Patents Assigned to AMAZÔNIA FITOMEDICAMENTOS LTDA
  • Active fraction of a polar solvent extract from the latex of euphorbiaceae plants
    Patent number: 10143673
    Abstract: The present invention generally refers to an active fraction of an extract of the latex of plants from the family Euphorbiaceae in a polar solvent, as well as of one or more compounds contained therein, as well as the use of said fraction and/or said compounds, particularly in the treatment of cancer. The invention also refers to compositions comprising said active fraction and/or said compounds, as well as their use for the treatment of diseases concerning cell proliferation/angiogenesis, particularly cancer.
    Type: Grant
    Filed: May 19, 2015
    Date of Patent: December 4, 2018
    Assignee: AMAZONIA FITOMEDICAMENTOS LTDA.
    Inventors: Luiz F. Pianowski, Claudio P. Chaves, Joao B. Calixto
  • Ingenol derivatives in the reactivation of latent HIV
    Patent number: 10105339
    Abstract: The present invention broadly relates to the use of certain ingenol derivatives as HIV reactivators of latent HIV virus in viral reservoirs. In another aspect, the present invention relates to an association comprising such ingenol derivatives and antiretroviral agents substantially active against actively replicating virus.
    Type: Grant
    Filed: March 1, 2013
    Date of Patent: October 23, 2018
    Assignee: AMAZÔNIA FITOMEDICAMENTOS LTDA
    Inventors: Luiz Francisco Pianowski, Amilcar Tanuri
  • Ingenol derivative compounds and methods useful for inhibiting cancer cell viability and treating cancer
    Patent number: 9713601
    Abstract: The present invention relates to new ingenol derivative compounds for inhibiting cancer cell viability and treating cancer. In other aspects, the invention relates to a pharmaceutical composition, a medicament, methods for treating cancer, and a dosage form.
    Type: Grant
    Filed: April 8, 2016
    Date of Patent: July 25, 2017
    Assignee: AMAZÔNIA FITOMEDICAMENTOS LTDA
    Inventors: Luiz Francisco Pianowski, Everardo Ferreira Telles
  • Pharmaceutical uses of lanosta-8,24-dien-3-ols
    Patent number: 9238036
    Abstract: The invention generally refers to pharmaceutical uses of lanosta-8,24-dien-3-ols, a family of tetracyclic terpenols, as anti-inflammatory, anticancerigenous and analgesic agents via the inhibition of the disordered activation of serine-threonine protein kinases, particularly PKC.
    Type: Grant
    Filed: August 5, 2008
    Date of Patent: January 19, 2016
    Assignee: AMAZONIA FITOMEDICAMENTOS LTDA
    Inventors: Luiz Francisco Pianowski, Joao Batista Calixto, Paulo Cesar Leal, Claudio Paulino Chaves
  • ACTIVE FRACTION OF A POLAR SOLVENT EXTRACT FROM THE LATEX OF EUPHORBIACEAE PLANTS
    Publication number: 20150359774
    Abstract: The present invention generally refers to an active fraction of an extract of the latex of plants from the family Euphorbiaceae in a polar solvent, as well as of one or more compounds contained therein, as well as the use of said fraction and/or said compounds, particularly in the treatment of cancer. The invention also refers to compositions comprising said active fraction and/or said compounds, as well as their use for the treatment of diseases concerning cell proliferation/angiogenesis, particularly cancer.
    Type: Application
    Filed: May 19, 2015
    Publication date: December 17, 2015
    Applicant: AMAZONIA FITOMEDICAMENTOS LTDA.
    Inventors: Luiz F. PIANOWSKI, Claudio P. CHAVES, Joao B. CALIXTO
  • Ingenol Derivatives in the Reactivation of Latent HIV
    Publication number: 20150030638
    Abstract: The present invention broadly relates to the use of certain ingenol derivatives as HIV reactivators of latent HIV virus in viral reservoirs. In another aspect, the present invention relates to an association comprising such ingenol derivatives and antiretroviral agents substantially active against actively replicating virus.
    Type: Application
    Filed: March 1, 2013
    Publication date: January 29, 2015
    Applicant: AMAZÔNIA FITOMEDICAMENTOS LTDA.
    Inventors: Luiz Francisco Pianowski, Amilcar Tanuri
  • Pharmaceutical Use of Multicyclic Compounds as Anti-Aids Agents
    Publication number: 20120289487
    Abstract: This invention refers to pharmaceutical use of multicyclic compounds chosen from ingenols, lanosta-8,24-dien-3-ols and their mixtures, as anti-AIDS agents.
    Type: Application
    Filed: January 15, 2010
    Publication date: November 15, 2012
    Applicant: AMAZÔNIA FITOMEDICAMENTOS LTDA
    Inventors: Luiz Francisco Pianowski, Joao Batista Calixto, Claudio Paulino Chaves
  • Pharmaceutical Uses of Lanosta-8,24-dien-3-ols
    Publication number: 20110136773
    Abstract: The invention generally refers to pharmaceutical uses of lanosta-8,24-dien-3-ols, a family of tetracyclic terpenols, as anti-inflammatory, anticancerigenous and analgesic agents via the inhibition of the disordered activation of serine-threonine protein kinases, particularly PKC.
    Type: Application
    Filed: August 5, 2008
    Publication date: June 9, 2011
    Applicant: AMAZONIA FITOMEDICAMENTOS LTDA
    Inventors: Luiz Francisco Pianowski, Joao Batista Calixto, Paulo Cesar Leal, Claudio Paulino Chaves
  • ACTIVE FRACTION OF A POLAR SOLVENT EXTRACT FROM THE LATEX OF EUPHORBIACEAE PLANTS
    Publication number: 20090142421
    Abstract: The present invention generally refers to an active fraction of an extract of the latex of plants from the family Euphorbiaceae in a polar solvent, as well as of one or more compounds contained therein, as well as the use of said fraction and/or said compounds, particularly in the treatment of cancer. The invention also refers to compositions comprising said active fraction and/or said compounds, as well as their use for the treatment of diseases concerning cell proliferation/angiogenesis, particularly cancer.
    Type: Application
    Filed: June 28, 2005
    Publication date: June 4, 2009
    Applicant: AMAZONIA FITOMEDICAMENTOS LTDA.
    Inventors: Luiz F. Pianowski, Claudio P. Chaves, Joao B. Calixto