Patents Assigned to Arteriocyte Medical Systems, Inc.
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Patent number: 11292014Abstract: Centrifuge counterbalances having an adjustable center of gravity are provided. Aspects of the centrifuge counterbalances include an elongated body having a distal end and a proximal end, a weight configured to be reversibly immobilized at a position along the longitudinal axis of the elongated body and a base configured to operably couple the centrifuge counterbalance to a centrifuge. Also provided are methods for balancing a centrifuge rotor when separating components of a liquid sample by centrifugation as well as systems suitable for practicing the subject methods.Type: GrantFiled: April 5, 2016Date of Patent: April 5, 2022Assignee: Arteriocyte Medical Systems, Inc.Inventors: Kenneth Welborn, Rodney Sparks
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Patent number: 11278884Abstract: Multi-component separation devices configured to separate components of a liquid sample by centrifugation are provided. Aspects of the separation devices include a container having a distal end and a proximal end and a buoy configured to be displaced along a longitudinal axis within the container where the buoy includes one or more sealed chambers. Also provided are methods of using the subject devices to separate components of a multi-component liquid sample such as whole blood, bone marrow aspirate or stromal vascular fraction as well as systems suitable for practicing the subject methods.Type: GrantFiled: October 27, 2015Date of Patent: March 22, 2022Assignee: Arteriocyte Medical Systems, Inc.Inventors: Rodney Sparks, John Raymond Chapman
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Patent number: 9096839Abstract: The present invention provides biological compositions and methods for making the same.Type: GrantFiled: April 26, 2007Date of Patent: August 4, 2015Assignee: Arteriocyte Medical Systems, Inc.Inventors: Tessy Kanayinkal, Laura A. Yonce, Debra Mullins-Hirte, Trevor C. Huang, Rohit Cariappa, Kenneth E. Merte, James R. Keogh, Kevin D. McIntosh, Brian J. Steffens, Asha S. Nayak, Erick L. Johnson
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Patent number: 8088099Abstract: Dispensing assemblies, methods, and kits of parts for dispensing two separate fluids to an treatment site, including entraining non-atomized flow of a first fluid in an atomized flow of a second fluid, delivering a first fluid upstream from a second fluid, delivering a first fluid and a second fluid with re-shapeable malleable tubes, delivering first and second fluids with releasable connectors maintained by a handle assembly, and kits of parts with angularly offset pockets.Type: GrantFiled: November 23, 2009Date of Patent: January 3, 2012Assignee: Arteriocyte Medical Systems, Inc.Inventors: Kevin D. McIntosh, Victor D. Dolecek
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Patent number: 7934603Abstract: The delivery system of the present invention is comprised of at least two chambers which store, individually, an activated blood component and an inactivated blood component. The first chamber comprises an activating agent and a filter which may be one in the same thus allowing the formed clot to be triturated thereby isolating the thrombin from the clot. The second chamber stores the inactivated blood component that when mixed with thrombin will produce a gel. The first or second chamber may further contain agents which are desired to be delivered to a specific site. The unique design of the delivery system allows for ease in operation of combining two agents at a specific time and place.Type: GrantFiled: May 2, 2005Date of Patent: May 3, 2011Assignee: Arteriocyte Medical Systems, Inc.Inventors: Julie S. Eaton, Robert F. Baugh, Lisa M. Lim, John G. Rivera, Victor D. Dolecek
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Patent number: 7897054Abstract: A flexible, disposable centrifuge bag for receiving and holding a fluid sample, comprising one or more tubes and upper and lower flexible sheets having doughnut shaped configurations. The upper and lower sheets are superimposed and completely sealed together at their outer perimeters to define an outer perimeter of the centrifuge bag. The inner perimeter of the bag defines a central core. The tubes are sandwiched between the upper and lower sheets and extend from the central core of the centrifuge bag. The upper and lower sheets are sealed together at their inner perimeters such that the tubes are sealed between said upper and lower sheets at the inner perimeter. The bag may be used to harvest platelet rich plasma from whole blood in either a batch method or while simultaneously infusing additional aliquots of whole blood into the bag during centrifugation.Type: GrantFiled: May 21, 2009Date of Patent: March 1, 2011Assignee: Arteriocyte Medical Systems, Inc.Inventors: Victor D. Dolecek, David Malcolm
