Abstract: Described are methods for providing a pulsed dose of a gaseous drug over a portion of total inspiratory time, where the dose of the gaseous drug is delivered at a concentration of nL of gaseous drug per mL tidal volume.
Abstract: The present disclosure relates to use of pulsed dose inhaled nitric oxide for treatment of infection, including infection with SARS-CoV2 and the disease state COVID-19.
Abstract: Described are methods for improving oxygen saturation in patients suffering from hypoxemia, wherein said patients are receiving a continuous flow of oxygen at 10 L/min and exhibit an initial oxygen saturation of at least about 88%, comprising administering inhaled nitric oxide to said patients in an outpatient setting. Methods for improving quality of life for a hospitalized patient, reducing patient hospitalization time, and reducing costs associated with patient hospitalization are also described.
Abstract: Described are methods for reducing pulmonary resistance, reducing pulmonary pressure, and increasing pulmonary arterial compliance by providing a inhaled nitric oxide.
Abstract: Described are methods for providing a pulsed dose of nitric oxide during at least the first two-thirds of total inspiratory time in each single breath for a therapeutically relevant period of time.
Type:
Application
Filed:
May 17, 2019
Publication date:
July 22, 2021
Applicant:
BELLEROPHON THERAPEUTICS
Inventors:
Parag SHAH, Martin DEKKER, William LEONARD, Donatas ZUZEVICIUS