Abstract: The invention features a method of treating polyester material to generate functional carboxylic acid and amine groups. These functional groups can be used as sites for covalent bond formation to attach chemical or biological moieties. This bifunctionalized polyester polymer can be used in any medical application in which biocompatible polymers are used.
Type:
Grant
Filed:
January 27, 2003
Date of Patent:
May 2, 2006
Assignees:
University of Rhode Island, Beth Israel Deaconess Medical Center, BioMod Surfaces
Inventors:
Martin J. Bide, Matthew D. Phaneuf, William C. Quist, Donald J. Dempsey, Frank W. LoGerfo
Abstract: Provided is a biocompatible device which has been coated or sealed with a polyether or polyether/carbonate based urethane polymer that contains functional groups (e.g. carboxylic acid groups) which are capable of serving as anchor sites for protein binding.
Type:
Grant
Filed:
February 28, 2001
Date of Patent:
June 1, 2004
Assignees:
BioMod Surfaces, Beth Israel Deaconess Medical Center
Inventors:
Matthew D. Phaneuf, Donald J. Dempsey, William C. Quist, Frank W. Logerfo