Abstract: A diagnostic device provides the flow of a desired reaction mixture under the force of gravity through a channel. The flow of the reaction mixture gains necessary energy to bring about a physical or a chemical reaction of the reaction mixture. A viewing chamber at the end of the channel retains results of the reaction. The device allows a timed reaction to take place without application of external forces such as vibration, rocking, optical activation, heat or pulsing. Alternative chambers at an entry end of the channel are used to introduce a secondary reaction mixture or reagents. A vent to the channel provides an indication of volume of the reactants and can also function as a viewing area. Channel configurations include various paths of flow and various inner wall geometries.

Abstract: Method of making and using products for analysis of specific ligands in solution. More specifically, a method of analyzing a sample for a ligand by incubating the sample with a ligand selective binder and with a predetermined amount of ligand, the binder and/or the predetermined amount of ligand being borne by particles of predetermined size, filtering the solution and analyzing the particles which pass through the filter and/or those particles that do not pass through the filter.