Patents Assigned to Albany Medical College of Union University
  • Patent number: 4921808
    Abstract: The present disclosure relates to an improved method based on hormone-receptor binding for the determination of follicle stimulating hormone and to improved reagents useful for the determination of follicle stimulating hormone in a hormone-receptor binding assay.
    Type: Grant
    Filed: June 25, 1986
    Date of Patent: May 1, 1990
    Assignee: The Albany Medical College of Union University
    Inventors: Alan L. Schneyer, Patrick M. Sluss, Bosukonda Dattatreyamurty, Leo E. Reichert, Jr.
  • Patent number: 4871488
    Abstract: The present disclosure relates to novel liposome compositions and methods for their preparation. Utilization of the present invention provides an efficient reconstitution of membrane proteins into large (0.1 to 2 micron diameter) phospholipid vesicles with a large, internal aqueous space. The method has been exemplified with the use of glycoproteins of influenza (A/PR8/34) and Sendai (parainfluenza type I) viruses. The method comprises (A) extracting out the desired membrane protein from a source biological material with an extraction buffer comprising a detergent; (B) mixing the extract with a phospholipid solution and deriving a cochleate intermediate; and (C) forming large phospholipid vesicles with integrated membrane protein in a biologically active state.
    Type: Grant
    Filed: April 13, 1987
    Date of Patent: October 3, 1989
    Assignee: Albany Medical College of Union University
    Inventors: Raphael J. Mannino, Susan G. Fogerite