Patents Assigned to Agamatrix, Inc.
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Publication number: 20140231252Abstract: A portable combination for measuring a glucose concentration value in a sample has a portable glucose meter (GM) having a test strip port for receiving a disposable electrochemical test strip, means for calculating a glucose concentration value in a sample applied to a test strip received in the test strip port, and optionally a rechargeable GM battery. Next the combination has a portable rechargeable supplemental battery pack (SBP). The combination also has a web enabled portable device (WEPD) having a rechargeable WEPD battery and a wireless connection to the Internet. The GM, the SBP, and the WEPD are electrically coupled to allow power transfer between the GM, the SBP, and the WEPD. The GM and the WEPD are communicatively coupled to allow for data transfer between the GM and the WEPD. The GM and SBP are detachable from and reattachable to the WEPD to form the portable combination. Lastly the combination has means for managing battery operations of the combination.Type: ApplicationFiled: April 30, 2014Publication date: August 21, 2014Applicant: AgaMatrix, Inc.Inventor: Anoop Rao
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Patent number: 8758594Abstract: The presence of oxygen or red blood cells in a sample applied to an electrochemical test strip that makes use of a reduced mediator is corrected for by an additive correction factor that is determined as a function of the temperature of the sample and a measurement that reflects the oxygen carrying capacity of the sample. The measured oxygen carrying capacity can also be used to determine hematocrit and to distinguish between blood samples and control solutions applied to a test strip.Type: GrantFiled: December 21, 2012Date of Patent: June 24, 2014Assignee: AgaMatrix, Inc.Inventors: Ian Harding, Richard Williams, Sridhar Iyengar
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Patent number: 8758582Abstract: An electrochemical test strip is formed from a first insulating substrate layer, a second substrate layer, and an intervening insulating spacer layer. An opening in the insulating spacer layer defines a test cell which is in contact with the inner surface of the first substrate on one side and the inner surface of the second substrate on the other side. The size of the test cell is determined by the area of substrate exposed and the thickness of the spacer layer. Working and counter electrodes appropriate for the analyte to be detected are disposed on the first insulating substrate in a location within the test cell. The working and counter electrodes are associated with conductive leads that allow The second substrate is conductive at least in a region facing the working and counter electrodes. No functional connection of this conductive surface of the second substrate to the meter is required.Type: GrantFiled: July 21, 2008Date of Patent: June 24, 2014Assignee: AgaMatrix, Inc.Inventors: Ian Harding, Sridhar Iyengar
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Publication number: 20140151222Abstract: The ability to switch at will between amperometric measurements and potentiometric measurements provides great flexibility in performing analyses of unknowns. Apparatus and methods can provide such switching to collect data from an electrochemical cell. The cell may contain a reagent disposed to measure glucose in human blood.Type: ApplicationFiled: November 25, 2013Publication date: June 5, 2014Applicant: AgaMatrix, Inc.Inventors: Ian Harding, Sridhar G. Iyengar, Baoguo Wei, Steven Diamond, Martin Forest
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Publication number: 20140116894Abstract: A device for measuring blood coagulation time is formed from a first substrate; a second substrate; a spacer layer disposed between the first and second substrates, said spacer layer having an opening formed therein defining a sample receiving chamber, a vented sink chamber, and an elongated reservoir forming a conduit for liquid movement between the sample receiving chamber and the sink chamber; a first electrode disposed on the first substrate, said first electrode being exposed in the reservoir portion through a first opening in the spacer layer; and a second electrode disposed on the second substrate, said second electrode being exposed in the reservoir portion through a second opening in the spacer layer. The device of the invention is used in combination with an apparatus that is connected to the first and second electrodes for measuring current flow between the first and second electrodes.Type: ApplicationFiled: November 27, 2013Publication date: May 1, 2014Applicant: AgaMatrix, Inc.Inventors: Ian Harding, Sridhar G. Iyengar, Ha Nguyen, Richard Williams, Anoop Rao
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Publication number: 20140083870Abstract: A method is provided for determining analyte concentrations, for example glucose concentrations, that utilizes a dynamic determination of the appropriate time for making a glucose measurement, for example when a current versus time curve substantially conforms to a Cottrell decay, or when the current is established in a plateau region. Dynamic determination of the time to take the measurement allows each strip to operate in the shortest appropriate time frame, thereby avoiding using an average measurement time that may be longer than necessary for some strips and too short for others.Type: ApplicationFiled: November 25, 2013Publication date: March 27, 2014Applicant: AgaMatrix, Inc.Inventors: Steven Diamond, Ian Harding, Sridhar G. Iyentar, Baguo Wei
