Abstract: The present invention relates to amino-substituted imidazopyridazine compounds of general formula (I): in which A, R1, R3 and n are as defined in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients.
Type:
Grant
Filed:
September 5, 2012
Date of Patent:
November 22, 2016
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Knut Eis, Florian Puehler, Ludwig Zorn, Arne Scholz, Philip Lienau, Mark Jean Gnoth, Ulf Bömer, Judith Günther, Marion Hitchcock
Abstract: The invention relates to AKR1C3 inhibitors and to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular bleeding disorders and endometriosis.
Abstract: The present invention relates to an insecticide-containing fabric containing at least one embedded insecticidally active ingredient in the polymeric matrix and having excellent wash resistance, and also to the products produced from this fabric and to their use for protecting humans, animals and plants against arthropods, particularly for controlling insects.
Type:
Grant
Filed:
October 14, 2014
Date of Patent:
November 8, 2016
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Rainer Sonneck, Thomas Böcker, Karin Horn, Guenther Nentwig, Maren Heinemann, Thomas König
Abstract: The present application relates to the use of 3-(2,4,6-trimethylphenyl)-4-neopentyl-carbonyloxy-5,5-tetramethylene-?3-dihydrofuran-2-one for controlling insects from the family Psyllidae (psyllids).
Type:
Grant
Filed:
June 23, 2005
Date of Patent:
November 1, 2016
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Thomas Bretschneider, Reiner Fischer, Ernst Brück
Abstract: The present invention relates to cyanoenamine derivatives, their process of preparation, intermediate compounds, their use as fungicide active agents, particularly in the form of fungicide compositions, and methods for the control of phytopathogenic fungi, notably of plants and in material protection, using these compounds or compositions.
Type:
Grant
Filed:
November 11, 2011
Date of Patent:
October 25, 2016
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Jürgen Benting, Ulrike Wachendorff-Neumann, Philippe Desbordes, Christophe Dubost, Pierre Genix, Shinichi Narabu, Jean-Pierre Vors
Abstract: The present invention relates to combinations of A) oxazolidinones of the formula (I) with B) acetylsalicylic acid (aspirin) and C) an ADP receptor antagonist, in particular P2Y12 purinoreceptor blocker, to a process for producing these combinations and to the use thereof as medicaments, in particular for the prophylaxis and/or treatment of thromboembolic disorders.
Abstract: The present invention relates to N-cycloalkyl-N-bicyclicmethylene-carboxamide or thiocarboxamide derivatives, their process of preparation, preparation of intermediate compounds, their use as fungicide active agents, particularly in the form of fungicide compositions, and methods for the control of phytopathogenic fungi, notably of plants, using these compounds or compositions.
Type:
Grant
Filed:
March 25, 2013
Date of Patent:
October 18, 2016
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Jurgen Benting, Peter Dahmen, Philippe Desbordes, Stephanie Gary, Helene Lachaise, Philippe Rinolfi, Ulrike Wachendorff-Neumann
Abstract: The present invention relates to imidazopyrazine compounds of general Formula (I): in which X, R1, R2, R3a, R3b, R4a, R4b, R4C, and R4D are as given in the description and in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds, to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, as well as to intermediate compounds useful in the preparation of said compounds.
Type:
Grant
Filed:
March 16, 2011
Date of Patent:
October 18, 2016
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Ulrich Klar, Marcus Koppitz, Dirk Kosemund, Rolf Bohlmann, Benjamin Bader, Philip Lienau, Gerhard Siemeister, Stefan Prechtl, Duy Nguyen, William Scott
Abstract: Counterflow burner having a combustion chamber (5) to which combustible gas (B) and an oxidising agent (0) can be fed from opposite sides, having three planar substrates (1, 2, 3) which are interconnected, lying one above the other, the middle substrate (2) having the combustion chamber (5), from which passages (4), lying in the plane of the substrate, lead to the edge, the upper substrate (3) and the lower substrate (1) being closed, and at least the middle substrate (2) is produced using methods of microsystem technology.
Abstract: The present invention relates to a process for preparing 4-(4-[({[4-chloro-3-(trifluoromethyl)-phenyl]amino}carbonyl)amino]-3-fluorophenoxy)-N-methylpyridine-2-carboxamide, its salts and monohydrate.
Type:
Grant
Filed:
April 15, 2014
Date of Patent:
October 4, 2016
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Juergen Stiehl, Werner Heilmann, Michael Lögers, Joachim Rehse, Michael Gottfried, Saskia Wichmann
Abstract: The invention relates to a dosing dispenser having a dosing piston, for dosing formulations of a drug or nutritional supplement in the form of a free-flowing bulk material having a particle diameter in the range of 100-1000 ?m.
Type:
Grant
Filed:
March 15, 2013
Date of Patent:
September 27, 2016
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Uwe Müller, Sölen Siemers, Wolfgang Wiehl, Sabine Göttke
Abstract: The present application relates to the use of heterocyclic compounds, some of which are known, for controlling animal pests, including arthropods and in particular insects, furthermore to novel heterocyclic compounds and to processes for their preparation.
