Patents Assigned to Aphton Corp.
  • System for method for the modification and purification of proteins
    Patent number: 6359114
    Abstract: A system is described for conjugating, isolating, and purifying proteins. The system contains an ultrafiltration apparatus which is connected with a reaction vessel reservoir.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: March 19, 2002
    Assignee: Aphton Corp.
    Inventors: Stephen Grimes, Stephen L. Karr, Jr.
  • Immunogens against gonadotropin releasing hormone
    Patent number: 6132720
    Abstract: Immunogenic compositions capable of generating an immune response in mammals against GnRH are disclosed. The immunogenic compositions are effective in methods of treating gonadotropin and gonadal steroid hormone dependent diseases and immunological contraception of mammals.
    Type: Grant
    Filed: November 17, 1997
    Date of Patent: October 17, 2000
    Assignee: Aphton Corp.
    Inventors: Stephen Grimes, Robert Scibienski
  • Immunogens against gonadotropin releasing hormone
    Patent number: 5688506
    Abstract: Immunogenic compositions capable of generating an immune response in mammals against GnRH are disclosed. The immunogenic compositions are effective in methods of treating gonadotropin and gonadal steroid hormone dependent diseases and immunological contraception of mammals.
    Type: Grant
    Filed: January 27, 1994
    Date of Patent: November 18, 1997
    Assignee: Aphton Corp.
    Inventors: Stephen Grimes, Robert Scibienski
  • Immunogenic compositions against human gastrin 17
    Patent number: 5468494
    Abstract: An improved immunogenic composition against human gastrin 17 comprising the peptide pGlu-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Ser-Ser-Pro-Pro-Pro-Pro-Cys (SEQ ID NO.: 1) coupled to an immunogenic carrier and pharmaceutical compositions containing the same.
    Type: Grant
    Filed: November 12, 1993
    Date of Patent: November 21, 1995
    Assignee: Aphton Corp.
    Inventors: Philip C. Gevas, Stephen Grimes, Stephen L. Karr, Dov Michaeli, Robert Scibienski