Patents Assigned to Becton, Dickinson & Company
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Patent number: 11935638Abstract: Devices, systems and methods are provided to securely and wirelessly connect a medical device to a controller or smartphone with medical device control app, and to wirelessly connect the controller or smartphone with medical device control app to other devices providing additional integrated disease management (IDM) functions. At least two different wireless communication protocols are used depending on level of security needed, with greater security needed for exchange of medical device control operation commands and related data between the medical device and its controller or smartphone with medical device control app to avoid nefarious or unintended changes in medical device control. Exchanges of historical data or notifications relating to the medical device and requiring less security can be transmitted to the controller and/or the smartphone or other IDM devices using a different and more commonly used wireless communication protocol that may afford less security.Type: GrantFiled: December 20, 2019Date of Patent: March 19, 2024Assignee: Becton, Dickinson and CompanyInventor: Tony Hai Nguyen
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Patent number: 11935629Abstract: Aspects of the present disclosure include methods for identifying a set of fluorophore-biomolecule reagent pairs for characterizing a sample by flow cytometry. Methods according to certain embodiments include calculating a spectral spillover spreading parameter for a plurality of fluorophores, pairing each fluorophore with a biomolecule that is specific for a biomarker of a cell in the sample to generate a plurality of fluorophore-biomolecule reagent pairs, generating an adjusted spillover spreading matrix for the fluorophore-biomolecule reagent pairs based on the spectral spillover spreading parameter of each fluorophore and a biomarker classification parameter and identifying an optimal set of fluorophore-biomolecule reagent pairs based on the calculated spillover spreading values from the adjusted spillover spreading matrix. Systems and non-transitory computer readable storage medium for practicing the subject methods are also provided.Type: GrantFiled: August 19, 2021Date of Patent: March 19, 2024Assignee: Becton, Dickinson and CompanyInventors: Howard Ray Seay, Aaron Ross, Rane Fields, Peter Mage, Rick Hou
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Patent number: 11931148Abstract: A catheter system may include a catheter assembly, which may include a catheter adapter and a catheter extending distally from a distal end of the catheter adapter. The catheter system may also include a needle assembly, which may include a needle hub and an introducer needle. The needle hub may include: a distal end coupled to the proximal end of the catheter adapter; a proximal end; a wall disposed between the distal end of the needle hub and the proximal end of the needle hub; and a flashback chamber proximate the wall. The introducer needle may be press-fit within a through-hole of the wall. The catheter system may also include a plug coupled to the proximal end of the needle hub. A blood collection device may be coupled to a proximal end of the plug to collect blood from a patient.Type: GrantFiled: August 19, 2020Date of Patent: March 19, 2024Assignee: Becton, Dickinson and CompanyInventors: Linda Kunardi, Kiat Jin Cheng
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Patent number: 11932901Abstract: Disclosed herein include systems, methods, compositions, and kits for performing targeted single cell mRNA sequencing assays. Capture oligonucleotides capable of specifically binding to target nucleic acid species are provided in some embodiments. Depletion oligonucleotides capable of specifically binding to undesirable nucleic acid species are provided in some embodiments. The method can comprise random priming and extension of barcoded transcripts followed by one or more enrichment and/or depletion steps using said capture oligonucleotides and/or depletion oligonucleotides. Immune repertoire profiling methods are also provided in some embodiments.Type: GrantFiled: July 12, 2021Date of Patent: March 19, 2024Assignee: Becton, Dickinson and CompanyInventors: Hye-Won Song, Margaret Nakamoto
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Patent number: 11932849Abstract: Disclosed herein include systems, methods, compositions, and kits for whole transcriptome analysis (WTA) with random priming and extension (RPE). The RPE-based WTA method can comprise hybridizing random primers with a plurality of first strand barcoded polynucleotides associated with a solid support and extending the random primers to generate a plurality of extension products. The method can comprise amplifying the plurality of extension products to generate a sequencing library.Type: GrantFiled: November 7, 2019Date of Patent: March 19, 2024Assignee: Becton, Dickinson and CompanyInventor: Eleen Shum
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Publication number: 20240085285Abstract: Methods for preparing a biological sample for testing by Maldi where such methods are selected based on sample parameters. Maldi scores are obtained for a range of sample parameters (e.g. McFarland, dispense volume and number of dispenses). From the data, sample preparation parameters can be selected for a biological sample being prepared for Maldi testing. One sample preparation strategy uses multiple dispenses of sample with an intervening drying step, which yields more accurate Maldi scores, particularly for samples at the low range of McFarland values (e.g. below about 2).Type: ApplicationFiled: August 21, 2023Publication date: March 14, 2024Applicant: BECTON, DICKINSON AND COMPANYInventors: Timothy Wiles, John D. Mantlo
