Abstract: Apparatus and methods are provided to concentrate energy delivery in non-superficial target tissue within a trigone region of a human bladder wall to modulate bladder function.

Abstract: Apparatus and methods are provided to concentrate energy delivery in non-superficial target tissue within a trigone region of a human bladder wall to modulate bladder function.

Abstract: Apparatus and methods are provided to concentrate energy delivery in non-superficial target tissue within a trigone region of a human bladder wall to modulate bladder function.

Abstract: A device and method that provides a minimally-invasive approach to performing treatments on soft tissue, such as that found in the bladder. The device is useful for manipulating tissue such that treatment tools can be inserted into the tissue at a controlled depth.

Abstract: A device and method that provides a minimally-invasive approach to performing treatments on soft tissue, such as that found in the bladder. The device is useful for manipulating tissue such that treatment tools can be inserted into the tissue at a controlled depth. In some implementations, the device and method described herein are suited to provide therapy to non-mucosal target tissue (or a target volume of tissue) to modulate bladder function. In an example, energy can be delivered to denervate selected portions of the bladder, such as afferent nerves.

Abstract: Apparatus and methods are provided to concentrate energy delivery in non-superficial target tissue within a trigone region of a human bladder wall to modulate bladder function.

Abstract: Devices and methods that provide minimally-invasive approaches to performing treatments on soft tissue, such as that found in the bladder using various natural access paths such as transvaginal and transurethral. Treatments include the application of energy to nerves found in, under and around the trigone region of the bladder.

Abstract: Apparatus and methods are provided to concentrate energy delivery in non-superficial target tissue within a trigone region of a human bladder wall to modulate bladder function.

Abstract: Apparatus and methods are provided to concentrate energy delivery in non-superficial target tissue within a trigone region of a human bladder wall to modulate bladder function.

Abstract: Apparatus and methods to modulate bladder function are provided. An energy delivery apparatus can include an elongated shaft, a distal region coupled to the elongated shaft, and an energy delivery element configured to deliver energy to non-superficial target tissue within a trigone region of a bladder wall of a human bladder to modulate bladder function.

Abstract: Apparatus and methods are provided to concentrate energy delivery in non-superficial target tissue within a trigone region of a human bladder wall to modulate bladder function.

Abstract: Quinoline- and isoquinoline-based compounds exhibiting ATP-utilizing enzyme inhibitory activity, methods of using compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions comprising compounds exhibiting ATP-utilizing enzyme inhibitory activity, are disclosed.

Abstract: A method of toroid writing and reading of information, consisting in that from toroid-like patterns made from a magnetic material the structures are organized, comprising information and reference patterns, having a closed magnetic flux of the appropriate twisting direction. When writing the alternative information, on changes the twisting direction of the closed magnetic flux in appropriate information patterns by exposing them to the coordinated in the time and magnitude action of mutually intersecting biasing and magnetic reversal alternating magnetic fields, and when reading the information, one acts on the information and the reference patterns by an alternative biasing magnetic field, afterwards detects the output signals and on the character of their responses determines the value of the information unit written into the information pattern.

Abstract: A lightweight, portable apparatus for carrying skis and ski poles having a relatively rigid body member formed of a lightweight, easily molded material having one end formed with generally C-shaped clips to receive and hold a pair of parallel ski poles. One end of an elongated elastic strap is mounted on the body member to encircle a pair of parallel skis. The opposite end of the strap has locking means which engage the body member to maintain the elastic strap in tension around the skis and hold them tightly and securely together.