Abstract: The present invention relates generally to the field of molecular biology and to the methods for enhancing various economically important yield-related traits in plants. More specifically, the present invention relates to a method for enhancing yield-related traits in plants by modulating expression of a nucleic acid encoding an OsRSZ33 RRM polypeptide or a growth-related protein (GRP) having at least 25% amino acid sequence identity to SEQ ID NO:251 or a ZPR polypeptide. The present invention also relates to plants having modulated expression of a nucleic acid encoding an OsRSZ33 RRM polypeptide or a growth-related polypeptide as defined herein or a ZPR polypeptide. Such plants have enhanced yield-related traits relative to controls. The invention also provides hitherto unknown OsRSZ33 RRM-encoding nucleic acids or GRP-encoding nucleic acids or a ZPR polypeptide, and constructs comprising the same, which are useful in performing the methods of the invention.