Patents Assigned to Apoteksvarucentralen Vitrum AB
  • Composition for enhancing the administration of pharmacologically active agents
    Patent number: 4168308
    Abstract: According to the invention, the parenteral administration of water-insoluble pharmacologically active agents is enhanced wherein the agents are administered in the lipoid phase of a carrier emulsion comprising a microemulsion of a finely dispersed lipoid in an aqueous phase. The lipoid preferably has a mean particle size below 1 micron. This makes it possible to administer water-insoluble agents in high concentrations, and thus a lower dose, whereby a rapid onset of the pharmacological effect is accompanied by a markedly reduced incidence of injury to body tissues.
    Type: Grant
    Filed: November 23, 1977
    Date of Patent: September 18, 1979
    Assignee: Apoteksvarucentralen Vitrum AB
    Inventors: Karl A. J. Wretlind, Stellan Ljungberg, Ivan Hakansson, Bengt M. Ajaxon
  • Method of enhancing the administration of pharmalogically active agents
    Patent number: 4073943
    Abstract: According to the method of the invention, the parenteral administration of water-insoluble pharmacologically active agents is enhanced wherein the agents are administered in the lipoid phase of a carrier emulsion comprising a microemulsion of a finely dispersed lipoid in an aqueous phase. The lipoid preferably has a mean particle size below 1 micron. This makes it possible to administer water-insoluble agents in high concentrations, and thus a lower dose, whereby a rapid onset of the pharmacological effect is accompanied by a markedly reduced incidence of injury to body tissues.
    Type: Grant
    Filed: March 12, 1976
    Date of Patent: February 14, 1978
    Assignee: Apoteksvarucentralen Vitrum AB
    Inventors: Karl A. J. Wretlind, Stellan Ljungberg, Ivan Hakansson, Bengt M. Ajaxon