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Publication number: 20140048425Abstract: The presence of a select analyte in the sample is evaluated in an an electrochemical system using a conduction cell-type apparatus. A potential or current is generated between the two electrodes of the cell sufficient to bring about oxidation or reduction of the analyte or of a mediator in an analyte-detection redox system, thereby forming a chemical potential gradient of the analyte or mediator between the two electrodes After the gradient is established, the applied potential or current is discontinued and an analyte-independent signal is obtained from the relaxation of the chemical potential gradient. The analyte-independent signal is used to correct the analyte-dependent signal obtained during application of the potential or current.Type: ApplicationFiled: August 19, 2013Publication date: February 20, 2014Applicant: AgaMatrix, Inc.Inventors: Sridhar G. Iyengar, Ian Harding
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Patent number: 8623280Abstract: A device for measuring blood coagulation time is formed from a first substrate; a second substrate; a spacer layer disposed between the first and second substrates, said spacer layer having an opening formed therein defining a sample receiving chamber, a vented sink chamber, and an elongated reservoir forming a conduit for liquid movement between the sample receiving chamber and the sink chamber; a first electrode disposed on the first substrate, said first electrode being exposed in the reservoir portion through a first opening in the spacer layer; and a second electrode disposed on the second substrate, said second electrode being exposed in the reservoir portion through a second opening in the spacer layer. The device of the invention is used in combination with an apparatus that is connected to the first and second electrodes for measuring current flow between the first and second electrodes.Type: GrantFiled: November 16, 2010Date of Patent: January 7, 2014Assignee: AgaMatrix, Inc.Inventors: Ian Harding, Sridhar G. Iyengar, Ha Nguyen, Richard Williams
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Publication number: 20140001046Abstract: The ability to switch at will between amperometric measurements and potentiometric measurements provides great flexibility in performing analyses of unknowns. Apparatus and methods can provide such switching to collect data from an electrochemical cell. The cell may contain a reagent disposed to measure glucose in human blood.Type: ApplicationFiled: March 8, 2013Publication date: January 2, 2014Applicant: AgaMatrix, Inc.Inventors: Ian Harding, Sridhar G. Iyengar, Baoguo Wei, Steven Diamond, Martin Forest
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Publication number: 20140001045Abstract: An electrochemical test device is provided having a base layer with a first electrode thereon and a top layer with a second electrode thereon. The two electrodes are separated by a spacer layer having an opening therein, such that a sample-receiving space is defined with one electrode on the top surface, the other electrodes on the bottom surface and side walls formed from edges of the opening in the spacer. Reagents for performing the electrochemical reaction are deposited on one of the electrodes and on the side walls of the sample-receiving space.Type: ApplicationFiled: August 27, 2013Publication date: January 2, 2014Applicant: AgaMatrix, Inc.Inventor: Ian Harding
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Patent number: 8617365Abstract: An electrochemical test device is provided having a base layer with a first electrode thereon and a top layer with a second electrode thereon. The two electrodes are separated by a spacer layer having an opening therein, such that a sample-receiving space is defined with one electrode on the top surface, the other electrodes on the bottom surface and side walls formed from edges of the opening in the spacer. Reagents for performing the electrochemical reaction are deposited on one of the electrodes and on the side walls of the sample-receiving space.Type: GrantFiled: May 21, 2005Date of Patent: December 31, 2013Assignee: AgaMatrix, Inc.Inventor: Ian Harding
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Patent number: 8591815Abstract: The ability to switch at will between amperometric measurements and potentiometric measurements provides great flexibility in performing analysis of unknowns. Apparatus and methods can provide such switching to collect data from an electrochemical cell. The cell may contain a reagent disposed to measure glucose in human blood.Type: GrantFiled: May 16, 2011Date of Patent: November 26, 2013Assignee: AgaMatrix, Inc.Inventors: Ian Harding, Sridhar G. Iyengar, Baoguo Wei, Steven Diamond, Martin Forest
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Patent number: 8591722Abstract: A method is provided for determining analyte concentrations, for example glucose concentrations, that utilizes a dynamic determination of the appropriate time for making a glucose measurement, for example when a current versus time curve substantially conforms to a Cottrell decay, or when the current is established in a plateau region. Dynamic determination of the time to take the measurement allows each strip to operate in the shortest appropriate time frame, thereby avoiding using an average measurement time that may be longer than necessary for some strips and too short for others.Type: GrantFiled: August 9, 2011Date of Patent: November 26, 2013Assignee: AgaMatrix, Inc.Inventors: Steven Diamond, Ian Harding, Sridhar G. Iyengar, Baoguo Wei
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Publication number: 20130306492Abstract: A method for monitoring a select analyte in a sample in an electrochemical system. The method includes applying to the electrochemical system a time-varying potential superimposed on a DC potential to generate a signal; and discerning from the signal a contribution from the select analyte by resolving an estimation equation based on a Faradaic signal component and a nonfaradaic signal component.Type: ApplicationFiled: October 18, 2012Publication date: November 21, 2013Applicant: AGAMATRIX, INC.Inventor: AgaMatrix, Inc.
