Abstract: The present invention provides a sterile collection package and methods for sample procurement and manipulation including microbial and forensic testing. The collection package comprises a tissue or sample collection container with a sealable opening, at least one drain container, and at least one tubing set that connects the tissue or sample collection container and the drain container, the tubing set further optionally comprising a sampling hub for withdrawing sample fluid for microbial and forensic testing. Samples, such as donated tissues, diseased tissues and article and tissues for forensic analysis are mixed with a sampling solution in the collection container and aliquots of the sampling solution are withdrawn through the sampling hub for microbial and/or forensic testing.