Patents Assigned to Allergan Industrie, SAS
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Patent number: 11260015Abstract: Injectable compositions and methods of treating skin can help improve hydration, elasticity and/or texture of the skin. The compositions can be based on crosslinked hyaluronic acid matrices made with low molecular weight hyaluronic acids.Type: GrantFiled: May 18, 2020Date of Patent: March 1, 2022Assignee: Allergan Industrie, SASInventors: Pierre Lebreton, Olivier Guetta
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Patent number: 11224501Abstract: Devices and methods for inserting an implant into skin or other tissue of a patient can include an insertion device that can enclose and support a hyaluronic thread as it is injected into a patient's skin or other tissue. The device can include a cover member, a non-tubular support member, and the thread. The cover member can have a proximal portion, a closed distal portion, and an inner cavity extending from the proximal portion toward the closed distal portion. The thread can be positioned along a longitudinal length of support member, between the support member and the cover member. The non-tubular support member can extend within the inner cavity of the cover member. The cover member can be moveable relative to the support member to expose the thread.Type: GrantFiled: February 28, 2020Date of Patent: January 18, 2022Assignee: Allergan Industrie, SASInventors: Antoine Duc, Bastien Mandaroux
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Patent number: 11173232Abstract: Disclosed herein are soft tissue fillers, for example, dermal and subdermal fillers, based on hyaluronic acids and pharmaceutically acceptable salts thereof. Some of the hyaluronic acid-based compositions can include a therapeutically effective amount of at least one anesthetic agent, for example, lidocaine. Compared to conventional compositions that include lidocaine, some of the hyaluronic acid-based compositions disclosed herein can have an enhanced stability, for example, when subjected to sterilization techniques or when stored for long periods of time. Methods and processes of preparing such compositions are also provided.Type: GrantFiled: July 24, 2019Date of Patent: November 16, 2021Assignee: ALLERGAN INDUSTRIE, SASInventor: Pierre F. Lebreton
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Patent number: 11083684Abstract: The present invention provides highly injectable, long-lasting hyaluronic acid-based hydrogel dermal filler compositions made with a di-amine or multiamine crosslinker in the presence of a carbodiimide coupling agent.Type: GrantFiled: October 30, 2015Date of Patent: August 10, 2021Assignee: ALLERGAN INDUSTRIE, SASInventors: Gabriel N. Njikang, Xiaojie Yu, Futian Liu, Nicholas J. Manesis
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Patent number: 11045490Abstract: An injectable monophase hydrogel is provided that is made of a reaction mixture of hyaluronic acids having different molecular weights.Type: GrantFiled: April 23, 2020Date of Patent: June 29, 2021Assignee: ALLERGAN INDUSTRIE, SASInventor: Pierre F. Lebreton
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Patent number: 11039910Abstract: Devices and methods for inserting an implant into skin or other tissue of a patient can include an insertion device having moveable portions that can retain, move, or otherwise control engagement and injection of a hyaluronic thread. The device can include a tubular member and a handle. The handle can include a body component coupled to the tubular member. The body component can include a passage that extends in communication with the lumen. The handle can further comprise first and second arms coupled to the body component and extending outwardly from the distal portion of the tubular member. Based on the configuration, the first and second arms can be positioned along the passage to change a cross-sectional profile of the passage and permit the device to engage or disengage the thread.Type: GrantFiled: April 11, 2019Date of Patent: June 22, 2021Assignee: Allergan Industrie SASInventors: Antoine Duc, Bastien Mandaroux
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Patent number: 11020512Abstract: Disclosed herein are cohesive soft tissue fillers, for example, dermal and subdermal fillers, based on hyaluronic acids and pharmaceutically acceptable salts thereof. In one aspect, hyaluronic acid-based compositions described herein include a therapeutically effective amount of at least one anesthetic agent, for example, lidocaine. The present hyaluronic acid-based compositions including lidocaine have an enhanced stability and cohesivity, relative to conventional compositions including lidocaine, for example when subjected to sterilization techniques or when stored for long periods of time. Methods and processes of preparing such hyaluronic acid-based compositions are also provided.Type: GrantFiled: November 25, 2019Date of Patent: June 1, 2021Assignee: ALLERGAN INDUSTRIE, SASInventor: Pierre F. Lebreton
