Patents Assigned to BIOTRONIK Mess-und Therapiegeraete GmbH & Co. Ingenieurbuero Berlin
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Patent number: 6319249Abstract: The invention relates to an ablation system, including an ablation catheter with a plurality of ablation electrodes (34) and a neutral electrode (36), at least one energy source (22), switching elements (26, 28) for connecting the electrodes to the energy source (22) and control elements (16, 18, 20, 24) which are connected to the switching elements (26, 28). The control elements (16, 18, 20, 24) are configured in such a way that electrode pairs made up of both ablation electrodes (34) and an ablation electrode with a neutral electrode (36) can be connected to the energy source (22) in a predetermined sequence. The invention also relates to a method for controlling the electrodes of an ablation system of this type. According to said method, electrode pairs made up of both ablation electrodes (34) and an ablation electrode with a neutral electrode (36) are connected to the energy source (22) in a predetermined sequence.Type: GrantFiled: December 15, 1999Date of Patent: November 20, 2001Assignee: Biotronik Mess-und Therapiegeraete GmbH & Co. Ingenieurbuero BerlinInventor: Thomas Töllner
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Patent number: 6304781Abstract: Electrostimulator (2), comprising an interface for connecting a working electrode (2), as well as a pulse generator that is connected on the output side to the interface for transmitting electrical pulses to the working electrode (10), with a first measuring instrument (10) that is connected to the interface for measuring the electrical voltage present at the interface and/or the electrical current flowing over the interface, as well as an arithmetic unit, connected on the input side to the first measuring instrument, for computing an output signal reflecting the capacity of the working electrode in dependence on the current and/or voltage at the interface.Type: GrantFiled: October 30, 1998Date of Patent: October 16, 2001Assignee: Biotronik Mess- und Therapiegeräte GmbH & Co. Ingenieurbüero BerlinInventors: Ulrich Busch, Klaus Bartels
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Patent number: 6287332Abstract: An implantable, bioresorbable vessel wall support, in particular a coronary stent, comprises a combination of metal materials which dissolves in the human body without any harmful effects on the person that wears the implant. The combination of metal materials can be an alloy or a local galvanic element.Type: GrantFiled: June 25, 1999Date of Patent: September 11, 2001Assignee: Biotronik Mess- und Therapiegeraete GmbH & Co. Ingenieurbuero BerlinInventors: Armin Bolz, Thomas Popp
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Patent number: 6263243Abstract: A rate-adaptive pacemaker includes an impedance measuring device for measuring a waveform over time of the intracardial impedance over at least a predetermined portion of one cardiac cycle. An impedance processing device obtains an impedance value from the waveform. A rate determining device is connected downstream of the impedance processing device, and controlled by a sequence controller, determines the adaptive stimulation rate (HR) using the impedance value. The impedance processing device has an integrator stage for determining the time integral of the impedance waveform over the predetermined portion of the cardiac cycle as the primary impedance value.Type: GrantFiled: March 4, 1997Date of Patent: July 17, 2001Assignee: Biotronik Mess-und Therapiegeraete GmbH & Co. Ingenieurbuero BerlinInventor: Martin Lang
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Patent number: 6219581Abstract: A pacing electrode arrangement for stimulating the heart by means of an implantable pacemaker, comprising a first pacing electrode arranged in the vena cava superior and a second pacing electrode arranged in either the atrium, or a blood vessel near the heart other than the vena cava superior, or arranged at a distance from the heart, whereby the first and the second pacing electrode essentially enclose between them a predetermined, central region of the cardiac stimulus generating and conduction system.Type: GrantFiled: August 17, 1998Date of Patent: April 17, 2001Assignee: Biotronik Mess-und Therapiegeraete GmbH & Co. Ingenieurbuero BerlinInventors: Max Schaldach, Tran Thong
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Patent number: 6208901Abstract: In an apparatus for determining the AV transmission time or AV delay in the heart, the apparatus having a signal-sensor arrangement that is disposed in the heart and detects a natural cardiac action, further having at least one signal output and a processing unit that has at least one signal input that is connected to the signal output of the signal-sensor arrangement for calculating the natural AV transmission time based on the detected cardiac action, the signal-receiver arrangement includes a pressure-sensor arrangement that is disposed in the vicinity of the tricuspid valve in the right atrium and/or in the right ventricle for detecting intracardial pressure changes associated with the opening of the tricuspid valve.Type: GrantFiled: March 3, 1998Date of Patent: March 27, 2001Assignee: Biotronik Mess-und Therapiegeraete GmbH & Co. Ingenieurbuero BerlinInventor: Wolfgang Hartung
