Patents Assigned to Andreas Hettich GmbH & Co. KG
  • Publication number: 20150174539
    Abstract: The invention relates to an apparatus for the homogenization and separation of media (10), comprising a centrifuge (40, 70) having a centrifuge rotor (14, 44, 74) which can be rotated about a motor axis (A) of a centrifuge motor (12, 42, 72) and which includes a rotor body, connected to which is at least one rotation unit (16, 48, 80) in such a way that it is additionally adapted to be rotatable about an axis of rotation of a rotation unit, which axis is different from the motor axis (A), and that it can be driven via a rotation unit drive, with means being provided which can be used to set at least two different rotation speeds of the rotation unit (16, 48, 80), and furthermore the rotation unit (16, 48, 80) has toothing (8) on its periphery by which the rotation unit (16, 48, 80) can be driven. The invention is characterized in that the rotation unit drive comprises toothing which is associated with the centrifuge motor.
    Type: Application
    Filed: July 2, 2013
    Publication date: June 25, 2015
    Applicants: KTB TUMORFORSCHUNGSGESELLSCHAFT MBH, ANDREAS HETTICH GMBH & CO. KG
    Inventors: Klaus-Gunter Eberle, Anke Lenz, Ulrich Massing, Vittorio Ziroli
  • Patent number: 9022775
    Abstract: The invention relates to a method and a device for producing a moulded body having microstructures from moulding material. The method for producing a moulded body having microstructures on a carrier out of moulding material is effected by inputting a moulding material into a container (10) comprising a mould cavity (14), wherein at least one micro-structured mould (12) is provided in the mould cavity. Furthermore, the centrifugation of a container (10) is carried out until the moulding material has completely entered into the structure of the mould (12). Thereafter, the curing of the moulding material is carried out to form a moulded body having microstructures, which is then removed from the mould (12) and the container (10).
    Type: Grant
    Filed: December 17, 2009
    Date of Patent: May 5, 2015
    Assignee: Andreas Hettich GmbH & Co. KG
    Inventors: Thomas Hipp, Frank Gehring
  • Patent number: 8997557
    Abstract: The invention relates to an apparatus (10) for carrying out measurements of a analyte fluid having a housing (12, 18), a measurement chamber (40) arranged in the housing (18), a resonator (16, 34) and conduits (42, 44) for inputting and outputting media for the measurements into/out of the measurement chamber (40), wherein the resonators (16, 34) delimit the measurement chamber (40) in areas. The invention distinguishes thereby that two resonators (16, 34) are provided which delimit the measurements chamber (40) each.
    Type: Grant
    Filed: June 19, 2009
    Date of Patent: April 7, 2015
    Assignee: Andreas Hettich GmbH & Co. KG
    Inventor: Frank Gehring
  • Patent number: 8992403
    Abstract: A cartridge (1) for accommodating blood bags (35) to be inserted into a centrifuge is used for the separation of blood components. Said cartridge (1) is provided with a partition wall (3) which separates a blood bag section (5) positioned radially inside from a product section (7) positioned radially outside, wherein a fixture (29) for a filter (31) is provided in the product section (7), a product transport path (36) which leads from the blood bag section (5) via the fixture (29) for the filter (31) to the product section (7). The product transport path (36) coming from the blood bag section (5) leads into the fixture (29) for the filter (31) radially from the outside and from below.
    Type: Grant
    Filed: June 4, 2008
    Date of Patent: March 31, 2015
    Assignees: Terumo BCT, Inc., Andreas Hettich GmbH & Co. KG
    Inventors: Klaus-Günter Eberle, Roland Biset
  • Patent number: 8951180
    Abstract: The invention refers to a centrifuge for separating whole blood into its blood components and a method for extracting a highly enriched thrombocyte concentrate out of whole blood. For this purpose, the centrifuge comprises a closed loop and/or open-loop control unit as well as a drive unit coupled to the closed loop and/or open-loop control unit, a rotor (12) having at least two container receptacles (14a, 14b; 16a, 16) for removably holding containers (18, 20, 22, 24) being in fluid communication with each other, at least one sensor arranged between the container receptacles (14a, 14b; 16a, 16b) and coupled with the closed loop and/or open-loop control unit for detecting a separation layer. Herein, a motor/gear unit (30a, 30b, 32a, 32b) coupled to the closed loop and/or open-loop control unit is associated with each of the container receptacles (14a, 14b; 16a, 16b).
