Abstract: A water pressure relief device includes a sample removal port to permit samples of water to be removed from the device. The device has an insert placed in a central chamber disposed generally above the sample removal port. The user inserts an implement such as a syringe into the sample removal port. The tip of the syringe pushes the insert upwards against a pressure relief member, permitting fluid to flow into the base of the device in the vicinity of the sample removal port. The implement then removes or catches the fluid and withdraws the fluid from the pressure relief device.

Abstract: A dialysis machine is disclosed that incorporates a water treatment module, a dialysate preparation module having a dialysate circuit, and an extracorporeal circuit including a dialyzer and arterial and venous blood lines that connect to the patient. The machine accomplishes on-line disinfection of all the fluid circuits of the machine, including the water treatment module, the dialysate preparation module and extracorporeal circuit, the arterial and venous lines, and the dialyzer, by circulating water heated to a high level disinfection temperature (e.g., 80 degrees C.) through the fluid passages of the machine for a sufficient time (such as an hour) to achieve high level disinfection. After the dialysis session is ended, the patient connects the arterial and venous lines to ports in a disinfection manifold that places the arterial and venous lines into fluid communication with the heated water. Thereafter, the machine is ready to disinfect the fluid circuits including the extracorporeal circuit.