Abstract: The invention provides a surgical instrument comprising a handle (1) shaped to enable it to be freely rotated by the user's fingers about its longitudinally axis in the hand of the user, and held by the user at any angle of rotation about its longitudinal axis; the handle (1) having an elongate shaft (2) extending therefrom and a surgical tool (3) mounted on the shaft (2) at a location remote from the handle (1); the handle (1) being provided with actuato means (20, 15, 29) operatively linked through the shaft (2) to the surgical tool (3); the actuator means having an actuator surface (17, 31) or surfaces extending around substantially the entire circumference of the handle (1), whereby the actuator means is operable by applying pressure at substantially any circumferential location on the actuator surface (17, 31) or surfaces, to actuate the surgical tool (3).