Abstract: A coupler device for interfacing between a biopsy driver and an intraosseous device includes a drive body having a distal drive receptacle. The drive body is rotatable around a longitudinal axis. The distal drive receptacle is configured to drivably couple to a drive portion of the intraosseous device. A distal coupler portion is coupled to the drive body and is configured to operate a distal latch member. The distal latch member latches the drive body to the intraosseous device when the distal coupler portion is in a distal coupler latch position. The distal coupler portion has a distal housing portion that is movable in either of a distal direction or a proximal direction. The distal coupler portion has a distal release position and a proximal release position. The distal housing portion is configured to move the distal coupler portion to a release position to operate the distal latch member.

Abstract: An apparatus is provided for scoring a treatment location in a vessel. A catheter includes an expandable element or inflatable balloon for achieving dilatation. A scoring element includes an elongated scoring wire having at least one ring for selective positioning over the inflatable balloon, which may then be inflated to provide scoring function in both a longitudinal and transverse direction. A plurality of the rings may be provided, and may be adapted for use with a variety of different sizes or lengths of balloons. Related methods are also disclosed.

Abstract: A guidewire loading system includes a catheter having a catheter body having an internal lumen and a snare. The snare is positioned at least partially within the internal lumen of the catheter body. The snare includes a snare body and a first capture flare extending from a first end of the snare body and configured to receive the guidewire. The catheter body compresses the first capture flare to form a friction grip around the guidewire when the snare, including the first capture flare, and guidewire are pulled at least partially through the internal lumen of the catheter body.

Abstract: A tubing component, and methods of forming, for a particulate material delivery assembly including a particulate delivery device to deliver a mixed particulate solution to a patient. The tubing component includes a material including a material density, and a determined thickness sufficient to shield a delivery line connector of a particulate delivery device from at least 90% of a radiation dose. The delivery line connector is configured to receive the mixed particulate solution from the particulate delivery device of the particulate material delivery assembly, and the determined thickness of the tubing component is calculated based on the material density to achieve shielding of the delivery line connector by the material of at least 90% of the radiation dose. The tubing component includes an integral wall of the delivery line connector, an outer sleeve configured to be removably disposed about the delivery line connector, or combinations thereof.

Abstract: An ultrasonic catheter system includes an ultrasonic transducer configured to deliver ultrasonic vibrational energy when activated. An ultrasonic catheter is coupled to the ultrasonic transducer to receive the ultrasonic vibrational energy. The ultrasonic catheter includes an elongate flexible catheter sheath and a distal end portion having a longitudinal axis. The distal end portion includes a longitudinal pressure sensor and a distal tip element. The longitudinal pressure sensor is configured to generate a catheter longitudinal pressure signal corresponding to a sensed longitudinal pressure encountered by the ultrasonic catheter along the longitudinal axis of the distal end portion.

Abstract: Refreshing stylets, catheter systems, and methods thereof are disclosed. The refreshing stylet can be configured to fit within a lumen of a catheter such as hemodialysis catheter. The refreshing stylet can include an elongated hollow body having a proximal portion coupled to a needleless connector, a distal portion ending in a distal tip, an interior surface, an exterior surface, and a side hole. The exterior surface can be coated with a sustained-release formulation including one or more anti-thrombotic agents. The sustained-release formulation can be configured to contact a luminal surface of the catheter and prevent thrombus formation thereon. The side hole can be configured to provide a locking solution to the lumen of the catheter for locking the catheter between uses.

Abstract: Methods and systems for selection of dosimetry levels and sphere amounts of radioactive compounds for use in a radioembolization procedure for procedure planning may include inputting activity parameter information into a dosimetry portal of a dosimetry selection tool; determining a customized activity based on the activity parameter information and one or more customized activity algorithms; generating one or more sphere amount and dosage recommendations based on the customized activity and one or more dosimetry selection algorithms; selecting one of the one or more sphere amount and dosage recommendations as a selected sphere amount and dosage recommendation; and generating a radioactive compound order for the radioembolization procedure based on the customized activity and the selected sphere amount and dosage recommendation.

Abstract: A thrombi removal catheter includes a sheath having a distal axial opening at a distal end in fluid communication with a lumen, and a lateral opening that extends through a side wall to the lumen. The lateral opening is proximally spaced from the distal end. An elongate member is disposed in the lumen of the sheath and is configured for longitudinal movement relative to the sheath. The elongate member has a proximal position and a distal position relative to the sheath. When the elongate member is in the proximal position, the distal axial opening of the sheath is closed by a distal blocker element of the elongate member and the lateral opening of the sheath is open, and when the elongate member is in the distal position, the lateral opening of the sheath is closed by the proximal blocker element and the distal axial opening of the sheath is open.

