Patents Assigned to Amulet Pharmaceuticals, Inc.
  • Patent number: 8894985
    Abstract: This invention relates to compositions comprising carbon-based diazeniumdiolates attached to hydrophobic polymers that releases nitric oxide (NO). The carbon-based diazeniumdiolated polymers release NO spontaneously under physiological conditions without subsequence nitrosamine formation. The present invention also relates to methods of preparing the carbon-based diazeniumdiolated polymers, compositions comprising such polymers, methods of using such compositions, and devices employing such polymer compositions.
    Type: Grant
    Filed: November 5, 2010
    Date of Patent: November 25, 2014
    Assignee: Amulet Pharmaceuticals, Inc.
    Inventors: Ernst V. Arnold, Blaine G. Doletski, Robert E. Raulli
  • Patent number: 7829553
    Abstract: This invention relates to compositions comprising carbon-based diazeniumdiolates attached to hydrophobic polymers that releases nitric oxide (NO). The carbon-based diazeniumdiolated polymers release NO spontaneously under physiological conditions without subsequent nitrosamine formation. The present invention also relates to methods of preparing the carbon-based diazeniumdiolated polymers, compositions comprising such polymers, methods of using such compositions, and devices employing such polymer compositions.
    Type: Grant
    Filed: January 6, 2005
    Date of Patent: November 9, 2010
    Assignee: Amulet Pharmaceuticals, Inc.
    Inventors: Ernst V. Arnold, Blaine G. Doletski, Robert E. Raulli