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Patent number: 11000626Abstract: Provided are injectable, hyaluronic acid-based dermal filler compositions including conjugated vitamin C derivatives. The compositions provide for extended release of active vitamin C into tissue, promoting collagenesis and other benefits to skin.Type: GrantFiled: March 26, 2018Date of Patent: May 11, 2021Assignee: ALLERGAN INDUSTRIE, SASInventors: Futian Liu, Xiaojie Yu, Jessamine P. Winer-Jones, Nicholas J. Manesis, Hengli Liu, Gabriel Njikang, Athene Wan Chie Chan
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Patent number: 10994049Abstract: The present invention provides highly injectable, long-lasting hyaluronic acid-based hydrogel dermal filler compositions which are particularly advantageous for correction of fine lines in the face.Type: GrantFiled: March 7, 2018Date of Patent: May 4, 2021Assignee: ALLERGAN INDUSTRIE, SASInventors: Gabriel N. Njikang, Xiaojie Yu, Futian Liu, Sumit Paliwal, Nicholas J. Manesis
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Patent number: 10820900Abstract: Devices and methods for inserting an implant into skin or other tissue of a patient can include a hyaluronic thread that is coupled at along distal portion with an insertion device. The insertion device can include a cover member and a piston that can collectively facilitate engagement with or disengagement of the distal portion of the thread with the device. For example, the piston can be positioned within an inner cavity of the cover member, and the distal portion of the thread can be engaged by and/or between the piston and the cover member. The thread can be released by movement of the piston relative to the cover member. Thus, some insertion devices can grasp or engage the distal portion of the thread and “push” the distal portion thread into and through into skin or other tissue of a patient.Type: GrantFiled: January 24, 2017Date of Patent: November 3, 2020Assignee: Allergan Industrie SASInventors: Antoine Duc, Bastien Mandaroux
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Patent number: 10806821Abstract: The disclosure provides hyaluronic acid (HA) gel formulations and methods for treating the appearance of the skin. The formulations contain hyaluronic acid and at least one additional ingredient. Methods for treating lines, wrinkles, fibroblast depletions, and scars with the disclosed composition are provided as well.Type: GrantFiled: March 1, 2019Date of Patent: October 20, 2020Assignee: ALLERGAN INDUSTRIE, SASInventors: Cecile Gousse, Pierre F. Lebreton, Nicholas Prost
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Patent number: 10751484Abstract: A needle injection array can comprise a plurality of needles that are fluidly interconnected via a fluid manifold. The fluid manifold can be configured to direct fluid from a syringe to arrive at tips of the needles approximately simultaneously. The fluid manifold also be configured to provide approximately equal dosage or fluid volume through each of the needles to an injection site.Type: GrantFiled: March 23, 2018Date of Patent: August 25, 2020Assignee: Allergan Industrie, SASInventor: Bastien Mandaroux
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Patent number: 10722444Abstract: The present specification generally relates to an injectable dermal filler composition that includes crosslinked hyaluronic acid-based polymer and an antioxidant.Type: GrantFiled: September 30, 2014Date of Patent: July 28, 2020Assignee: Allergan Industrie, SASInventors: Cécile Gousse, Sébastien Pierre, Pierre F. Lebreton
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Patent number: 10709444Abstract: Devices and methods for inserting an implant into skin or other tissue of a patient can include a hyaluronic thread coupled with an insertion device that can provide a supportive enclosure for the thread as it is injected into a patient's skin or other tissue. The device can include a cover member, a base, and a thread. The cover member can have a proximal portion, a closed distal portion, and an inner cavity extending from the proximal portion toward the closed distal portion. The thread can be positioned within the inner cavity and extend from the base toward the closed distal portion. The base can be removably coupled to the proximal portion of the cover member. In use, the cover member is insertable into a patient and separable from the base to expose the thread.Type: GrantFiled: January 24, 2017Date of Patent: July 14, 2020Assignee: Allergan Industrie SASInventors: Antoine Duc, Bastien Mandaroux
