Patents Assigned to AXONGEN AB
  • Publication number: 20100076465
    Abstract: A bioresorbable fibrin-based nerve repair conduit produced from tissue glue is disclosed. The nerve repair conduit may be in the form of a sheet or a tube, and may additionally comprise a serine protease, and/or Factor XIII and/or calcium ions. The serine protease is chosen from the group consisting of trombin, plasmin, elastases, and plasminogen activators, or combinations thereof. The nerve repair conduit may moreover be loaded with Schwann cells and/or Stem cells and/or growth factors, for better nerve regeneration. Further, a method of producing the above-mentioned nerve repair conduit is provided, comprising curing fibrinogen and serine protease containing fluids in the form of a fibrinogen-containing tissue glue, in a mould equipped with a central shaft creating a channel in the nerve repair conduit when removed. Moreover, use of a fibrinogen-based tissue glue for the preparation of a fibrin-based nerve repair conduit is described.
    Type: Application
    Filed: May 15, 2008
    Publication date: March 25, 2010
    Applicant: AXONGEN AB
    Inventors: Mikael Wiberg, Giorgio Terenghi