Abstract: A graft polymer obtainable by grafting a polymer substrate with a compound of formula (I), in which the groups R are the same or different and each is a straight or branched C.sub.1 -C.sub.4 alkyl group; X is an aryl group or a straight or branched C.sub.1 -C.sub.20 alkylene group, optionally containing one or more carbon-carbon double or triple bonds, ether linkages or aryl groups; the aryl groups being unsubstituted or substituted by one or more C.sub.1-4 alkyl groups; n is from 2 to 4; and A is a reactive group, is useful as a biocompatible material in contact lenses, biomedical devices and blood-containing devices. In a preferred embodiment A is a polymerizable group and the graft polymer is produced by radical initiated polymerization of the compound of formula (I) on the substrate which is initiated by a radical-forming group on the substrate.
Type:
Grant
Filed:
April 28, 1994
Date of Patent:
September 26, 1995
Assignee:
Biocompatibles Limited
Inventors:
Clement H. Bamford, Kadem G. Al-Lamee, Yiannakis Yianni, Martin C. Wiles, Trevor O. Glasbey
Abstract: A process of treating suitable synthetic polymers comprising the steps of (a) where appropriate, activating the surface to be treated, and, if necessary, providing spacer groups thereon; and (b) treating the surface with a compound of Formula (I), ##STR1## wherein Y' is an alkylene group optionally containing an aryl group, a poly(ethylene glycol) or a glycerol group; R may be the same or different and each is a straight or branched C.sub.1-4 alkyl group, n is from 1 to 4 and X is a group which reacts with functional groups of the polymer. Polymeric surfaces and materials thus produced and shaped articles containing such surfaces and materials.
Type:
Grant
Filed:
September 23, 1992
Date of Patent:
June 6, 1995
Assignee:
Biocompatibles Limited
Inventors:
Roderick W. J. Bowers, Stephen A. Jones, Peter W. Straford, Michael J. Driver
Abstract: A process for treating polymeric contact lenses comprising the steps of: (a) where necessary, activating the polymeric surface to be treated and (b) treating the surface with a compound of formula (I), wherein X is a group which reacts with the polymer surface; Y is straight or branched C.sub.1-6 alkylene; the groups R are the same or different and each is straight or branched C.sub.1-4 alkyl, and A.sup.- is a counterion.X--Y--CH.sub.2 N.sup..sym. R.sub.3 A.sup..crclbar.
Type:
Grant
Filed:
April 13, 1992
Date of Patent:
May 23, 1995
Assignee:
Biocompatibles Limited
Inventors:
Roderick W. J. Bowers, Stephen A. Jones, Peter W. Straford, Michael J. Driver