Type:
Grant
Filed:
July 9, 2014
Date of Patent:
September 27, 2016
Assignee:
Bayer Intellectual Property GmbH
Inventors:
Thomas Bretschneider, Eva-Maria Franken, Ulrich Görgens, Martin Füsslein, Achim Hense, Joachim Kluth, Hans-Georg Schwarz, Adeline Köhler, Olga Malsam, Arnd Voerste, Angela Becker
Abstract: The present invention relates to compositions for pest control, more particularly insecticides, to a process for preparing them, and to the use of such formulations for sustained control of animal pests (arthropods) on various surfaces. The present invention further relates to active ingredient-wax particles in which at least one active insecticidal ingredient is dispersed in wax.
Type:
Grant
Filed:
December 19, 2011
Date of Patent:
September 27, 2016
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Volker Gutsmann, Thomas Bocker, Guenther Nentwig, Rainer Sonneck, Beate Hack, Daniel Gordon Duff
Abstract: A process for the preparation of the calcium complex of 10-(2, 3-Dihydroxy-1-(hydroxymethyl)propyl)-1,4,7,10-tetraazacyclodecane-4,7-triacetic acid, also known as Calcobutrol, starting from the pure gadolinium complex (Gadobutrol) is disclosed. Also disclosed is Calcobutrol with a hitherto unknown level of purity.
Abstract: The novel active compound combinations comprising 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-[1,2,4]-triazole-3-thione of the formula and the active compound of groups (1) to (24) listed in the description have very good fungicidal properties.
Type:
Grant
Filed:
August 25, 2014
Date of Patent:
September 20, 2016
Assignee:
Bayer Intellectual Property GmbH
Inventors:
Stefan Dutzmann, Klaus Stenzel, Manfred Jautelat
Abstract: A composition comprising at least a pyridylethylbenzamide derivative of general formula (I)(a) and a compound capable of inhibiting the transport of electrons of the respiratory chain in phytopathogenic fungal organisms (b) in an (a)/(b) weight ratio of from 0.01 to 20. A composition further comprising an additional fungicidal compound. A method for preventively or curatively combating the phytopathogenic fungi of crops by using this composition.
Type:
Grant
Filed:
July 26, 2010
Date of Patent:
September 20, 2016
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Jean-Marie Gouot, Marie-Claire Grosjean-Cournoyer
Abstract: The present application relates to novel 3-phenylpropionic acid derivatives which carry a branched or cyclic alkyl substituent in the 3-position, to processes for their preparation, to their use for the treatment and/or prevention of diseases and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular diseases.
Type:
Application
Filed:
May 18, 2016
Publication date:
September 15, 2016
Applicant:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Michael HAHN, Thomas LAMPE, Johannes-Peter STASCH, Karl-Heinz SCHLEMMER, Frank WUNDER, Volkhart Min-Jian LI, Eva-Maria BECKER, Friederike STOLL, Andreas KNORR, Elisabeth WOLTERING
Abstract: A compound of general formula (I): A process for preparing this compound. A fungicidal composition comprising a compound of general formula (I). A method for treating plants by applying a compound of general formula (I) or a composition comprising it.
Type:
Grant
Filed:
November 21, 2006
Date of Patent:
September 13, 2016
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Darren Mansfield, Pierre-Yves Coqueron, Heiko Rieck, Philippe Desbordes, Alain Villier, Marie-Claire Grosjean-Cournoyer, Pierre Genix
Abstract: The invention relates to substituted imidazo-, pyrazolopyrazines and imidazotriazines and processes for their preparation, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, in particular of hematological disorders, preferably of leukopenias and neutropenias.
Type:
Grant
Filed:
May 30, 2013
Date of Patent:
September 6, 2016
Assignee:
Bayer Intellectual Property GmbH
Inventors:
Stephan Siegel, Andreas Wilmen, Susanne Röhrig, Niels Svenstrup, Mark Jean Gnoth, Stefan Heitmeier, Ulrich Rester, Adrian Tersteegen, Michael Gerisch
Abstract: The present invention relates to active compound combinations and compostions for reducing the damage of plants and plant parts as well as losses in harvested fruits or vegetables caused by insects, nematodes or phytopathogens and which have fungicidal or nematicidal or insecticidal activity including any combination of the three activities, in particular within a composition, which comprises (A) Fluopyram, (B) a spore-forming bacterium of the genera Bacillus, selected from Bacillus firmus, Bacillus cereus, Bacillus pumilis, Bacillus amyloliquefaciens, Bacillus subtilis strain GB03, Bacillus subtilis strain QST713, and (C) at least one biological control agent, in particular bacteria, fungi or yeasts, protozoa, viruses, entomopathogenic nematodes, inoculants, botanicals and products produced by microorganisms including proteins or secondary to metabolites.