Abstract: Disclosed herein are methods of detecting a target nucleic acid sequence, determining the localization of the target nucleic acid sequence, and/or quantifying the number of target nucleic acid sequences in a cell. This method may be used on small target nucleic acid sequences, and may be referred to as Nano-FISH.
Type:
Grant
Filed:
July 19, 2017
Date of Patent:
June 7, 2022
Assignee:
Altius Institute for Biomedical Sciences
Inventors:
John A. Stamatoyannopoulos, Shreeram Akilesh, Vivek Nandakumar