    Type: Grant
    Filed: September 3, 2010
    Date of Patent: February 10, 2015
    Assignee: Andreas Hettich GmbH & Co. KG
    Inventor: Klaus-Günter Eberle
  • Patent number: 8920702
    Abstract: The invention relates to a method and a device for producing a molded body having microstructures from molding material. The method for producing a molded body having microstructures on a carrier out of molding material is effected by inputting a molding material into a container (10) comprising a mold cavity (14), wherein at least one micro-structured mold (12) is provided in the mold cavity. Furthermore, the centrifugation of a container (10) is carried out until the molding material has completely entered into the structure of the mold (12). Thereafter, the curing of the molding material is carried out to form a molded body having microstructures, which is then removed from the mold (12) and the container (10).
    Type: Grant
    Filed: June 19, 2012
    Date of Patent: December 30, 2014
    Assignee: Andreas Hettich GmbH & Co. KG
    Inventors: Thomas Hipp, Frank K. Gehring
  • Publication number: 20140348726
    Abstract: A centrifuge container comprising a centrifuge bucket, a locking lever and a lid is disclosed. The lid is adapted to be locked on the centrifuge bucket, and the locking lever is adapted to be pivoted from an open position to a closed position. The lid and centrifuge bucket can be made to engage each other via respective connection means by means of the locking lever such that the lid will be locked in place in the closed position of the lever and will be released in the open position of the lever. The locking lever is provided in the form of a carrying handle and that carrying handle is adapted to be pivotably mounted on one carrying handle mounting unit integrally formed on the centrifuge bucket, and that the carrying handle, in its closed position, allows the centrifuge container to be carried by means of the carrying handle.
    Type: Application
    Filed: December 7, 2012
    Publication date: November 27, 2014
    Applicant: ANDREAS HETTICH GMBH & CO. KG
    Inventor: Andreas Hölderle
  • Patent number: 8883510
    Abstract: The invention relates to a method for determining haemostasis parameters by measuring vibration parameters of a resonator having a measuring surface which contacts a platelet containing sample fluid. The invention is characterized by the analysis of the characteristic of a vibration parameter over time, based on which the platelet function will then be assessed and a distinction will be made between the presence of an adhesion disorder or that of an aggregation disorder.
    Type: Grant
    Filed: September 9, 2010
    Date of Patent: November 11, 2014
    Assignee: Andreas Hettich GmbH & Co. KG
    Inventors: Frank K. Gehring, Hans Wendel, Stefan Sinn, Lothar Mueller
  • Patent number: 8870734
    Abstract: The invention relates to a cartridge (1) for accommodating blood bags (35), which is provided for the separation of blood components for the application in a centrifuge. The cartridge (1) has a partition wall (3) which separates a blood bag section (5) positioned radially inside from a product section (7) positioned radially outside, and a cover (9) disposed in a mounting position above the blood bag section (5). The cover (9) is connected to the partition wall (3) pivotally in a first point (11) and detachably in a second point (13), so that the blood bag section (5) is freely accessible by means of laterally pivoting the cover (9) out of the way. The cartridge is applicable in the rotor of a centrifuge.
    Type: Grant
    Filed: June 4, 2008
    Date of Patent: October 28, 2014
    Assignees: Terumo BCT, Inc., Andreas Hettich GmbH & Co. KG
    Inventors: Klaus-Günter Eberle, Roland Biset
  • Publication number: 20140315707
    Abstract: The invention relates to a method for automatically loading a swinging bucket centrifuge with sample containers, and, the swinging bucket centrifuge being adapted to accommodate a centrifuge carrier which has a plurality of receiving pockets positioned according to a predetermined receiving pocket pattern. The invention is characterized in that the centrifuge carrier is placed in a swinging bucket, with the positioning pattern for the sample containers being determined such that the center of gravity of the moved masses will be on the centrifuge axis during centrifugation when the centrifuge buckets have assumed their swung out positions.
