Abstract: The invention provides a handheld, manually operable fluid applicator, particularly suited to the needs of surgeons, for dispensing a multi-component fluid applicator, for example fibrin and thrombin components of a tissue adhesive. The sealant components undergo turbulent mixing in a mixing chamber which causes a sharp change of at least 60 degrees in the direction of flow of each sealant component, to provide effective mixing and a quality sealant product. The mixing chamber has an increased cross-sectional area over the combined areas of the component supply passages and the fluid flows are directly opposed to impinge on each other in the mixing chamber. The mixing chamber is incorporated in a novel one-piece flexible and resilient manifold. Dual nozzle spray applicators with poppet valves are also disclosed.
Type:
Grant
Filed:
March 9, 1998
Date of Patent:
May 16, 2000
Assignee:
Biosurgical Corporation
Inventors:
Gordon Howard Epstein, Alan Kirby Plyley, Russell James Redmond
Abstract: A process and apparatus for one-step preparation of fibrinogen adhesive by polyethylene glycol-mediated precipitation from plasma are disclosed. The methods and apparatus of the invention permit preparation of autologous fibrinogen adhesive composition from the patient during surgery, and can be applied generally to provide such compositions. Also disclosed are an apparatus and method for application of sealant comprising this fibrinogen adhesive composition.
Abstract: A medical fluid suctioning device for selectively applying varied levels of suction pressure at a device-tissue interface includes a direct "trumpet"-type control mechanism in conjunction with a "venturi"-type control. A valve manifold is adapted to couple a vent pathway and a suction pathway simultaneously to the vacuum conduit adapted for connection to a vacuum source. The amount of resistance to flow due to vacuum pressure is adjusted simultaneously in both the vent pathway and the suction pathway in order to achieve controlled, selected levels of suction. Similarly shaped valve apertures are provided in inverse and reciprocal orientation along an axis of motion of a valve manifold. The apertures translate across ports to the suction and venting pathways simultaneously to vary applied suction to those pathways inversely.
Abstract: A process and apparatus for one-step preparation of fibrinogen adhesive by polyethylene glycol-mediated precipitation from plasma are disclosed. The methods and apparatus of the invention permit preparation of autologous fibrinogen adhesive composition from the patient during surgery, and can be applied generally to provide such compositions. Also disclosed are an apparatus and method for application of sealant comprising this fibrinogen adhesive composition.