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Patent number: 6154674Abstract: A self-calibrating adaptive-rate cardiac pacemaker having a measuring and processing device for measuring the course over time of a physiological variable over a predetermined portion of a heart cycle and for obtaining a course parameter from the course over time, a stimulation parameter determining device downstream of the measuring and processing device and controlled by a sequence controller for determining a stimulation parameter value, in particular the adaptive stimulation rate, a body sensor connected to one input of the stimulation parameter determining device, for detecting an exertion variable, whose signal is used jointly with the course parameter to determine the stimulation parameter value, and a stimulator unit for generating and outputting stimulation pulses at the determined stimulation parameter value.Type: GrantFiled: January 29, 1999Date of Patent: November 28, 2000Assignee: Biotronik Mess-und Therapiegeraete GmbH & Co. Ingenieurbuero BerlinInventor: Jan H. Meier
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Patent number: 6115633Abstract: An implantable stimulator for treating arrhythmic function disturbances of a heart, comprising; a stimulation electrode for transmitting stimulation pulses to the heart, a pulse generator that is connected to the stimulation electrode for generating the stimulation pulses, a control unit connected to the pulse generator for controlling the pulse emissions, a hemodynamic sensor for controlling the pulse emission as a function of the cardiac pumping performance, the hemodynamic sensor including; two measuring electrodes located in or in electrical contact with a blood vessel, for measuring the blood impedance dependent on the blood throughput, a signal generator that generates an AC voltage for generating a test signal for impedance measurement, an electrical measuring device connected to the twvo measuring electrodes for determining the blood throughput as a function of the measured electrical signal; and a blood throughput signal-analysis unit for recognizing an arrhythmic cardiac finction disturbance using tType: GrantFiled: October 27, 1997Date of Patent: September 5, 2000Assignee: BIOTRONIK Mess-und Therapiegeraete GmbH & Co. Ingenieurbuero BerlinInventors: Volker Lang, Armin Bolz
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Patent number: 6064907Abstract: An arrangement for determining the heart rate (f.sub.RR) or the refractory ime of the cardiac tissue, particularly for detecting tachycardia or fibrillation, has an electrode (E) for sensing heart action signals (SIG), an input stage, connected to the electrode, for processing the heart action signals, a refractory member for ascertaining a refractory time value of the arrangement, in each case after a predetermined segment of a heart action signal, and a processing device, connected to the output of the input stage or of the refractory member, for determining the rate of the heart action signals, processed with blanking of the component that occurs during the refractory time, or for determining the refractory time value of the cardiac tissue.Type: GrantFiled: March 3, 1997Date of Patent: May 16, 2000Assignee: BIOTRONIK Mess--und Therapiegeraete GmbH & Co. Ingenieurbuero BerlinInventors: Tran Thong, Paul Wyborny, Dennis Digby, Nawzer Mehta, Max Schaldach
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Patent number: 6061592Abstract: A device for detecting pathological tachycardia, in particular for use with an implantable device for terminating tachycardias, having a classifican device, responding to at least one electrical signal derived from the heart, which if the classification criterion is met outputs an output signal indicating pathological tachycardia, having a plurality of classification devices for checking various classification criteria within one heart interval or on the basis of the evaluation of preceding heart intervals; a controllable counter that is connected to the outputs of the classification devices via first logic means; means for incrementing the counter state of the counter by a predetermined counting amount each time, if during a heart interval at least one of the primary classification signals appears; means for keeping the counter state constant or decrementing it by a predetermined counting amount, if no primary classification signal appears within the heart interval; and discriminator means, which output theType: GrantFiled: May 6, 1998Date of Patent: May 9, 2000Assignee: Biotronik Mess-und Therapiegeraete GmbH & Co. Ingenieurbuero BerlinInventor: Indra B. Nigam
