Patents Assigned to Andreas Hettich GmbH & Co. KG
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Publication number: 20150174539Abstract: The invention relates to an apparatus for the homogenization and separation of media (10), comprising a centrifuge (40, 70) having a centrifuge rotor (14, 44, 74) which can be rotated about a motor axis (A) of a centrifuge motor (12, 42, 72) and which includes a rotor body, connected to which is at least one rotation unit (16, 48, 80) in such a way that it is additionally adapted to be rotatable about an axis of rotation of a rotation unit, which axis is different from the motor axis (A), and that it can be driven via a rotation unit drive, with means being provided which can be used to set at least two different rotation speeds of the rotation unit (16, 48, 80), and furthermore the rotation unit (16, 48, 80) has toothing (8) on its periphery by which the rotation unit (16, 48, 80) can be driven. The invention is characterized in that the rotation unit drive comprises toothing which is associated with the centrifuge motor.Type: ApplicationFiled: July 2, 2013Publication date: June 25, 2015Applicants: KTB TUMORFORSCHUNGSGESELLSCHAFT MBH, ANDREAS HETTICH GMBH & CO. KGInventors: Klaus-Gunter Eberle, Anke Lenz, Ulrich Massing, Vittorio Ziroli
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Patent number: 9022775Abstract: The invention relates to a method and a device for producing a moulded body having microstructures from moulding material. The method for producing a moulded body having microstructures on a carrier out of moulding material is effected by inputting a moulding material into a container (10) comprising a mould cavity (14), wherein at least one micro-structured mould (12) is provided in the mould cavity. Furthermore, the centrifugation of a container (10) is carried out until the moulding material has completely entered into the structure of the mould (12). Thereafter, the curing of the moulding material is carried out to form a moulded body having microstructures, which is then removed from the mould (12) and the container (10).Type: GrantFiled: December 17, 2009Date of Patent: May 5, 2015Assignee: Andreas Hettich GmbH & Co. KGInventors: Thomas Hipp, Frank Gehring
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Patent number: 8997557Abstract: The invention relates to an apparatus (10) for carrying out measurements of a analyte fluid having a housing (12, 18), a measurement chamber (40) arranged in the housing (18), a resonator (16, 34) and conduits (42, 44) for inputting and outputting media for the measurements into/out of the measurement chamber (40), wherein the resonators (16, 34) delimit the measurement chamber (40) in areas. The invention distinguishes thereby that two resonators (16, 34) are provided which delimit the measurements chamber (40) each.Type: GrantFiled: June 19, 2009Date of Patent: April 7, 2015Assignee: Andreas Hettich GmbH & Co. KGInventor: Frank Gehring
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Patent number: 8992403Abstract: A cartridge (1) for accommodating blood bags (35) to be inserted into a centrifuge is used for the separation of blood components. Said cartridge (1) is provided with a partition wall (3) which separates a blood bag section (5) positioned radially inside from a product section (7) positioned radially outside, wherein a fixture (29) for a filter (31) is provided in the product section (7), a product transport path (36) which leads from the blood bag section (5) via the fixture (29) for the filter (31) to the product section (7). The product transport path (36) coming from the blood bag section (5) leads into the fixture (29) for the filter (31) radially from the outside and from below.Type: GrantFiled: June 4, 2008Date of Patent: March 31, 2015Assignees: Terumo BCT, Inc., Andreas Hettich GmbH & Co. KGInventors: Klaus-Günter Eberle, Roland Biset
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Patent number: 8951180Abstract: The invention refers to a centrifuge for separating whole blood into its blood components and a method for extracting a highly enriched thrombocyte concentrate out of whole blood. For this purpose, the centrifuge comprises a closed loop and/or open-loop control unit as well as a drive unit coupled to the closed loop and/or open-loop control unit, a rotor (12) having at least two container receptacles (14a, 14b; 16a, 16) for removably holding containers (18, 20, 22, 24) being in fluid communication with each other, at least one sensor arranged between the container receptacles (14a, 14b; 16a, 16b) and coupled with the closed loop and/or open-loop control unit for detecting a separation layer. Herein, a motor/gear unit (30a, 30b, 32a, 32b) coupled to the closed loop and/or open-loop control unit is associated with each of the container receptacles (14a, 14b; 16a, 16b).Type: GrantFiled: September 3, 2010Date of Patent: February 10, 2015Assignee: Andreas Hettich GmbH & Co. KGInventor: Klaus-Günter Eberle
