Patents Assigned to ANTAGONISTS OF TRPV1 RECEPTOR
  • ANTAGONISTS OF TRPV1 RECEPTOR
    Publication number: 20140121168
    Abstract: TRPV1 antagonists and associated methods are provided. A TRPV1 channel antagonist can have the structure: Formula (I) wherein R1 can be —CH3, —(CH2)X(CH)YCH3 where x+y=1-20, an aromatic, a (CH2)n aromatic where n can be less than or equal to 6, a lipid, or a linker, and wherein R2 can be either Formula (II) or Formula (III) Additionally, R3 can be —O—R4 or —NH—R4 and R4 can be —H, —CH3, an ester, a cyclic ester, or an amide.
    Type: Application
    Filed: April 26, 2012
    Publication date: May 1, 2014
    Applicant: ANTAGONISTS OF TRPV1 RECEPTOR
    Inventors: Eric Schmidt, Alan R. Light, Baldomero M. Olivera, Christopher A. Reilly, Zhejian Lin, Gisela P. Concepcion