Abstract: A pharmaceutical or food composition including alverine, 4-hydroxy alverine, a derivative thereof, or a salt thereof and their uses are disclosed. The composition is useful for preventing, alleviating, or treating muscular weakness-related diseases. When myoblasts are treated with the alverine, 4-hydroxy alverine, derivative thereof, or salt thereof, differentiation into myotubes is promoted. Therefore, the alverine, 4-hydroxy alverine, derivative thereof, or salt thereof can be effectively used in the promotion of differentiation of myoblasts and the prevention, alleviation, or treatment of muscular weakness-related diseases.
Type:
Application
Filed:
April 9, 2021
Publication date:
May 18, 2023
Applicant:
AVENTI INC.
Inventors:
Ki-Sun KWON, Younglang LEE, Jong Hyun YOON, Seung-Min LEE, Chang Hoon JEON, Tai Hwan HA, Do Yeun JEONG