Abstract: Disclosed is a scaffold for living donor transplantation, which includes sintered bioglass and a biocompatible polymer and has improved properties using a 3D printer through a fused deposition modeling process.
Type:
Grant
Filed:
December 11, 2019
Date of Patent:
May 4, 2021
Assignees:
CG BIO CO., LTD., BIOALPHA INC.
Inventors:
Jun Young Lim, Yong Bok Kim, Hyun Seung Ryu
Abstract: The present invention relates to a carrier for growth factor related to regeneration of bone tissues that is capable of arbitrarily controlling the delivery rate of growth factors related to bone regeneration and thus especially applicable to a bone void filler in the fields of the dental or orthopedic applications. The carrier for controlling the delivery rate of the growth factor in the present invention is composed of a hyaluronic acid hydrogel having a distribution of interconnected pores and a calcium phosphate microsphere being distributed in the pores of the hyaluronic acid hydrogel. The calcium phosphate microsphere having a porosity suitable for delivery of the growth factor is positioned into the pores of the cross-linked hyaluronic acid hydrogel to complete the carrier.
Type:
Grant
Filed:
January 9, 2017
Date of Patent:
March 27, 2018
Assignee:
Bioalpha Inc.
Inventors:
Jung Ju Kim, Su Hyun Jung, Hyun Seung Ryu, Jun Hyuk Seo
Abstract: The present invention relates to a carrier for growth factor related to regeneration of bone tissues that is capable of arbitrarily controlling the delivery rate of growth factors related to bone regeneration and thus especially applicable to a bone void filler in the fields of the dental or orthopedic applications. The carrier for controlling the delivery rate of the growth factor in the present invention is composed of a hyaluronic acid hydrogel having a distribution of interconnected pores and a calcium phosphate microsphere being distributed in the pores of the hyaluronic acid hydrogel. The calcium phosphate microsphere having a porosity suitable for delivery of the growth factor is positioned into the pores of the cross-linked hyaluronic acid hydrogel to complete the carrier.
Type:
Application
Filed:
March 30, 2012
Publication date:
July 2, 2015
Applicant:
BIOALPHA INC.
Inventors:
Jung Ju Kim, Su Hyun Jung, Hyun Seung Ryu, Jun Hyuk Seo
Abstract: Provided is a portable vacuum generator that can effectively save battery power of a vacuum pump for absorbing exudates from a suction head that is connected to a tube, and a medical suction device using the same.
Type:
Grant
Filed:
November 3, 2010
Date of Patent:
February 24, 2015
Assignee:
Bioalpha Inc.
Inventors:
Hyun Seung Ryu, Joon Pio Hong, Myong Chul Park, Jun Kyu Park
Abstract: Provided is a portable vacuum generator that can effectively save battery power of a vacuum pump for absorbing exudates from a suction head that is connected to a tube, and a medical suction device using the same.
Type:
Application
Filed:
November 3, 2010
Publication date:
October 11, 2012
Applicant:
BIOALPHA INC.
Inventors:
Hyun Seung Ryu, Joon Pio Hong, Myong Chul Park, Jun Kyu Park
Abstract: Disclosed herein is a method for preparing an aqueous solution of high-concentration calcium phosphate, the method comprising the steps of: preparing an acidic aqueous solution using an acidic chelating agent; and dissolving a calcium phosphate-based compound in the acidic aqueous solution, and then adding a pH-adjusting agent to the acidic aqueous solution to adjust the pH of the acidic aqueous solution. The disclosed aqueous solution does not form a precipitate after neutralization so that it can be used in various calcium-containing products, including foods, drugs, or quasi-drugs.
Type:
Grant
Filed:
July 19, 2011
Date of Patent:
October 2, 2012
Assignee:
Bioalpha Inc.
Inventors:
Hyun Seung Ryu, Mi Young Ryu, Jun Hyuk Seo, Gyu Dong Jang, Baek Il Kim
Abstract: Disclosed herein is a method for preparing an aqueous solution of high-concentration calcium phosphate, the method comprising the steps of: preparing an acidic aqueous solution using an acidic chelating agent; and dissolving a calcium phosphate-based compound in the acidic aqueous solution, and then adding a pH-adjusting agent to the acidic aqueous solution to adjust the pH of the acidic aqueous solution. The disclosed aqueous solution does not form a precipitate after neutralization so that it can be used in various calcium-containing products, including foods, drugs, or quasi-drugs.
Type:
Application
Filed:
July 19, 2011
Publication date:
July 19, 2012
Applicant:
BIOALPHA INC.
Inventors:
Hyun Seung RYU, Mi Young RYU, Jun Hyuk SEO, Gyu Dong JANG, Baek Il KIM