Patents Assigned to AUCENTRA HOLDINGS PTY LTD
  • 5-(pyrimidin-4-yl)thiazol-2-yl urea derivatives as therapeutic agents
    Patent number: 11325900
    Abstract: A novel class of inhibitors of protein kinases useful in the treatment of proliferative cell diseases and conditions including cancers, and especially those characterised by over-expression of CDK8 and/or one or more aberrant CDK8 activity, including certain cancers of lung, breast, brain, ovary, prostate, colorectal cancer and leukaemias. The inhibitors have the general structure I.
    Type: Grant
    Filed: January 14, 2019
    Date of Patent: May 10, 2022
    Assignee: AUCENTRA HOLDINGS PTY LTD
    Inventors: Shudong Wang, Stephen Philip, Mingfeng Yu