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Patent number: 8512546Abstract: The presence of a select analyte such as glucose in the sample is evaluated in an electrochemical system using a conduction cell-type apparatus. A potential or current is generated between the two electrodes of the cell sufficient to bring about oxidation or reduction of the analyte or of a mediator in an analyte-detection redox system, thereby forming a chemical potential gradient of the analyte or mediator between the two electrodes after the gradient is established, the applied potential or current is discontinued and an analyte-independent signal is obtained from the relaxation of the chemical potential gradient. The analyte-independent signal is used to correct the analyte-dependent signal obtained during application of the potential or current.Type: GrantFiled: January 24, 2012Date of Patent: August 20, 2013Assignee: AgaMatrix, Inc.Inventors: Sridhar G. Iyengar, Ian Harding
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Publication number: 20130175184Abstract: A test meter for receiving a test strip comprises: (a) a housing; (b) electronic circuitry disposed within the housing and (c) a strip port connector connected to the electronic circuitry and extending to an opening in the housing, said strip port connector connecting the electronic circuitry with a received test strip. The strip port connector contains a pair of top and bottom contacts, said top and bottom contacts having a proximal end and a distal end and a central contact portion, the top and bottom contacts of the pair are transversely aligned with one another; and the distal ends of the top and bottom contacts are separated or separable from one another by insertion of a test strip between the opposed contacts. The contacts and the meter are adapted to permit detection of faulty contacts and/or coding associated with an inserted test strip.Type: ApplicationFiled: September 16, 2011Publication date: July 11, 2013Applicant: AGAMATRIX, INC.Inventors: Sridhar Iyengar, Charles Boiteau, Martin Forest, Colin Butters
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Publication number: 20130146478Abstract: A test strip with an incorporated optical waveguide and deflectors punched through the optical waveguide allows light to exit through a layer of the test strip and be detected by a photo detector. Using light and a photodetector, these uniquely coded strips are identified. The waveguide can be constructed by sandwiching two layers of the test strip around a light transmissible layer. This configuration allows light to be transmitted through the test strip and out the other end, as well as allowing some light to escape the deflector. This light is detected by a photodetector mounted in the analyte test meter. The deflectors may be placed in patterns such that detection of this light indicates certain characteristics of the strip, such as non-counterfeit, regional identification, type of analyte tested, and coding information.Type: ApplicationFiled: June 30, 2011Publication date: June 13, 2013Applicant: AgaMatrix, INC.Inventors: Sridhar Iyengar, Ian Harding, Charles Boiteau, Colin Butters
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Publication number: 20130118921Abstract: The presence of oxygen or red blood cells in a sample applied to an electrochemical test strip that makes use of a reduced mediator is corrected for by an additive correction factor that is determined as a function of the temperature of the sample and a measurement that reflects the oxygen carrying capacity of the sample. The measured oxygen carrying capacity can also be used to determine hematocrit and to distinguish between blood samples and control solutions applied to a test strip.Type: ApplicationFiled: December 21, 2012Publication date: May 16, 2013Applicant: AGAMATRIX, INC.Inventor: AGAMATRIX, INC.
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Publication number: 20130026050Abstract: A dry reagent composition that includes an active redox enzyme that oxidizes an analyte as a specific substrate to produce an inactive reduced form of the enzyme; and a salt of ferricyanide provides improved performance in electrochemical test strips such as those used for detection of glucose. The salt of ferricyanide consists of ferricyanide and positively-charged counter ions, and the positively charged counter ions are selected such that the salt of ferricyanide is soluble in water, and such that the salt of ferricyanide or the crystalline phase of the salt of ferricyanide has a solubility in water and/or a lower E0eff at a concentration of 100 mM than potassium ferricyanide. For example, the salt of ferricyanide may be tetramethylammonium ferricyanide.Type: ApplicationFiled: July 25, 2012Publication date: January 31, 2013Applicant: AGAMATRIX, INC.Inventors: Ian Harding, Mary Y. Lee, Sandie Tan
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Patent number: 8361307Abstract: The presence of oxygen or red blood cells in a sample applied to an electrochemical test strip that makes use of a reduced mediator is corrected for by an additive correction factor that is determined as a function of the temperature of the sample and a measurement that reflects the oxygen carrying capacity of the sample. The measured oxygen carrying capacity can also be used to determine hematocrit and to distinguish between blood samples and control solutions applied to a test strip.Type: GrantFiled: July 27, 2011Date of Patent: January 29, 2013Assignee: AgaMatrix, Inc.Inventors: Ian Harding, Richard Williams, Sridhar Iyengar