Abstract: The invention relates to the field of blood coagulation. Novel oxazolidinone derivatives of the general formula (I) processes for their preparation and their use as medicinally active compounds for the prophylaxis and/or treatment of disorders are described.
Type:
Application
Filed:
February 7, 2008
Publication date:
August 21, 2008
Applicant:
Bayer Healthcare Aktiengesellschaft
Inventors:
Alexander Straub, Thomas Lampe, Jens Pohlmann, Susanne Rohrig, Elisabeth Perzborn, Karl-Heinz Schlemmer, Joseph Pernerstorfer
Abstract: The present invention relates to an orally administrable preparation comprising a quinolone antibiotic which releases the active compound with a delay.
Type:
Application
Filed:
June 14, 2007
Publication date:
October 11, 2007
Applicant:
Bayer Healthcare Aktiengesellschaft
Inventors:
Venkata-Rangarao Kanikanti, Roland Rupp, Wolfgang Weber, Peter Deuringer, Jan-Olav Henck, Heino Stass, Takaaki Nishioka, Yoshifumi Katakawa, Chika Taniguchi, Hitoshi Ichihashi
Abstract: The present invention relates to a novel process for preparing 8-methoxy-3-quinolonecarboxylic acids which are antibiotics having potent antibacterial action.
Type:
Grant
Filed:
May 11, 2005
Date of Patent:
October 3, 2006
Assignee:
Bayer Healthcare Aktiengesellschaft
Inventors:
Reinhold Gehring, Klaus Mohrs, Werner Heilmann, Herbert Diehl
Abstract: The invention relates to a method for the production of 2-phenyl-substituted imidazotriazinones of general formula (I), comprising the reaction of compounds of formula (II) with compounds of formula (III) and subsequent reaction with iodine or bromine, then with a metal cyanide and reaction with an acid.
Abstract: The present invention relates to a process for the preparation of sulphonamide-substituted imidazotriazinones of the general formula (I) characterized in that compounds of the formula (II) are reacted with sulphuric acid and the products obtained are then reacted with thionyl chloride and converted in situ in an inert solvent using an amine into the compounds according to the invention and, if appropriate, reacted to give the corresponding salts, hydrates or N-oxides.
Type:
Grant
Filed:
May 5, 2005
Date of Patent:
February 14, 2006
Assignee:
Bayer HealthCare Aktiengesellschaft
Inventors:
Marc Nowakowski, Reinhold Gehring, Werner Heilmann, Karl-Heinz Wahl
Abstract: The invention relates to a fluorescence-measuring system as can be employed for high-throughput screening in drug development. The arrangement for fluorescence excitation contains a two-dimensionally extended sample-receiving device and at least two illumination sources for exciting the fluorescence of the samples. The illumination sources are extended linearly and arranged in such a way that the illuminated area of the sample-receiving device is homogeneously illuminated directly or via deflecting mirrors at an opening angle of ?30°.
Abstract: The present invention relates to a novel process for preparing 8-methoxy-3-quinolonecarboxylic acids which are antibiotics having potent antibacterial action.
Type:
Application
Filed:
May 11, 2005
Publication date:
September 22, 2005
Applicant:
Bayer Healthcare Aktiengesellschaft
Inventors:
Reinhold Gehring, Klaus Mohrs, Werner Heilmann, Herbert Deihl
Abstract: The present invention relates to a process for the preparation of sulphonamide-substituted imidazotriazinones of the general formula (I) characterized in that compounds of the formula (II) are reacted with sulphuric acid and the products obtained are then reacted with thionyl chloride and converted in situ in an inert solvent using an amine into the compounds according to the invention and, if appropriate, reacted to give the corresponding salts, hydrates or N-oxides.
Type:
Application
Filed:
May 5, 2005
Publication date:
September 15, 2005
Applicant:
Bayer HealthCare Aktiengesellschaft
Inventors:
Marc Nowakowski, Reinhold Gehring, Werner Heilmann, Karl-Heinz Wahl
Abstract: The present invention relates to a novel process for preparing 8-methoxy-3-quinolonecarboxylic acids which are antibiotics having potent antibacterial action.
Type:
Grant
Filed:
April 3, 2003
Date of Patent:
May 24, 2005
Assignee:
Bayer HealthCare Aktiengesellschaft
Inventors:
Reinhold Gehring, Klaus Mohrs, Werner Heilmann, Herbert Diehl