    Type: Application
    Filed: October 24, 2012
    Publication date: October 23, 2014
    Applicant: ANDREAS HETTICH GMBH & CO. KG
    Inventor: Klaus-Guenter Eberle
  • Patent number: 8756981
    Abstract: The invention relates to a measurement device with at least one resonator, comprising a measurement chamber with a fluidic input and a fluidic output wherein the measurement chamber is delimited, at its bottom surface, by a resonator, and wherein the resonator surface is configured to be electrically conducting, and the resonator surface forms the working electrode for an electrochemical measurement, and wherein electrodes are provided at the fluidic input and/or output at the transition to the measurement chamber. The invention is characterized in that the electrodes are exchangeable and allow the reception of a fluidic connection.
    Type: Grant
    Filed: March 21, 2011
    Date of Patent: June 24, 2014
    Assignee: Andreas Hettich GmbH & Co. KG
    Inventor: Frank K. Gehring
  • Publication number: 20140030802
    Abstract: The invention relates to an air-conditioning space (10) for storing samples in a time-controlled manner, comprising a device (22) for automatically feeding sample containers (18) into a climatically sealed space (12) having at least one wall (43), into which a sample container (18) can be inserted into the climatically sealed space (12) through an opening (40, 42), wherein the feed device (22) has at least one drive and control unit, and an incubator receptacle (30) for receiving the samples (18) is provided inside the climatically sealed space (12). The invention is distinguished by the fact that the feed device has an automatic feed arm (22, 24) which grips a sample container (18) from a receiving position outside the climatically sealed space (12) and deposits the sample container (18) there in a clear deposit position in an incubator receptacle (30).
    Type: Application
    Filed: November 17, 2011
    Publication date: January 30, 2014
    Applicant: ANDREAS HETTICH GMBH & CO. KG
    Inventors: Klaus-Guenter Eberle, Gavin Clarke
  • Publication number: 20130239527
    Abstract: The invention relates to a method for automatically handling a sample container (100), wherein at least one sample container (100) is taken up in a container carrier (30) in a handling device (95) and a lid (101) is gripped by a gripper head (50) with a predetermined gripping force and the lid (101) is removed by a combined movement out of a translational and rotational movement from the sample container (100), characterized in that, by means of an optical capturing, the lid (101) as well as the sample con- tainer (100) are analyzed and are assigned to a lid and sample container type, and that, furthermore, a required torque is assigned to each lid and/or sample container type as required for removing the lid (101), and that, starting from this torque, the gripping force of the gripper head (50) is adjusted.
    Type: Application
    Filed: November 27, 2012
    Publication date: September 19, 2013
    Applicant: ANDREAS HETTICH GMBH & CO. KG
    Inventors: Gavin CLARKE, Klaus-Guenter EBERLE
  • Publication number: 20130206268
    Abstract: The invention relates to a connecting device for the fluidic contacting of a microfluidic chip (12), wherein openings are introduced in the surface of the microfluidic chip (12) and the connecting device comprises a carrier plate (14) and at least one connector (16). The invention is characterized in that the connector (16) comprises a sleeve 22 and a flange (26) arranged coaxially with respect to the sleeve 22 and the inside diameter of the sleeve 22 is dimensioned such that it receives a microfluidic hose (30) and the outside diameter is dimensioned such that the sleeve 22 can be received in a cut-out introduced in the carrier plate (14).
    Type: Application
    Filed: September 14, 2011
    Publication date: August 15, 2013
    Applicant: ANDREAS HETTICH GMBH & CO. KG
    Inventor: Frank K Gehring
  • Publication number: 20130125629
    Abstract: The invention relates to a measuring device (10, 50) comprising a resonator (20, 52) having a sensitive region and a base support unit (26, 30) for measuring properties of a fluid, the resonator (20, 52) being inserted in the base support unit (26, 30) and contacted therein, the sensitive region remaining accessible to the fluid, and the resonator (20, 52) being activatable via connection points (24, 40) on the base support unit (26, 30). The invention is characterized in that the base support unit (26, 30) is formed solely by a film arrangement.
