Abstract: Provided herein are novel compounds based on xanthene, for example biarsenical compounds, which are useful as molecular probes. The compounds contain at least one isotope atom, such as a radioisotope atom. Methods for visualizing tetracysteine-tagged analyte molecules such as proteins using said compounds, methods for synthesizing said compounds, and methods for treating cancer or other hyperproliferative disorders using said compounds are also provided.
Type:
Grant
Filed:
November 15, 2011
Date of Patent:
October 7, 2014
Assignee:
Biopercept AB
Inventors:
Hans Eric Peter Strom, Samuel Par Simon Svensson
Abstract: Provided herein are novel compounds based on xanthene, for example biarsenical compounds, which are useful as molecular probes. The compounds contain at least one isotope atom, such as a radioisotope atom. Methods for visualizing tetracysteine-tagged analyte molecules such as proteins using said compounds, methods for synthesizing said compounds, and methods for treating cancer or other hyperproliferative disorders using said compounds are also provided.
Type:
Application
Filed:
November 15, 2011
Publication date:
December 5, 2013
Applicant:
BIOPERCEPT AB
Inventors:
Hans Eric Peter Strom, Samuel Par Simon Svensson