Patents Assigned to Behringwerke Aktiengellschaft
  • Tetravalent bispecific receptors, the preparation and use thereof
    Patent number: 5959083
    Abstract: The invention relates to bispecific tetravalent receptors of the formula I ##STR1## or formula II ##STR2## against a tumor-associated antigen and against an agent active against tumors.
    Type: Grant
    Filed: September 21, 1994
    Date of Patent: September 28, 1999
    Assignee: Behringwerke Aktiengellschaft
    Inventors: Klaus Bosslet, Gerhard Seemann
  • Oligopeptidylargininol derivatives and their homologs, a process for their preparation, their use and agents containing them
    Patent number: 4713369
    Abstract: The invention relates to new peptidylargininol derivatives and their homologs of the general formulaX-D-Phe-Pro-A-Y.(HB).sub.n,X being a hydrogen atom or a known protective group customary in peptide chemistry,D-Phe being D-phenylalanine,Pro being L-proline,A being a .omega.-guanidiano-.beta.-aminoalkanol residue of the formula --NHCH (CH.sub.2).sub.m NHC(NH)NH.sub.2 CH.sub.2 O, with m being 2 to 5, preferably an argininol residue or a homoargininol residue,Y being a hydrogen atom or an ester-forming group,B being an acid residue, andn being 0, 1 or 2,and to a process for the preparation of these compounds, to pharmaceutical agents containing these compounds, and to the use of these agents as thrombin inhibitors.
    Type: Grant
    Filed: February 14, 1986
    Date of Patent: December 15, 1987
    Assignee: Behringwerke Aktiengellschaft
    Inventor: Werner Stuber