Patents Assigned to Allena Pharmaceuticals, Inc.
  • Crystallized oxalate decarboxylase and methods of use
    Patent number: 11208700
    Abstract: Pharmaceutical compositions comprising spray-dried oxalate decarboxylase crystals are disclosed. Methods to treat a disorder associated with elevated oxalate concentration using compositions comprising spray-dried oxalate decarboxylase crystals are also disclosed.
    Type: Grant
    Filed: January 14, 2020
    Date of Patent: December 28, 2021
    Assignee: Allena Pharmaceuticals, Inc.
    Inventors: Jack Greene, Richard Johnson, Dennis Krushinskie, Bhami Shenoy
  • Compositions, methods, and devices for dialysis
    Patent number: 11077238
    Abstract: Compositions of peritoneal dialysis solutions and metabolizing enzymes, and their uses to treat disorders associated with elevated levels of metabolites are disclosed. Animal models of hyperoxalemia are also disclosed.
    Type: Grant
    Filed: June 6, 2014
    Date of Patent: August 3, 2021
    Assignee: Allena Pharmaceuticals, Inc.
    Inventors: Alexey Margolin, Danica Grujic, Stefan Pierzynowski
  • Recombinant uricase enzyme
    Patent number: 10815461
    Abstract: Disclosed are recombinant mutant Candida utilis uricase enzymes with improved pancreatin stability and/or activity, compositions containing such uricase enzymes, which can be used, among other things, to treat diseases or disorders associated with an elevated amount of uric acid, including, for example, hyperuricemia, hyperuricosuria, and gout.
    Type: Grant
    Filed: November 5, 2019
    Date of Patent: October 27, 2020
    Assignee: Allena Pharmaceuticals, Inc.
    Inventors: Aditi R. Deshpande, Danica Grujic, Sridhar Govindarajan, Mark Welch
  • RECOMBINANT URICASE ENZYME
    Publication number: 20200308534
    Abstract: Disclosed are recombinant mutant Candida utilis uricase enzymes with improved pancreatin stability and/or activity, compositions containing such uricase enzymes, which can be used, among other things, to treat diseases or disorders associated with an elevated amount of uric acid, including, for example, hyperuricemia, hyperuricosuria, and gout.
    Type: Application
    Filed: July 6, 2018
    Publication date: October 1, 2020
    Applicant: Allena Pharmaceuticals, Inc.
    Inventors: Aditi R. DESHPANDE, Danica GRUJIC, Sridhar GOVINDARAJAN, Mark WELCH
  • Crystallized oxalate decarboxylase and methods of use
    Patent number: 10570468
    Abstract: Pharmaceutical compositions comprising spray-dried oxalate decarboxylase crystals are disclosed. Methods to treat a disorder associated with elevated oxalate concentration using compositions comprising spray-dried oxalate decarboxylase crystals are also disclosed.
    Type: Grant
    Filed: February 14, 2019
    Date of Patent: February 25, 2020
    Assignee: Allena Pharmaceuticals, Inc.
    Inventors: Jack Greene, Richard Johnson, Dennis Krushinskie, Bhami Shenoy
  • Crystallized oxalate decarboxylase and methods of use
    Patent number: 10369203
    Abstract: Oxalate decarboxylase crystals, including stabilized crystals, such as cross-linked crystals of oxalate decarboxylase, are disclosed. Methods to treat a disorder associated with elevated oxalate concentration using oxalate decarboxylase crystals are also disclosed. Additionally disclosed are methods of producing protein crystals.
    Type: Grant
    Filed: October 23, 2017
    Date of Patent: August 6, 2019
    Assignee: Allena Pharmaceuticals, Inc.
    Inventors: Bhami C. Shenoy, Teresa G. Cachero, John Shin, Lekai Zhang, Aftab Rashid, Danica Grujic, Reena J. Patel, Margaret Ellen McGrath
  • Crystallized oxalate decarboxylase and methods of use
    Patent number: 10246755
    Abstract: Pharmaceutical compositions comprising spray-dried oxalate decarboxylase crystals are disclosed. Methods to treat a disorder associated with elevated oxalate concentration using compositions comprising spray-dried oxalate decarboxylase crystals are also disclosed.
    Type: Grant
    Filed: June 23, 2017
    Date of Patent: April 2, 2019
    Assignee: Allena Pharmaceuticals, Inc.
    Inventors: Jack Greene, Richard Johnson, Dennis Krushinskie, Bhami Shenoy
  • Crystallized oxalate decarboxylase and methods of use
    Patent number: 9821041
    Abstract: Oxalate decarboxylase crystals, including stabilized crystals, such as cross-linked crystals of oxalate decarboxylase, are disclosed. Methods to treat a disorder associated with elevated oxalate concentration using oxalate decarboxylase crystals are also disclosed. Additionally disclosed are methods of producing protein crystals.
    Type: Grant
    Filed: September 2, 2015
    Date of Patent: November 21, 2017
    Assignee: Allena Pharmaceuticals, Inc.
    Inventors: Bhami C. Shenoy, Teresa G. Cachero, John Shin, Lekai Zhang, Aftab Rashid, Danica Grujic, Reena J. Patel, Margaret Ellen McGrath
  • Crystallized oxalate decarboxylase and methods of use
    Patent number: 9714456
    Abstract: Pharmaceutical compositions comprising spray-dried oxalate decarboxylase crystals are disclosed. Methods to treat a disorder associated with elevated oxalate concentration using compositions comprising spray-dried oxalate decarboxylase crystals are also disclosed.
    Type: Grant
    Filed: January 17, 2014
    Date of Patent: July 25, 2017
    Assignee: Allena Pharmaceuticals, Inc.
    Inventors: Jack Greene, Richard Johnson, Dennis Krushinskie, Bhami Shenoy