Abstract: The present invention relates generally to single nucleotide polymorphisms (SNP) associated with increased resistance of a rainbow trout (Oncorhynchus mykiss) to infectious pancreatic necrosis (IPN). In particular, the present invention provides methods for predicting increased resistance of a rainbow trout to infectious pancreatic necrosis (IPN) and methods for selecting a rainbow trout having increased resistant to infectious pancreatic necrosis. The present invention further provides rainbow trout, rainbow trout cells and populations thereof carrying at least one allele conferring IPN resistance (“IPN resistance allele”) in their genome as well as nucleic acid molecules comprising nucleotide sequences associated with the SNPs of the present invention.
Type:
Grant
Filed:
November 18, 2015
Date of Patent:
January 30, 2024
Assignee:
Aqua Gen AS
Inventors:
Nina Santi, Thomas Moen, Jørgen Ødegård
Abstract: The present invention relates to a method of predicting resistance to a viral infection in a subject, the method comprising determining in the subject the variant present at one or more amino acid position in a cadherin protein, and/or the alleles present at one or more DNA polymorphism in the gene for cadherin, and predicting whether or not the subject is resistant to viral infection based on the determination of the variant and/or the alleles.
Type:
Grant
Filed:
January 8, 2015
Date of Patent:
March 3, 2020
Assignee:
Aqua Gen AS
Inventors:
Thomas Moen, Jacob Seilo Torgersen, Nina K. Santi
Abstract: The present invention relates generally to single nucleotide polymorphisms (SNP) associated with increased resistance of a rainbow trout (Oncorhynchus mykiss)to infectious pancreatic necrosis (IPN). In particular, the present invention provides methods for predicting increased resistance of a rainbow trout to infectious pancreatic necrosis (IPN)and methods for selecting a rainbow trout having increased resistant to infectious pancreatic necrosis. The present invention further provides rainbow trout, rainbow trout cells and populations thereof carrying at least one allele conferring IPN resistance (“IPN resistance allele”) in their gen ome as well as nucleic acid molecules comprising nucleotide sequences associated with the SNPs of the present invention.
Type:
Application
Filed:
November 18, 2015
Publication date:
August 8, 2019
Applicant:
Aqua Gen AS
Inventors:
Nina Santi, Thomas Moen, Jørgen Ødegård
Abstract: The Invention relates to a method of predicting resistance to infectious pancreatic necrosis in salmon, the method comprising determining the alleles present at a DNA polymorphism in the salmon and predicting whether or not the salmon is resistant to infectious pancreatic necrosis based on the determination of the alleles. The invention also relates to a method of selecting a salmon for use as broodstock, wherein the salmon is selected based on the prediction by the first method that the salmon will have resistance to infectious pancreatic necrosis.