the inventive method.
    Type: Application
    Filed: January 27, 2004
    Publication date: November 15, 2007
    Applicant: Advalytix AG
    Inventor: Andreas Rathgeber
  • Patent number: 7198813
    Abstract: The invention relates to methods and devices for manipulation of small amounts of liquid on surfaces, preferably on chip surfaces. According to the present invention, a quantity of liquid held together by its surface tension is applied on an area of a surface with at least one intermediate region, which borders at least in one lateral direction on a guide strip. According to the present invention, the guide strips have different surface characteristics relative to the intermediate region, such that they are more strongly wetted by a liquid, or the intermediate region is raised relative to the guide strips, whereby the height of the step is small relative to the height of the quantity of liquid.
    Type: Grant
    Filed: April 24, 2002
    Date of Patent: April 3, 2007
    Assignee: Advalytix AG
    Inventor: Achim Wixforth
  • Patent number: 6777245
    Abstract: A process for specific and direct manipulation of small quantities of matter on solid-body surfaces, in which surface waves are generated with at least one surface-wave generator and the impulse of one or more surface waves is made to interact with at least one quantity of matter, in order to cause a movement in a desired direction.
    Type: Grant
    Filed: January 23, 2001
    Date of Patent: August 17, 2004
    Assignee: Advalytix AG
    Inventor: Achim Wixforth