Abstract: Separation and enrichment of isotopes are effected and rates and products of reactions are controlled by methods employing magnetic isotope effect. By virtue of the invention, when dibenzyl ketone was photolyzed to partial conversion in a dimensionally restricted environment (micelles in soap solution) .sup.13 C enrichment of over 100% was achieved. The .sup.13 C enrichment was found to occur specifically at the carbonyl carbon and to be magnetic field dependent.