Abstract: Systems and methods for detecting an implanted medical device, such as a vascular access port. The implanted medical device may include at least one passive RFID tag that has disposed thereon information about the implanted medical device. The at least one passive RFID tag is designed to be interrogated by a detector associated with an external device, such as an infusion set with an access needle. The interrogating signal induces a return signal from the at least one passive RFID tags. The strength of the return signal may be dependent on the distance and orientation of the tag relative to the detector. The system may be designed to interpret different signal strengths from different RFID tags to guide the needle to a correct insertion position, thereby accessing a port that cannot be readily detected visually or by palpation.

Abstract: A closure device for repairing a vein valve insufficiency includes a tube formed of extracellular matrix including elastin fibers and one or more anchoring elements. The tube is radially expandable from a retracted configuration to an expanded configuration and the tube is naturally biased to the retracted configuration. The one or more anchoring elements anchor the tube to a vessel wall of a vessel upon expansion of the tube to the expanded configuration wherein the tube circumferentially contacts the vessel wall of the vessel and is anchored thereto by the one or more anchoring elements. Retraction of the tube to the retracted configuration draws the vessel wall of the vessel radially inward to repair the vein valve insufficiency.

Abstract: An orbital atherectomy system includes a handheld driver having a motor. An elongate flexible driveshaft has a proximal end portion and a distal end portion. The proximal end portion is drivably coupled to the motor. The distal end portion defines a rotational axis. An abrasive element is fixedly disposed on the distal end portion of the elongate flexible driveshaft. The abrasive element includes a first flat side, a second flat side, a leading tapered end portion having a leading end, and a trailing tapered end portion having a trailing end. The first flat side and the second flat side are on opposite sides of the rotational axis.

Abstract: A biopsy device includes a cutting cannula and an inner member. The inner member has a rotatable toothed rack, a sharpened distal tip, and a sample notch. The inner member is configured to be received in the cutting cannula. The rotatable toothed rack has a proximal portion and a rotation zone in the proximal portion. The rotation zone of the rotatable toothed rack has circumferential toothing configured as a series of longitudinally spaced cut-outs that run around an entire circumference of the rotatable toothed rack to facilitate both a longitudinal movement and a rotational movement of the rotatable toothed rack and inner member. A drive is configured to engage the circumferential toothing to move the rotatable toothed rack within the cutting cannula in at least one of the longitudinal movement and the rotational movement.

Abstract: An access port for providing subcutaneous access to a patient is disclosed. In one embodiment, the port includes an internal body defining a fluid cavity that is accessible via a septum. A compliant outer cover including silicone is disposed about at least a portion of the body. A flange is included with the port body and is covered by the outer cover. The flange radially extends about a perimeter of the port body proximate the septum so as to impede penetration of a needle substantially into the outer cover in instances where the needle misses the septum. The flange can further include both an anchoring feature for securing the outer cover to the port body and an identification feature observable via x-ray imaging technology for conveying information indicative of at least one attribute of the access port. The outer cover provides a suitable surface for application of an antimicrobial/antithrombotic coating.

Abstract: A fistula formation device includes a first engagement member and a second engagement member. The first engagement member is configured to be positioned within a first vessel. The first engagement member includes a plate defining a first opening therethrough. The second engagement member is configured to be positioned within a second vessel. The second engagement member includes a base plate having a second opening extending therethrough, and one or more retention members extending from the base plate around the second opening, wherein the one or more retention members are configured to extend through the plate of the first engagement member to secure the first engagement member to the second engagement member and form an open conduit through the first engagement member and the second engagement member between the first vessel and the second vessel.

Abstract: A vial assembly includes a vial and a needle with at least one port. The vial includes a particulate material, a septum, a neck region including a first width, and a particulate region including a second width greater than the first width. The vial assembly is configured to move to a locked position. The needle may be configured to puncture the septum with the at least one port configured to be in the neck region when in the locked position. The at least one port may be configured to inject a fluid into the vial assembly to mix with the particulate material upon actuation of a vial engagement mechanism in a first direction and to receive a resulting mixed fluid from the vial assembly upon actuation of the vial engagement mechanism in a second direction opposite the first direction.

Abstract: An implant device to facilitate access across pleura layers includes a tube having a side wall, a lumen, a proximal end portion, a distal end portion, and a central portion interposed between the proximal end portion and the distal end portion. The tube has a longitudinal extent, wherein each of the proximal end portion and the distal end portion extends outwardly from the central portion, and wherein the side wall has a longitudinal split to define a first lateral edge surface and a second lateral edge surface. Each of the first lateral edge surface and the second lateral edge surface longitudinally extends through each of the proximal end portion, the central portion, and the distal end portion.

Abstract: An electromagnetic tracking sensor for use in a medical device includes a flexible hollow cylinder core having an interior surface and an exterior surface. The flexible hollow cylinder core has a magnetic material layer attached to the interior surface of the flexible hollow cylinder core. A wire coil is adjacent to, and circumferentially surrounds, the exterior surface of the flexible hollow cylinder core.