Abstract: A system and method for creating a plurality of denaturation curves is disclosed. In accordance with certain embodiments, one variable, such as salt content, pH or another parameter, is varied to create a plurality of different buffer solutions. Each is then used to create a denaturation graph. The plurality of denaturation graphs allows analysis of the effect of that variable on protein stability.
Type:
Grant
Filed:
August 22, 2011
Date of Patent:
May 12, 2015
Assignee:
Avia Biosystems, Inc.
Inventors:
Richard Brown, Burleigh Hutchins, Ernesto Freire