    Type: Application
    Filed: March 23, 2011
    Publication date: May 23, 2013
    Applicant: ANDREAS HETTICH GMBH & CO. KG
    Inventor: Frank K. Gehring
  • Publication number: 20130130883
    Abstract: The invention pertains to a cassette (2) comprising a product conveying path (1, 1a, 1b) and a positioning means (3a, 3b) engageable with a counter-piece on a centrifuge having a rotor for separating blood components or on a system component (4) arranged in a centrifuge. The positioning is effected such that a section of the product conveying path (1, 1a, 1b) is aligned with a section of the centrifuge or the system component arranged in the centrifuge. Furthermore, a tube connected with bags is accommodated in the product conveying path (1, 1a, 1b).
    Type: Application
    Filed: January 5, 2011
    Publication date: May 23, 2013
    Applicants: TERUMO EUROPE N.V., ANDREAS HETTICH GMBH & CO. KG
    Inventors: Klaus-Günter Eberle, Roland Biset, Wilfried Mertens
  • Publication number: 20130072368
    Abstract: The invention pertains to a cassette (2) comprising a product conveying path (1, 1a, 1b) and a shut-off device (19a, 19b) integrated into the cassette for interrupting a product flow. The shut-off device is arranged at a rim of the cassette such that the shut-off device (19a, 19b) can be directly operated manually and/or mechanically. The product-conveying path (1, 1a, 1b) leads through the shut-off device (19a, 19b). The cassette consists of a lower part (5) and an upper part (7) which are connectable to each other by connecting means (9, 11, 13, 15).
    Type: Application
    Filed: January 5, 2011
    Publication date: March 21, 2013
    Applicants: TERUMO EUROPE NV, ANDREAS HETTICH GMBH & CO. KG
    Inventors: Klaus-Günter Eberle, Roland Biset, Wilfried Mertens
  • Publication number: 20120286454
    Abstract: The invention relates to a method and a device for producing a moulded body having microstructures from moulding material. The method for producing a moulded body having microstructures on a carrier out of moulding material is effected by inputting a moulding material into a container (10) comprising a mould cavity (14), wherein at least one micro-structured mould (12) is provided in the mould cavity. Furthermore, the centrifugation of a container (10) is carried out until the moulding material has completely entered into the structure of the mould (12). Thereafter, the curing of the moulding material is carried out to form a moulded body having microstructures, which is then removed from the mould (12) and the container (10).
    Type: Application
    Filed: June 19, 2012
    Publication date: November 15, 2012
    Applicant: ANDREAS HETTICH GMBH & CO. KG
    Inventors: THOMAS HIPP, FRANK K. GEHRING
  • Publication number: 20120275959
    Abstract: The invention relates to a device for measuring coagulation parameters in a sample fluid, comprising an interface sensor with a sensor surface that faces the sample fluid. The invention is characterized in that said sensor surface includes adhesive areas and non-adhesive areas with respect to blood components.
    Type: Application
    Filed: September 9, 2009
    Publication date: November 1, 2012
    Applicant: ANDREAS HETTICH GMBH & CO. KG
    Inventors: Frank Gehring, Lothar Mueller
  • Publication number: 20120270326
    Abstract: The invention relates to a method for determining haemostasis parameters by measuring vibration parameters of a resonator having a measuring surface which contacts a platelet containing sample fluid. The invention is characterized by the analysis of the characteristic of a vibration parameter over time, based on which the platelet function will then be assessed and a distinction will be made between the presence of an adhesion disorder or that of an aggregation disorder.
    Type: Application
    Filed: September 9, 2010
    Publication date: October 25, 2012
    Applicant: ANDREAS HETTICH GMBH & CO. KG
    Inventors: Frank K. Gehring, Hans Wendel, Stefan Sinn, Lothar Mueller