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Patent number: 5968082Abstract: An implantable electrostimulation device and an electrode lead is devised ere for the electrical connection of the electrode lead, the top portion of the electrostimulation device has a securely installed connecting socket with radially inward pointing contact and holding devices on its inside wall, which are designed to engage with the electrode lead contact. The contact and holding means are formed by a plurality of cam and projection regions that are securely connected to the inside wall or formed out of this wall and are each at a predetermined angular distance in a circumferential direction of the socket. The electrode lead has a pin or annular contact for inserting into a connecting socket of the electro-stimulation device, which has radially outward pointing contact and holding units on its surface for engaging with the connecting socket.Type: GrantFiled: March 3, 1997Date of Patent: October 19, 1999Assignee: Biotronik Mess- und Therapiegeraete Gmbh & Co. Ingenieurbuero BerlinInventor: Horst Franz Heil
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Patent number: 5964794Abstract: An implantable stimulation electrode for use with an implantable tissue stimulator, in particular a pacemaker, defibrillator, bone or neurostimulator, having a metal substrate body and a coating, applied to the substrate body, for reducing the electrode impedance and/or increasing the tissue compatability, in which a ultrathin, specifically functionalized organic coating forming the entire outer surface of the stimulation electrode is provided, which adheres to the underlying surface as a consequence of irreversible physisorption or covalent chemical bonding.Type: GrantFiled: March 20, 1997Date of Patent: October 12, 1999Assignees: Biotronik Mess- und Therapiegeraete GmbH & Co. Ingenieurbuero Berlin, Max-Planck-Gensellschaft zur Foerderung der Wissenschaften e.V. BerlinInventors: Armin Bolz, Ronald Froehlch, Martin Stelzle, Johannes Schmitt, Anke Diederich, Thorsten Cassier, Roland Wagner
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Patent number: 5922015Abstract: An implantable device for at least temporary electrical contact with body tissue includes a stimulation electrode, a lead having a proximal end connected to a medical device and a distal end securely attached to the stimulation electrode and blocking means for holding the stimulation electrode in its position of contacting the body tissue, counter to a pulling force exerted by the lead. The blocking means is essentially rigid and is at least partially composed of a material that can be resorbed into body fluid. The blocking means includes a holder with a hole which is slipped or fitted onto a surgical thread thereby connecting the blocking means to the surgical thread.Type: GrantFiled: March 14, 1997Date of Patent: July 13, 1999Assignee: BIOTRONIK Mess- und Therapiegeraete GmbH & Co. Ingenieurbuero BerlinInventor: Max Schaldach
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Patent number: 5891048Abstract: A signal detector for detecting a biosignal with approximately known morpogy in a complex input signal (ECG), in particular for the detection of QRS complexes in an electrocardiogram. The detector has circuitry for detecting the maximum amplitude (PEAK) of the detected signal complex within a predetermined time window, with a threshold value discriminator, a detector parameter preselection circuit for determining an initial value for the detector parameter characterizing the detector sensitivity, which parameter determines the detector threshold value when responding to a detection signal in dependence on the maximum amplitude and a detector parameter timing circuit for adjusting a predetermined time dependence of the detector parameter and thus the detection threshold value.Type: GrantFiled: June 18, 1997Date of Patent: April 6, 1999Assignee: Biotronik Mess- und Therapiegeraete GmbH & Co. Ingenieurbuero BerlinInventors: Indra B. Nigam, Max Schaldach
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Patent number: 5876423Abstract: An implantable stimulator includes a depletable voltage source for supplying electrical energy. The voltage source has a terminal voltage which varies as a function of depletion of the voltage source. An output stage receives electrical energy from the voltage source and includes an arrangement for generating a stimulation voltage that is increased with respect to the terminal voltage of the voltage source and a stimulation energy storage device for storing the stimulation voltage. A control device receives operational energy from the voltage source and is operatively connected for controlling a stimulation operation of the stimulation energy storage device.Type: GrantFiled: June 4, 1997Date of Patent: March 2, 1999Assignee: Biotronik Mess- und Therapiegeraete GmbH & Co. Ingenieurbuero BerlinInventor: Hans-Juergen Braun