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Publication number: 20240082482Abstract: A pressure switch is provided and includes an elastic membrane disposed such that pressure from fluid within a fluid path deforms the elastic membrane toward a plunger, thereby moving the plunger. The plunger is disposed between the membrane and an upper plate and is moveable along an axis extending between the membrane and the upper plate. A threshold pressure on the membrane from the fluid within the fluid path deforms the membrane, thereby moving the plunger toward the upper plate.Type: ApplicationFiled: January 27, 2022Publication date: March 14, 2024Applicant: Becton, Dickinson and CompanyInventors: Andrew J. BEAUPRE, Scott STEWART
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Publication number: 20240085446Abstract: An automated analyzer that receives samples prepared for analysis in an automated pre-analytical module and a method of operation of such automated analyzer. The automated analyzer includes a shuttle transfer station that receives a shuttle carrier from the automated pre-analytical system. The shuttle transfer station has a clamping assembly for the shuttle. The clamping assembly has jaws that advance engagement members into contact with a bottom portion of sample containers disposed in the shuttle. The clamping assembly secures the sample containers in the shuttle when sample is aspirated from the sample containers. The automated analyzer also has a multichannel puncture tool that is adapted to be carried by a robotic gripper mechanism. The multichannel puncture tool has multiple puncture members that each defines a channel Each channel is in communication with a different trough in the consumable. A pipette can pass through the channel in the puncture tool.Type: ApplicationFiled: July 25, 2023Publication date: March 14, 2024Applicant: BECTON, DICKINSON AND COMPANYInventors: Michael T. VanSickler, Neil G. Terry, Brian Bell, Steven C. Rotundo, Stephen Robert LaChance, Alyssa Shedlosky
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Publication number: 20240082562Abstract: A disinfection tip is described for disinfecting a threaded connector of a syringe.Type: ApplicationFiled: November 22, 2023Publication date: March 14, 2024Applicant: Becton, Dickinson and CompanyInventor: Kevin M. Ryan
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Patent number: 11925787Abstract: A system may include a flow sensor and a base. The flow sensor may be configured to connect to the base. The flow sensor may include a flow tube including a fluid inlet at a first end of the flow tube, a fluid outlet at a second end of the flow tube opposite the first end of the flow tube, and a fluid injection port between the first end and the second end of the flow tube. The base may include a short range wireless communication device including a curved coil antenna.Type: GrantFiled: January 27, 2021Date of Patent: March 12, 2024Assignee: Becton, Dickinson and CompanyInventors: Gary Ellerbusch, Hong Zhu
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Patent number: 11925783Abstract: A priming assembly for a drug delivery device includes a hub, a base connected to the hub and moveable relative to the hub between a first position and a second position, with the base defining a passageway, a cap defining an interior chamber and a passageway in fluid communication with the interior chamber, and a needle connected to the hub and positioned within the interior chamber of the cap, where the passageway of the base is in fluid communication with the passageway of the cap when the base is in the first position, and where the passageway of the base is isolated from the passageway of the cap when the base is in the second position.Type: GrantFiled: October 7, 2021Date of Patent: March 12, 2024Assignee: Becton, Dickinson and CompanyInventor: Christina Rabolli
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Patent number: 11927522Abstract: Aspects of the present disclosure include methods for adjusting a particle classification index in response to one or more saturated data signals from light detected from particles in a flow stream. Methods according to certain embodiments include detecting light from particles in a flow stream; generating a plurality of data signals from the detected light; identifying one or more saturated data signals; generating a saturated signal index that corresponds to the identified saturated data signals; and applying the saturated signal index to a particle classification index to generate an adjusted particle classification index. In some embodiments, methods include determining one or more parameters of a particle (e.g., for use in a particle sort decision) by calculating an adjusted spectral unmixing matrix for the fluorescence of the particle that excludes one or more saturated data signals. Systems and integrated circuit devices (e.g.Type: GrantFiled: January 28, 2021Date of Patent: March 12, 2024Assignee: BECTON, DICKINSON AND COMPANYInventors: David A. Roberts, Lingjie Wei, Peter Mage
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Patent number: 11927467Abstract: A flow sensor sub-assembly for sensing flow of a fluidic medicament includes a flow tube having an inlet and an outlet, a first coupler secured to the inlet of the flow tube, a second coupler secured to the outlet of the flow tube, a first piezo element secured to the first coupler, a second piezo element secured to the second coupler to define a predetermined distance between the first piezo element and the second piezo element, and at least one absorber sleeve engaged with the first coupler, the flow tube, and the second coupler.Type: GrantFiled: January 21, 2021Date of Patent: March 12, 2024Assignee: Becton, Dickinson and CompanyInventor: Kaushal Verma