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Patent number: 8920702Abstract: The invention relates to a method and a device for producing a molded body having microstructures from molding material. The method for producing a molded body having microstructures on a carrier out of molding material is effected by inputting a molding material into a container (10) comprising a mold cavity (14), wherein at least one micro-structured mold (12) is provided in the mold cavity. Furthermore, the centrifugation of a container (10) is carried out until the molding material has completely entered into the structure of the mold (12). Thereafter, the curing of the molding material is carried out to form a molded body having microstructures, which is then removed from the mold (12) and the container (10).Type: GrantFiled: June 19, 2012Date of Patent: December 30, 2014Assignee: Andreas Hettich GmbH & Co. KGInventors: Thomas Hipp, Frank K. Gehring
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Publication number: 20140348726Abstract: A centrifuge container comprising a centrifuge bucket, a locking lever and a lid is disclosed. The lid is adapted to be locked on the centrifuge bucket, and the locking lever is adapted to be pivoted from an open position to a closed position. The lid and centrifuge bucket can be made to engage each other via respective connection means by means of the locking lever such that the lid will be locked in place in the closed position of the lever and will be released in the open position of the lever. The locking lever is provided in the form of a carrying handle and that carrying handle is adapted to be pivotably mounted on one carrying handle mounting unit integrally formed on the centrifuge bucket, and that the carrying handle, in its closed position, allows the centrifuge container to be carried by means of the carrying handle.Type: ApplicationFiled: December 7, 2012Publication date: November 27, 2014Applicant: ANDREAS HETTICH GMBH & CO. KGInventor: Andreas Hölderle
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Patent number: 8883510Abstract: The invention relates to a method for determining haemostasis parameters by measuring vibration parameters of a resonator having a measuring surface which contacts a platelet containing sample fluid. The invention is characterized by the analysis of the characteristic of a vibration parameter over time, based on which the platelet function will then be assessed and a distinction will be made between the presence of an adhesion disorder or that of an aggregation disorder.Type: GrantFiled: September 9, 2010Date of Patent: November 11, 2014Assignee: Andreas Hettich GmbH & Co. KGInventors: Frank K. Gehring, Hans Wendel, Stefan Sinn, Lothar Mueller
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Patent number: 8870734Abstract: The invention relates to a cartridge (1) for accommodating blood bags (35), which is provided for the separation of blood components for the application in a centrifuge. The cartridge (1) has a partition wall (3) which separates a blood bag section (5) positioned radially inside from a product section (7) positioned radially outside, and a cover (9) disposed in a mounting position above the blood bag section (5). The cover (9) is connected to the partition wall (3) pivotally in a first point (11) and detachably in a second point (13), so that the blood bag section (5) is freely accessible by means of laterally pivoting the cover (9) out of the way. The cartridge is applicable in the rotor of a centrifuge.Type: GrantFiled: June 4, 2008Date of Patent: October 28, 2014Assignees: Terumo BCT, Inc., Andreas Hettich GmbH & Co. KGInventors: Klaus-Günter Eberle, Roland Biset