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Patent number: 5843134Abstract: A therapy device having at least one sensor for detecting a variable that n be measured on the body of a patient in the application of a predetermined therapy, and for outputting a corresponding measured value, an evaluating and control device that is connected to the output of the sensor, and a therapy device that is connected to the output of the evaluating and control device and is configured for realizing different therapies as a function of the association of the value of the measured variable with a predetermined value range, with the evaluating and control device having a range-limit memory, a comparator unit for associating the measured value of the variable with one of the value ranges, a therapy memory having at least two separately-addressable memory regions for storing at least two different values of the therapy-control variable in association with the values of the measured variable within an overlap zone between two value ranges, a past-history memory and past-history evaluation means for transType: GrantFiled: March 3, 1997Date of Patent: December 1, 1998Assignee: Biotronik Mess- und Therapiegeraete GmbH & Co. Ingenieurbuero BerlinInventors: Tran Thong, Dennis Digby, Max Schaldach
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Patent number: 5836889Abstract: A method of storing signals having a course over time in an implantable medical device, and/or transmitting the signals out of the device and out of the patient's body, with the course over time being detected in the device, particularly at predetermined time intervals with a constant sampling interval, and a sequence of signal samples being obtained therefrom, of which a partial quantity is stored and/or transmitted as the result of a selection made with a predetermined selection criterion, with the selection criterion being the first derivation of the course over time of the signals according to time, and with the selection being made such that the first derivation of the straight-line connection between an nth and the (n-1)th signal sample is determined and compared to the first derivation of the straight-line connection between the (n-1)th signal sample and the last-stored and/or last-transmitted signal sample, and the nth signal sample is then stored and/or transmitted as the new last signal sample exactType: GrantFiled: March 3, 1997Date of Patent: November 17, 1998Assignee: Biotronik Mess- und Therapiegeraete GmbH & Co. Ingenieurbuero BerlinInventors: Paul Wyborny, Indra Nigam, Max Schaldach
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Patent number: 5626624Abstract: An arrangement is provided for controlling a stimulation frequency of a pacemaker. The arrangement includes an atrial bipolar electrode system and a ventricular bipolar electrode system. A first electrode pair comprises an electrode from each of the atrial and ventricular bipolar electrode systems, with the electrodes of the first electrode pair being disposed intracardially in the atrium and ventricle, respectively. A pacemaker control unit generates stimulation pulses for stimulating the heart. A constant current source impresses a constant current to a second electrode pair, comprising at least one electrode from one of the atrial and ventricular bipolar electrode systems being disposed intracardially in one of the atrium and ventricle, for developing an electrical potential between the electrodes of the first electrode pair during predetermined cardiac phases.Type: GrantFiled: March 17, 1995Date of Patent: May 6, 1997Assignee: Biotronik Mess-und Therapiegeraete GmbH & Co. Ingenieurbuero BerlinInventors: Max Schaldach, Gustav Boheim
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Patent number: 5609611Abstract: A cardiac pacemaker system is provided which includes a stimulation electrode adapted for being anchored in the heart. An output capacitor is coupled to the stimulation electrode. A first circuit coupled to the output capacitor generates stimulation pulses. A second circuit coupled to the output capacitor generates an autoshort pulse following each stimulation pulse to reduce a residual charge of the output capacitor for eliminating an after potential following a stimulation pulse by the stimulation electrode. A third circuit coupled to the output capacitor acquires an evoked pulse of the heart from an electrical signal picked up by the stimulation electrode. The stimulation electrode includes a porous surface coating made of an inert material and has an active surface that is substantially larger than a surface of the basic geometric form of the stimulation electrode.Type: GrantFiled: March 17, 1995Date of Patent: March 11, 1997Assignee: Biotronik Mess-und Therapiegeraete GmbH & Co. Ingenieurbuero BerlinInventors: Armin Bolz, Max Schaldach
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Patent number: 5571158Abstract: A stimulation electrode having a porous surface coating whose active surface area is significantly greater than the surface area defined by the geometric shape of the electrode, wherein the surface coating comprises an inert material, i.e. a material having no or only a very slight oxidation tendency, wherein the material of the surface coating is formed from an inert element, an inert chemical compound and/or an inert alloy, and the active surface area, by virtue of its fractal-like geometry, is greater by a factor of at least one thousand than the surface area defined by the basic geometric shape of the electrode.Type: GrantFiled: June 23, 1994Date of Patent: November 5, 1996Assignee: Biotronik Mess- und Therapiegeraete GmbH & Co. Ingenieurbuero BerlinInventors: Armin Bolz, Max Schaldach