Abstract: A process for generating transgenic animals using recombinant lentiviruses. The process comprises injecting recombinant lentiviruses into the interstituim of the testis of a male to produce mature spermatozoa within a few days. The male with transgene expressing lentivirus is mated with a female, forming a progeny carrying the transgene.
Type:
Grant
Filed:
January 11, 2011
Date of Patent:
February 12, 2013
Assignees:
Advanced Centre for Treatment, Research & Education in Cancer (ACTREC), Department of Biotechnology
Inventors:
Sorab N. Dalal, Lalit Sehgal, Nileema Khapare, Rahul Thorat
Abstract: A process for generating transgenic animals using recombinant lentiviruses. The process comprises injecting recombinant lentiviruses into the interstituim of the testis of a male to produce mature spermatozoa within a few days. The male with transgene expressing lentivirus is mated with a female, forming a progeny carrying the transgene.
Type:
Application
Filed:
January 11, 2011
Publication date:
April 19, 2012
Applicants:
Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), DEPARTMENT OF BIOTECHNOLOGY
Inventors:
Sorab N. Dalal, Lalit Sehgal, Nileema Khapare, Rahul Thorat