Abstract: Indole diterpene compounds named "radarin" have been isolated from the sclerotia of the fungus Aspergillus sulphureus. The radarins are effective for controlling Lepidopteran insects, and have the structures: ##STR1## wherein the compound formed when R is a hydroxyl group is designated radarin A and the compound formed when R is a hydrogen atom is designated radarin C; and ##STR2## wherein the compound formed when R is a hydrogen atom is designated radarin D and the compound formed when R is a hydroxyl group is designated radarin B.
Type:
Grant
Filed:
July 19, 1991
Date of Patent:
April 21, 1992
Assignees:
The United States of America as represented by the Secretary of Agriculture, Biotechnology Research & Development Corporation, University of Iowa Research Foundation
Inventors:
Jodi A. Laakso, Patrick F. Dowd, James B. Gloer, Donald T. Wicklow