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Patent number: 11918796Abstract: A syringe adapter includes a housing having a first end and a second end positioned opposite the first end, with the housing defining a passageway, and a connector body having a first end and a second end positioned opposite the first end, with the connector body having a connection member configured to be secured to a mating connector. One of the housing and the connector body includes a tab and the other of the housing and the connector body defines a channel that receives the tab, with the connector body movable relative to the housing between a first position where the connector body is restricted from rotating relative to the housing in a first rotational direction and free to rotate relative to the housing in a second rotational direction, and a second position where the connector body is free to rotate in the first and second rotational directions.Type: GrantFiled: May 21, 2021Date of Patent: March 5, 2024Assignee: Becton Dickinson and Company LimitedInventors: Jayeon Kim, Christopher Lee
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Publication number: 20240066216Abstract: A fluid delivery device has a syringe barrel with reservoir chamber for fluid, a plunger that translates along a longitudinal axis to expel fluid, and a pusher dimensioned to translate within the barrel and coupled to a drive mechanism to controllably contact and move the plunger. The pusher contacts the plunger at its mechanical center to reduce tilt in the plunger. Contact faces of the pusher and plunger cooperate as a ball joint to minimize non-axial forces on the plunger face. The pusher can have a protrusion of various lengths extending toward and being at least partially received in a recess of various depths in the plunger. The pusher is rigidly connected to a drive mechanism for anti-rotation. The pusher can have scalloped edges for air venting, and apertures for cooperating with protrusions on the drive mechanism to prevent bottoming out the plunger when filling.Type: ApplicationFiled: December 28, 2021Publication date: February 29, 2024Applicant: Becton, Dickinson and CompanyInventors: Alessandro PIZZOCHERO, Mark WOOD, Nicholas ANDERSON
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Publication number: 20240066204Abstract: A transportation tray to transport filled syringes, the tray including a front shelf spaced apart from a rear shelf, with the front shelf and the rear shelf being on approximately the same plane. The front shelf includes at least one set of paired flexible fingers, the paired flexible fingers being spaced apart sufficiently to accommodate a barrel of a syringe and to thus hold the syringe on the tray.Type: ApplicationFiled: January 12, 2022Publication date: February 29, 2024Applicant: Becton, Dickinson and CompanyInventor: Tianqi HANG
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Patent number: 11913083Abstract: A real time Taq-Man PCR assay for detecting multiple serotypes of human papillomavirus (HPV) wherein the number of serotypes detected exceeds the number of colorimetric channels for detection. A biological sample is combined with three oligonucleotide primer/probe sets such that the probes and primers anneal to a target sequence. Each primer/probe set is at least preferential for a specific serotype of an organism. The first and second primer/probe sets are degenerate with respect to each other. The third primer/probe set is not degenerate with respect to the first and second primer/probe sets and discriminates for a third serotype. The third primer/probe set has a signal moiety that emits signal at a wavelength that is the same or different from the wavelength emitted by the signal moiety of the degenerate primer/probe set probes. The target sequences, if present, are amplified and detected.Type: GrantFiled: November 11, 2020Date of Patent: February 27, 2024Assignee: Becton, Dickinson and CompanyInventors: Chi Chen, Hugh J. Peck, Michael Porter, Gregory A. Richart, Ray A. McMillian
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Patent number: 11912876Abstract: Water solvated polymeric dyes and polymeric tandem dyes having a blue excitation spectrum are provided. The polymeric dyes are conjugated polymers that can include a thiophene-containing co-monomer. The polymeric tandem dyes further include a signaling chromophore covalently linked to the conjugated polymer in energy-receiving proximity therewith. Also provided are labelled specific binding members that include the subject polymeric dyes. Methods of evaluating a sample for the presence of a target analyte and methods of labelling a target molecule in which the subject polymeric dyes find use are also provided. Systems and kits for practicing the subject methods are also provided.Type: GrantFiled: December 18, 2020Date of Patent: February 27, 2024Assignee: BECTON, DICKINSON AND COMPANYInventors: Yongchao Liang, Haiqing Li, Brent S. Gaylord
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Patent number: 11911586Abstract: Disinfection cap includes housing comprising closed top, essentially cylindrical sidewall, and open bottom formed by the sidewall with opening to inner cavity within the housing for receiving tip including mating feature of needleless connector. Disinfection sponge can be configured within inner cavity, removable cover sealing opening to inner cavity to seal sponge within inner cavity prior to cap use. Inner cavity includes at least one thread on inner surface of its sidewall that does not correspond to the mating feature of needleless connector, but is sufficient to interlock with mating feature of needleless connector. Plurality of disinfection caps are disposed on strip of IV pole hanging device such that each cap can be peeled off the strip unsealed for immediate use, or separated from the strip sealed for later use.Type: GrantFiled: August 6, 2021Date of Patent: February 27, 2024Assignee: Becton, Dickinson and CompanyInventors: Kevin M. Ryan, Nichola Charles
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Patent number: D1017066Type: GrantFiled: October 1, 2021Date of Patent: March 5, 2024Assignee: Becton, Dickinson and CompanyInventors: Adam Steel, Alyssa Shedlosky, Ammon David Lentz