Abstract: A double-sided aspheric diffractive multifocal lens and methods of manufacturing and design of such lenses in the field of ophthalmology. The lens can include an optic comprising an aspheric anterior surface and an aspheric posterior surface. On one of the two surfaces a plurality of concentric diffractive multifocal zones can be designed. The other surface can include a toric component. The double-sided aspheric surface design results in improvement of the modulation transfer function (MTF) of the lens-eye combination by aberration reduction and vision contrast enhancement as compared to one-sided aspheric lens. The surface having a plurality of concentric diffractive multifocal zones produces a near focus, an intermediate focus, and a distance focus.

Abstract: Compositions are provided herein comprising a base polymer having engrafted with a secondary polymeric matrix having hydrophilic and lubricious copolymer brushes. Each copolymer brush further comprises functional groups immobilized along the surface of the brush in a plurality of layers, the functional groups conferring hydrophilic and lubricious properties to the base polymer. These polymer compositions are useful for e.g., fabricating devices for delivery of intraocular lenses (IOLs) as well as improving the hydrophilic properties of contact lenses.

Abstract: The present invention provides a device and method for inserting an IOL into an eye of a patient. The IOL injector is configured to automatically load an IOL into the injector by folding and aligning the IOL into a lens cartridge of the injector without manual manipulation of the IOL by the physician during the procedure. The injector is configured to properly orient and align the IOL within the injector and maintain proper alignment throughout delivery of the IOL to the eye of a patient and thereby ensuring that the IOL is properly positioned and oriented at a predetermined location in the eye.

Abstract: Compositions are provided herein comprising a base polymer having engrafted with a secondary polymeric matrix having hydrophilic and lubricious copolymer brushes. Each copolymer brush further comprises functional groups immobilized along the surface of the brush in a plurality of layers, the functional groups conferring hydrophilic and lubricious properties to the base polymer. These polymer compositions are useful for e.g., fabricating devices for delivery of intraocular lenses (IOLs) as well as improving the hydrophilic properties of contact lenses.

Abstract: Compositions are provided herein comprising a base polymer having engrafted with a secondary polymeric matrix having hydrophilic and lubricious copolymer brushes. Each copolymer brush further comprises functional groups immobilized along the surface of the brush in a plurality of layers, the functional groups conferring hydrophilic and lubricious properties to the base polymer. These polymer compositions are useful for e.g., fabricating devices for delivery of intraocular lenses (IOLs) as well as improving the hydrophilic properties of contact lenses.

Abstract: Compositions are provided herein comprising a base polymer having engrafted with a secondary polymeric matrix having hydrophilic and lubricious copolymer brushes. Each copolymer brush further comprises functional groups immobilized along the surface of the brush in a plurality of layers, the functional groups conferring hydrophilic and lubricious properties to the base polymer. These polymer compositions are useful for e.g., fabricating devices for delivery of intraocular lenses (IOLs) as well as improving the hydrophilic properties of contact lenses.

Abstract: Compositions are provided herein comprising a base polymer having engrafted with a secondary polymeric matrix having hydrophilic and lubricious copolymer brushes. Each copolymer brush further comprises functional groups immobilized along the surface of the brush in a plurality of layers, the functional groups conferring hydrophilic and lubricious properties to the base polymer. These polymer compositions are useful for e.g., fabricating devices for delivery of intraocular lenses (IOLs) as well as improving the hydrophilic properties of contact lenses.

Abstract: Compositions are provided herein comprising a base polymer having engrafted with a secondary polymeric matrix having hydrophilic and lubricious copolymer brushes. Each copolymer brush further comprises functional groups immobilized along the surface of the brush in a plurality of layers, the functional groups conferring hydrophilic and lubricious properties to the base polymer. These polymer compositions are useful for e.g., fabricating devices for delivery of intraocular lenses (IOLs) as well as improving the hydrophilic properties of contact lenses.

Abstract: A ceramic composition including a first ceramic material and a second ceramic material that is in the form of nano-, submicron-, or micron-sized particles, in which the first ceramic material has a lower melting point than the second ceramic material, and, when the first ceramic material melts into a liquid and the second ceramic material remains particulate, the second ceramic material floats at the top of the liquid. Also disclosed is a variant of this composition including a first ceramic material and a second ceramic material, in which the second ceramic material has a melting point higher than the first ceramic material, and, when the first ceramic material melts into a liquid, the second ceramic material partially or completely dissolves in the liquid.

Abstract: A ceramic composition including a first ceramic material and a second ceramic material that is in the form of nano-, submicron-, or micron-sized particles, in which the first ceramic material has a lower melting point than the second ceramic material, and, when the first ceramic material melts into a liquid and the second ceramic material remains particulate, the second ceramic material floats at the top of the liquid. Also disclosed is a variant of this composition including a first ceramic material and a second ceramic material, in which the second ceramic material has a melting point higher than the first ceramic material, and, when the first ceramic material melts into a liquid, the second ceramic material partially or completely dissolves in the liquid.

Abstract: This invention relates to a ceramic composite having a ceramic substrate and a ceramic layer disposed on the top surface of the substrate. The layer contains a multiplicity of nano-sized or micron-sized stalagmites, a multiplicity of nano-sized or micron-sized stalactites, a multiplicity of nano-sized or micron-sized columns, or a combination thereof. The invention also relates to a composition for and a method of making the ceramic composite.

Abstract: A device containing a support member, a cross-linked polymer, and a pH buffer agent. A surface of the support member is coated with the cross-linked polymer in which the pH buffer agent is embedded.

Abstract: A method of coating a polymer onto an implant having at least one interstice. The method includes (1) providing a solution containing a polymer; (2) applying the solution onto the implant; (3) and removing the solution spanning the interstice by (a) contacting the outer surface of the implant with a surface of a substrate, so that the solution spanning the interstice is drawn to the surface of the substrate via affinity between them; or by (b) bursting and removing the solution spanning the interstice on the implant with an air pressure difference before drying; and (4) drying the solution to form a coating.

Abstract: A method of preparing a polymeric demulcent-containing ophthalmic composition. The method includes immersing a polymeric demulcent in water or in an aqueous solution containing one or more ingredients, agitating the water or solution at 25 to 45° C. until the polymeric demulcent is dissolved to form a polymeric demulcent-containing solution, and optionally adding one or more other ingredients to the polymeric demulcent-containing solution.

Abstract: An aqueous ophthalmic solution containing 0.2 to 2.5 percent by weight a polymeric demulcent, 0.045 to 0.065 percent by weight a calcium salt, and 0.14 to 1.4 percent by weight a phosphate salt. The solution has a viscosity of 20 to 150 centipoise and is buffered to a pH 5.5 to 8.5.

Abstract: A substrate surface is plasma cleaned and silanized in a chamber. Plasma is generated in the chamber to clean the substrate surface. Gas containing an organosilane compound is introduced into the same chamber to silanized the cleaned surface. Water is deposited on the substrate surface to facilitate silane coupling reaction. A layer of covalently bonded silane molecules having functional groups is thus produced on the substrate surface. The substrate is then cured by a baking process.