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Publication number: 20140315707Abstract: The invention relates to a method for automatically loading a swinging bucket centrifuge with sample containers, and, the swinging bucket centrifuge being adapted to accommodate a centrifuge carrier which has a plurality of receiving pockets positioned according to a predetermined receiving pocket pattern. The invention is characterized in that the centrifuge carrier is placed in a swinging bucket, with the positioning pattern for the sample containers being determined such that the center of gravity of the moved masses will be on the centrifuge axis during centrifugation when the centrifuge buckets have assumed their swung out positions.Type: ApplicationFiled: October 24, 2012Publication date: October 23, 2014Applicant: ANDREAS HETTICH GMBH & CO. KGInventor: Klaus-Guenter Eberle
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Patent number: 8756981Abstract: The invention relates to a measurement device with at least one resonator, comprising a measurement chamber with a fluidic input and a fluidic output wherein the measurement chamber is delimited, at its bottom surface, by a resonator, and wherein the resonator surface is configured to be electrically conducting, and the resonator surface forms the working electrode for an electrochemical measurement, and wherein electrodes are provided at the fluidic input and/or output at the transition to the measurement chamber. The invention is characterized in that the electrodes are exchangeable and allow the reception of a fluidic connection.Type: GrantFiled: March 21, 2011Date of Patent: June 24, 2014Assignee: Andreas Hettich GmbH & Co. KGInventor: Frank K. Gehring
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Publication number: 20140030802Abstract: The invention relates to an air-conditioning space (10) for storing samples in a time-controlled manner, comprising a device (22) for automatically feeding sample containers (18) into a climatically sealed space (12) having at least one wall (43), into which a sample container (18) can be inserted into the climatically sealed space (12) through an opening (40, 42), wherein the feed device (22) has at least one drive and control unit, and an incubator receptacle (30) for receiving the samples (18) is provided inside the climatically sealed space (12). The invention is distinguished by the fact that the feed device has an automatic feed arm (22, 24) which grips a sample container (18) from a receiving position outside the climatically sealed space (12) and deposits the sample container (18) there in a clear deposit position in an incubator receptacle (30).Type: ApplicationFiled: November 17, 2011Publication date: January 30, 2014Applicant: ANDREAS HETTICH GMBH & CO. KGInventors: Klaus-Guenter Eberle, Gavin Clarke
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Publication number: 20130239527Abstract: The invention relates to a method for automatically handling a sample container (100), wherein at least one sample container (100) is taken up in a container carrier (30) in a handling device (95) and a lid (101) is gripped by a gripper head (50) with a predetermined gripping force and the lid (101) is removed by a combined movement out of a translational and rotational movement from the sample container (100), characterized in that, by means of an optical capturing, the lid (101) as well as the sample con- tainer (100) are analyzed and are assigned to a lid and sample container type, and that, furthermore, a required torque is assigned to each lid and/or sample container type as required for removing the lid (101), and that, starting from this torque, the gripping force of the gripper head (50) is adjusted.Type: ApplicationFiled: November 27, 2012Publication date: September 19, 2013Applicant: ANDREAS HETTICH GMBH & CO. KGInventors: Gavin CLARKE, Klaus-Guenter EBERLE
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Publication number: 20130206268Abstract: The invention relates to a connecting device for the fluidic contacting of a microfluidic chip (12), wherein openings are introduced in the surface of the microfluidic chip (12) and the connecting device comprises a carrier plate (14) and at least one connector (16). The invention is characterized in that the connector (16) comprises a sleeve 22 and a flange (26) arranged coaxially with respect to the sleeve 22 and the inside diameter of the sleeve 22 is dimensioned such that it receives a microfluidic hose (30) and the outside diameter is dimensioned such that the sleeve 22 can be received in a cut-out introduced in the carrier plate (14).Type: ApplicationFiled: September 14, 2011Publication date: August 15, 2013Applicant: ANDREAS HETTICH GMBH & CO. KGInventor: Frank K Gehring
