Abstract: Calcareous materials which are very purified residues of corallinaceae particulary Lithothamnium corallioides have unusual therapeutic properties including treatment of conditions created by failure of immune regulation, for example rheumatoid or osteo arthritis, osteoporosis and other conditions involving pH control. A method for purification is provided. Also provided are compositions of the residues together with fatty acids, glycerides, polyglycols and emulsifiers. Particularly advantageous are compositions of the residues and medium chain triglycerides.