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Patent number: 7883501Abstract: A double syringe delivery system is disclosed for holding a pair of syringes in a manner so as to accommodate the simultaneous activation of the plunger of each syringe in order to effect simultaneous delivery of the contents of each syringe. The delivery system includes a delivery mechanism for delivering the contents of both syringes to a site of application. The delivery system further includes a support member that is positioned between the two syringe bodies. The elongated support member has resilient, C-shaped clamps on one end of the support member. The clamps are designed to be removably clamped onto the applicator so that the syringe barrels will be held together in a parallel manner. The elongated support member further comprises finger grips. A plunger connects the two syringe plungers so that they can also be simultaneously activated.Type: GrantFiled: August 10, 2009Date of Patent: February 8, 2011Assignee: Arteriocyte Medical Systems, Inc.Inventors: Kevin D. McIntosh, Richard M. Albrecht
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Patent number: 7867159Abstract: A centrifugal method, and corresponding system, for processing blood to collect platelet rich plasma. A separation chamber is filled with blood from a fill syringe by rotating the separation chamber at a fill rotation rate and pumping the blood from the fill syringe. A soft spin is used to initially separate red blood cells from platelets by spinning the separation chamber at a soft spin rate. A percentage of the blood is drawn from the separation chamber back into the fill syringe to remove separated red blood cells. A second portion of the separated blood is drawn from the separation chamber until a red blood cell/platelet interface is detected. A hard spin is performed by spinning the separation chamber at a higher rate and connecting tubing is cleared of red blood cells by drawing a predetermined clearing volume. The platelet rich plasma is then collected in the collection syringe.Type: GrantFiled: June 4, 2007Date of Patent: January 11, 2011Assignee: Arteriocyte Medical Systems, Inc.Inventors: Victor D. Dolecek, Gary L. Berg, Kenneth E. Merte, David Malcolm, Kevin D. McIntosh, Vitaly G. Sitko
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Patent number: 7838039Abstract: Provided are methods of applying biological compositions, that is, autologous bioadhesive sealant compositions containing one or more biological agents, to an individual, wherein all the blood components used in preparing the composition are derived from the patient who is to receive the biological composition. In one embodiment, the method comprises obtaining a whole blood sample from an individual; forming an inactive platelet rich plasma from the whole blood sample; mixing a biological agent into the inactive platelet rich plasma; obtaining thrombin from the whole blood sample; mixing the thrombin into the inactive platelet rich plasma to form a biological composition; and applying the biological composition to the individual.Type: GrantFiled: January 27, 2005Date of Patent: November 23, 2010Assignee: Arteriocyte Medical Systems, Inc.Inventors: Robert F. Baugh, Lisa M. Lim, Julie S. Johnston, John G. Rivera
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Patent number: 7811463Abstract: A rotatable rotor for separating components contained in a fluid, comprising an annular base having a first annular channel and an annular cover having a second annular channel for holding a flexible doughnut-shaped centrifuge bag therebetween. The cover has one or more radially spaced apart concentric indicator lines for monitoring the separation of the components. When the base and cover are superimposed, the first and second channels define an annular interior chamber having an off-centered figure eight configuration. The base and cover each comprise a grooved column axially centered and extending from the base top surface and the cover bottom surface, respectively. The flexible bag comprises inner and outer tubes extending from the core of the bag and which are seated in the column grooves to ensure that the bag is fixably rotatable with the rotor.Type: GrantFiled: March 24, 2008Date of Patent: October 12, 2010Assignee: Arteriocyte Medical Systems, Inc.Inventors: Victor D. Dolecek, David Malcolm
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Patent number: 7811607Abstract: The present relates to an autologous bioadhesive sealant composition or fibrin glue prepared by a two-phase method, wherein all of the blood components for the bioadhesive sealant are derived from a patient to whom the bioadhesive sealant will be applied. A platelet rich plasma and a platelet poor plasma are formed by centrifuging a quantity of anticoagulated whole blood that was previously drawn from the patient. In one embodiment, the platelet rich plasma is divided into two portions. In phase one, a compound that reverses the effect of the anticoagulant is added to the first portion and a clot is allowed to form. The clot is then triturated, and the resulting serum containing autologous thrombin is collected. In phase two, the serum obtained from phase one is mixed with the second portion of the platelet rich plasma to form the bioadhesive sealant of the present invention.Type: GrantFiled: December 3, 2004Date of Patent: October 12, 2010Assignee: Arteriocyte Medical Systems, Inc.Inventors: Robert F. Baugh, Lisa M. Lim, Julie S. Johnston, John G. Rivera
