Patents Assigned to Blueprint Pharma S.R.L.
  • Heterodimeric peptide compounds displaying NGF activity and their use to treat neurodegenerative disorders
    Patent number: 8461110
    Abstract: Peptides having a structure characterized by the presence of two loops constrained in cyclic structure by the presence of covalent bonds between amino acid side chains, the amino acid sequences of the first and the second loop being substantially homologues to that of loop 1 (residues 29-38) and of loop 4 (residues 92-97) of NGF, respectively, displaying nerve growth factor (NGF) agonist or partial agonist activity.
    Type: Grant
    Filed: June 9, 2006
    Date of Patent: June 11, 2013
    Assignee: Blueprint Pharma S.R.L.
    Inventors: Luigi Vitagliano, Laura Zaccaro, Giancarlo Morelli, Enzo Martegani