Abstract: An antibody or Fab fragment, wherein at least one amino group of the N-terminal amino acid of the light chain and/or of the N-terminal amino acid of the heavy chain is bound by an amidic bond to a molecule comprising a fluorophore group A, wherein said bond constitutes at least 70% of the total binding of said molecule to said antibody or Fab.
Type:
Grant
Filed:
June 26, 2018
Date of Patent:
January 2, 2024
Assignee:
Alda S.r.l.
Inventors:
Alberto Luini, Vincenzo Manuel Marzullo, Giuseppe Palumbo, Federica Liccardo
Abstract: An antibody or Fab fragment, wherein at least one amino group of the N-terminal amino acid of the light chain and/or of the N-terminal amino acid of the heavy chain is bound by an amidic bond to a molecule comprising a fluorophore group A, wherein said bond constitutes at least 70% of the total binding of said molecule to said antibody or Fab.
Type:
Application
Filed:
June 26, 2018
Publication date:
May 7, 2020
Applicant:
Alda S.r.l.
Inventors:
Alberto LUINI, Vincenzo Manuel MARZULLO, Giuseppe PALUMBO, Federica LICCARDO