Abstract: An apparatus for monitoring proteins and cells. The apparatus includes a plate having wells in which cells are disposed. The apparatus includes means for analyzing the effect or proteins and other biological and chemical moieties on the cells. A method for monitoring of proteins and cells. A method for analyzing a cells. An apparatus for aligning light in a well of a plate for holding cells. A method for lighting a well. A method for determining a condition of a cell. An apparatus for indicating a condition of a cell. A method for establishing a focus profile of a plate having wells for holding cells. A method for manipulating cells. An apparatus for manipulating cells.
Type:
Grant
Filed:
October 26, 2001
Date of Patent:
December 14, 2004
Assignee:
Automated Cell, Inc.
Inventors:
Alfred Blalock Bahnson, Douglas J. Koebler, Charalambos N. Arthanassiou, Raymond K. Houck, Kris Sachsenmeier, Lei Qian
Abstract: A method for analyzing a cell or cells by suppressing non-biological movement. The method includes the steps of placing the cell or cells in a solution having a viscosity enhancement medium. There can be the step of measuring the motility of the cell, or other desired attributes of the cell or cells.
Abstract: An apparatus for following cells includes an automated biochamber having a plate with at least one well in which cells are disposed in a controlled environment automatically maintained at desired conditions. The apparatus includes means for tracking individual cells in the well over time. A method for following cells includes the steps of instructing a camera by a computer to take a first image of a first well of a plate. There is the step of taking automatically with the camera the first image of the well at the instruction of the computer at a first-time. There is the step of identifying a first cell in the well with the computer. There is the step of instructing the camera by the computer to take a second image of the well. There is the step of taking automatically with the camera the second image of the well at the instruction of the computer at a second time. There is the step of linking the first cell in the first image to the first cell in the second image.
Type:
Application
Filed:
December 27, 2002
Publication date:
July 1, 2004
Applicant:
Automated Cell, Inc.
Inventors:
Douglas J. Koebler, Charalambos N. Athanassiou, Lei Qian, Aleksandr I. Lisovich
Abstract: An apparatus for monitoring proteins and cells. The apparatus includes a plate having wells in which cells are disposed. The apparatus includes means for analyzing the effect or proteins and other biological and chemical moieties on the cells. A method for monitoring of proteins and cells. A method for analyzing a cells. An apparatus for aligning light in a well of a plate for holding cells. A method for lighting a well. A method for determining a condition of a cell. An apparatus for indicating a condition of a cell. A method for establishing a focus profile of a plate having wells for holding cells. A method for manipulating cells. An apparatus for manipulating cells.
Type:
Application
Filed:
October 26, 2001
Publication date:
May 1, 2003
Applicant:
Automated Cell, Inc.
Inventors:
Alfred Blalock Bahnson, Douglas J. Koebler, Charalambos N. Athanassiou, Raymond K. Houck, Kris F. Sachsenmeier, Lei Qian
Abstract: A method for analyzing a cell or cells by suppressing non-biological movement. The method includes the steps of placing the cell or cells in a solution having a viscosity enhancement medium. There can be the step of measuring the motility of the cell, or other desired attributes of the cell or cells.
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