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Publication number: 20130125629Abstract: The invention relates to a measuring device (10, 50) comprising a resonator (20, 52) having a sensitive region and a base support unit (26, 30) for measuring properties of a fluid, the resonator (20, 52) being inserted in the base support unit (26, 30) and contacted therein, the sensitive region remaining accessible to the fluid, and the resonator (20, 52) being activatable via connection points (24, 40) on the base support unit (26, 30). The invention is characterized in that the base support unit (26, 30) is formed solely by a film arrangement.Type: ApplicationFiled: March 23, 2011Publication date: May 23, 2013Applicant: ANDREAS HETTICH GMBH & CO. KGInventor: Frank K. Gehring
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Publication number: 20130130883Abstract: The invention pertains to a cassette (2) comprising a product conveying path (1, 1a, 1b) and a positioning means (3a, 3b) engageable with a counter-piece on a centrifuge having a rotor for separating blood components or on a system component (4) arranged in a centrifuge. The positioning is effected such that a section of the product conveying path (1, 1a, 1b) is aligned with a section of the centrifuge or the system component arranged in the centrifuge. Furthermore, a tube connected with bags is accommodated in the product conveying path (1, 1a, 1b).Type: ApplicationFiled: January 5, 2011Publication date: May 23, 2013Applicants: TERUMO EUROPE N.V., ANDREAS HETTICH GMBH & CO. KGInventors: Klaus-Günter Eberle, Roland Biset, Wilfried Mertens
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Publication number: 20130072368Abstract: The invention pertains to a cassette (2) comprising a product conveying path (1, 1a, 1b) and a shut-off device (19a, 19b) integrated into the cassette for interrupting a product flow. The shut-off device is arranged at a rim of the cassette such that the shut-off device (19a, 19b) can be directly operated manually and/or mechanically. The product-conveying path (1, 1a, 1b) leads through the shut-off device (19a, 19b). The cassette consists of a lower part (5) and an upper part (7) which are connectable to each other by connecting means (9, 11, 13, 15).Type: ApplicationFiled: January 5, 2011Publication date: March 21, 2013Applicants: TERUMO EUROPE NV, ANDREAS HETTICH GMBH & CO. KGInventors: Klaus-Günter Eberle, Roland Biset, Wilfried Mertens
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Publication number: 20120286454Abstract: The invention relates to a method and a device for producing a moulded body having microstructures from moulding material. The method for producing a moulded body having microstructures on a carrier out of moulding material is effected by inputting a moulding material into a container (10) comprising a mould cavity (14), wherein at least one micro-structured mould (12) is provided in the mould cavity. Furthermore, the centrifugation of a container (10) is carried out until the moulding material has completely entered into the structure of the mould (12). Thereafter, the curing of the moulding material is carried out to form a moulded body having microstructures, which is then removed from the mould (12) and the container (10).Type: ApplicationFiled: June 19, 2012Publication date: November 15, 2012Applicant: ANDREAS HETTICH GMBH & CO. KGInventors: THOMAS HIPP, FRANK K. GEHRING
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Publication number: 20120275959Abstract: The invention relates to a device for measuring coagulation parameters in a sample fluid, comprising an interface sensor with a sensor surface that faces the sample fluid. The invention is characterized in that said sensor surface includes adhesive areas and non-adhesive areas with respect to blood components.Type: ApplicationFiled: September 9, 2009Publication date: November 1, 2012Applicant: ANDREAS HETTICH GMBH & CO. KGInventors: Frank Gehring, Lothar Mueller
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Publication number: 20120270326Abstract: The invention relates to a method for determining haemostasis parameters by measuring vibration parameters of a resonator having a measuring surface which contacts a platelet containing sample fluid. The invention is characterized by the analysis of the characteristic of a vibration parameter over time, based on which the platelet function will then be assessed and a distinction will be made between the presence of an adhesion disorder or that of an aggregation disorder.Type: ApplicationFiled: September 9, 2010Publication date: October 25, 2012Applicant: ANDREAS HETTICH GMBH & CO. KGInventors: Frank K. Gehring, Hans Wendel, Stefan Sinn, Lothar Mueller