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Patent number: 10653716Abstract: An injectable monophase hydrogel is provided that is made of a reaction mixture of hyaluronic acids having different molecular weights.Type: GrantFiled: September 20, 2018Date of Patent: May 19, 2020Assignee: ALLERGAN INDUSTRIE, SASInventor: Pierre F. Lebreton
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Patent number: 10624988Abstract: Provided are injectable, hyaluronic acid-based hydrogel compositions including conjugated vitamins.Type: GrantFiled: January 30, 2017Date of Patent: April 21, 2020Assignee: Allergan Industrie, SASInventors: Futian Liu, Xiaojie Yu, Nicholas J. Manesis, Athene Wan Chie Chan
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Patent number: 10595977Abstract: Devices and methods for inserting an implant into skin or other tissue of a patient can include an insertion device that can enclose and support a hyaluronic thread as it is injected into a patient's skin or other tissue. The device can include a cover member, a non-tubular support member, and the thread. The cover member can have a proximal portion, a closed distal portion, and an inner cavity extending from the proximal portion toward the closed distal portion. The thread can be positioned along a longitudinal length of support member, between the support member and the cover member. The non-tubular support member can extend within the inner cavity of the cover member. The cover member can be moveable relative to the support member to expose the thread.Type: GrantFiled: January 24, 2017Date of Patent: March 24, 2020Assignee: Allergan Industrie, SASInventors: Antoine Duc, Bastien Mandaroux
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Patent number: 10485896Abstract: Disclosed herein are cohesive soft tissue fillers, for example, dermal and subdermal fillers, based on hyaluronic acids and pharmaceutically acceptable salts thereof. In one aspect, hyaluronic acid-based compositions described herein include a therapeutically effective amount of at least one anesthetic agent, for example, lidocaine. The present hyaluronic acid-based compositions including lidocaine have an enhanced stability and cohesivity, relative to conventional compositions including lidocaine, for example when subjected to sterilization techniques or when stored for long periods of time. Methods and processes of preparing such hyaluronic acid-based compositions are also provided.Type: GrantFiled: November 9, 2018Date of Patent: November 26, 2019Assignee: ALLERGAN INDUSTRIE SASInventor: Pierre F. Lebreton
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Patent number: 10391202Abstract: Disclosed herein are soft tissue fillers, for example, dermal and subdermal fillers, based on hyaluronic acids and pharmaceutically acceptable salts thereof. In one aspect, hyaluronic acid-based compositions described herein include a therapeutically effective amount of at least one anesthetic agent, for example, lidocaine. The present hyaluronic acid-based compositions including lidocaine have an enhanced stability, relative to conventional compositions including lidocaine, for example when subjected to sterilization techniques or when stored for long periods of time. Methods and processes of preparing such hyaluronic acid-based compositions are also provided.Type: GrantFiled: November 9, 2018Date of Patent: August 27, 2019Assignee: Allergan Industrie SASInventor: Pierre F. Lebreton
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Patent number: 10265151Abstract: Devices and methods for inserting an implant into skin or other tissue of a patient can include an insertion device having moveable portions that can retain, move, or otherwise control engagement and injection of a hyaluronic thread. The device can include a tubular member and a handle. The handle can include two or more components that each include apertures through which a needle can be placed. The handle can be manipulated to align or offset the apertures with respect to each other to modify a clearance through the apertures and selectively engage or disengage the needle or thread.Type: GrantFiled: January 24, 2017Date of Patent: April 23, 2019Assignee: ALLERGAN INDUSTRIE SASInventors: Antoine Duc, Bastien Mandaroux