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Publication number: 20100076399Abstract: Dispensing assemblies, methods, and kits of parts for dispensing two separate fluids to an treatment site, including entraining non-atomized flow of a first fluid in an atomized flow of a second fluid, delivering a first fluid upstream from a second fluid, delivering a first fluid and a second fluid with re-shapeable malleable tubes, delivering first and second fluids with releasable connectors maintained by a handle assembly, and kits of parts with angularly offset pockets.Type: ApplicationFiled: November 23, 2009Publication date: March 25, 2010Applicant: ARTERIOCYTE MEDICAL SYSTEMS, INC.Inventors: Kevin D. McIntosh, Victor D. Dolecek
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Patent number: 7635343Abstract: Dispensing assemblies, methods, and kits of parts for dispensing two separate fluids to an treatment site, including entraining non-atomized flow of a first fluid in an atomized flow of a second fluid, delivering a first fluid upstream from a second fluid, delivering a first fluid and a second fluid with re-shapeable malleable tubes, delivering first and second fluids with releasable connectors maintained by a handle assembly, and kits of parts with angularly offset pockets.Type: GrantFiled: January 27, 2006Date of Patent: December 22, 2009Assignee: Arteriocyte Medical Systems, Inc.Inventors: Kevin D. McIntosh, Victor D. Dolecek
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Publication number: 20090306623Abstract: A double syringe delivery system is disclosed for holding a pair of syringes in a manner so as to accommodate the simultaneous activation of the plunger of each syringe in order to effect simultaneous delivery of the contents of each syringe. The delivery system includes a delivery mechanism for delivering the contents of both syringes to a site of application. The delivery system further includes a support member that is positioned between the two syringe bodies. The elongated support member has resilient, C-shaped clamps on one end of the support member. The clamps are designed to be removably clamped onto the applicator so that the syringe barrels will be held together in a parallel manner. The elongated support member further comprises finger grips. A plunger connects the two syringe plungers so that they can also be simultaneously activated.Type: ApplicationFiled: August 10, 2009Publication date: December 10, 2009Applicant: ARTERIOCYTE MEDICAL SYSTEMS, INC.Inventors: Kevin D. McIntosh, Richard M. Albrecht
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Patent number: 7604626Abstract: A double syringe delivery system is disclosed for holding a pair of syringes in a manner so as to accommodate the simultaneous activation of the plunger of each syringe in order to effect simultaneous delivery of the contents of each syringe. The delivery system includes a delivery mechanism for delivering the contents of both syringes to a site of application. The delivery system further includes a support member that is positioned between the two syringe bodies. The elongated support member has resilient, C-shaped clamps on one end of the support member. The clamps are designed to be removably clamped onto the applicator so that the syringe barrels will be held together in a parallel manner. The elongated support member further comprises finger grips. A plunger connects the two syringe plungers so that they can also be simultaneously activated.Type: GrantFiled: June 24, 2004Date of Patent: October 20, 2009Assignee: Arteriocyte Medical Systems, Inc.Inventors: Kevin D. McIntosh, Richard M. Albrecht
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Patent number: 7413652Abstract: A system for the production of a blood component composition is provided. The system includes a centrifuge having a blood reservoir for receiving and separating a blood sample into multiple components; a dispenser disposed outside of the centrifuge having a first collection chamber containing an activation agent and a second collection chamber containing one or more medicinal agents; means for removing a first portion at least one separated blood component from the centrifuge to the first container and a second portion to the second collection chamber, wherein the first collection chamber activates the first portion and stores the resulting clot and thrombin; a filter for separating the thrombin from the clot; and a nozzle for entraining and mixing the thrombin with the second portion containing the one or more medicinal components.Type: GrantFiled: April 26, 2005Date of Patent: August 19, 2008Assignee: Arteriocyte Medical Systems, Inc.Inventors: Victor D. Dolecek, Robert F. Baugh, John G. Rivera, William F. McKay, Jeffery C. Marx