Abstract: The present invention provides compositions and methods for treating cognitive impairment or dysfunction in a subject. In particular, the present invention provides a method for using a composition comprising an angiotensin-(1-7) receptor agonist to treat cognitive dysfunction or impairment that is due to a various clinical conditions including, but not limited to, those associated with increase in inflammation, cytokine production, increases in reactive oxygen species, changes in expression of brain inflammatory related genes and/or in the expression of genes involved in learning and memory within the central nervous system of a subject.

Abstract: The present invention provides a process for nitrating aromatic compounds without the need for a solid catalyst and/or any organic solvents and/or any other additives. A typical process includes combining or admixing a nitric acid and an anhydride compound under conditions sufficient to produce a reactive intermediate. The aromatic compound to be nitrated is then added to this reactive intermediate to produce a nitroaromatic compound. The nitroaromatic compound can be substituted with one or more, typically, one to three, and often one or two nitrate (—NO2) groups.

Abstract: The present invention provides a system and a method for detecting a neuromotor disorder or condition in a subject using an electronic device that comprises an input device. The method generally involves determining input device usage characteristics of the subject and comparing the result to a reference input device usage characteristic.

Abstract: Systems and methods for providing incentives for the public to travel during time windows and routes that help alleviate traffic congestion. The systems described herein include at least two components: a computer server software system that includes various algorithms and database sub-systems; and a mobile device application. Generally, a user may enter an origin, destination, and preferred time of travel for an intended trip into the mobile device application, which transmits the information to a remote server. The server computes a route for the trip and provides the user with available incentives for traveling the route at one or more departure time windows. The user's mobile device transmits GPS data to the server, which allows the server to verify whether the user has traveled the route during the specified time window. If so, the server then provides the incentive to the user via the user's mobile device or through email.

Abstract: Systems and methods for providing incentives for the public to travel during time windows and routes that help alleviate traffic congestion. The systems described herein include at least two components: a computer server software system that includes various algorithms and database sub-systems; and a mobile device application. Generally, a user may enter an origin, destination, and preferred time of travel for an intended trip into the mobile device application, which transmits the information to a remote server. The server computes a route for the trip and provides the user with available incentives for traveling the route at one or more departure time windows. The user's mobile device transmits GPS data to the server, which allows the server to verify whether the user has traveled the route during the specified time window. If so, the server then provides the incentive to the user via the user's mobile device or through email.

Abstract: The present invention provides a hologram which forms a light intensity distribution on a predetermined plane by using an incident light. The hologram includes a plurality of cells configured to control both a phase of a first polarized light component of the incident light and a phase of a second polarized light component. The plurality of cells are designed to form a portion in an overlap region in which a first light intensity distribution region formed on the predetermined plane by the first polarized light component and a second light intensity distribution region formed on the predetermined plane by the second polarized light component are superposed on each other. The phase of the first polarized light component is diffused in the portion formed in the overlap region.

Abstract: The present invention is directed to a multi-domain oligonucleotide ligand having multiple functions conferred by each of the domains. The ligand is bound to a solid phase matrix for use in both mRNA-affinity chromatography and as a priming matrix for generating matrix-bound cDNA from the mRNA bound to the matrix. The resultant cDNA was tested and found to function as a solid-phase template for PCR. This solid-phase template approach to PCR is demonstrated with oligo-d(T) paper. The functional domains are defined by polynucleotide sequences on the ligand to confer the different functions.

Abstract: A body-support frame comprising a horizontal table having two adjustable ces that can be moved along the main axis of the table for straddling a patient lying within the frame. Each brace is equipped with a swiveled clamp attached to an adjustable system of bracket-arms for the skeletal fixation and immobilization of the patient craniad and caudad to the area of interest. The frame contains orthogonal scales for orthogonal localization and measurements of the area of interest with reference to a chosen set of coordinates within the table. The frame also contains three adjustable radiographic calibration targets that are used for selectively setting a plane of reference in the proximity of the area of interest, so that the plane may be used for lining up the frame with radiographic imaging and radiation treatment apparatus.

Abstract: A hybrid gamma-ray semiconductor detector is used in combination with attenuating apertures of the kind used in emission computed tomography. The detector comprises a slab of semiconductor material partitioned into multiple cells individually connected to a multiplexer through indium-bump pressure welds for the sequential read-out of integrated pulses generated in each cell as a result of gamma-ray absorption events. The single output channel provided by the multiplexer permits the construction of semiconductor sensor cells approximately one millimeter in size for improved spatial resolution of the detector. The greater resolution of the detector makes it possible to narrow the distance between the image forming apertures and the detector's surface, thus minimizing overlapping of the gamma-ray radiation and the size of the overall apparatus.

Abstract: A method for recovering silver from a refractory manganese dioxide-silver ore. The ore is contacted with an effective amount of a culture of direct manganese-reducing Bacillus polymyxa bacteria. The ore-bacteria mixture is maintained at an approximately neutral pH until a sufficient amount of the manganese dioxide in the ore is reduced from Mn(IV) to Mn(II). The silver present in the ore is then recovered by conventional methods such as cyanide leaching.

Abstract: A compound having pesticidal activity and which has the following general formula: ##STR1## wherein: R.sub.1 is selected from hydrogen, C.sub.1-6 alkyl, halogen, C.sub.1-6 alkoxy, C.sub.2-6 alkoxycarbonyl, amino, nitro, CF.sub.3, and C.sub.1-5 -(alkyl and dialkyl)-amino;X is a divalent hydrocarbon radical having 1 to 8 carbon atoms in its backbone, which may be interrupted by 1 or 2 of O or S, and which may be substituted by 1 or more halogens, C.sub.1-4 alkyl groups or C.sub.1-4 alkoxy groups;Y is O, S, CH.sub.2, SO, or SO.sub.2 ;Z is O, S, CH.sub.2, SO, or SO.sub.2 ;R.sub.2 is selected from hydrogen, halogen, C.sub.1-6 alkyl, C.sub.1-6 alkoxy, C.sub.2-6 alkoxycarbonyl, amino, nitro, and CF.sub.3 ; andR.sub.3 is selected from hydrogen, halogen, C.sub.1-6 alkyl, C.sub.1-6 alkoxy, C.sub.2-6 alkoxycarbonyl, amino, nitro, C.sub.1-5 -(alkyl and dialkyl)amino, and CF.sub.3.

Abstract: The flue gas desulfurization process using a lime or limestone slurry scrubbing solution producing used liquor containing calcium sulfite or sulfate (typically gypsum). Precipitated particles are removed by feeding the used scrubbing liquor to an agitated crystallization zone to grow crystals and directing part of the used scrubbing liquor from that zone to a quiescent crystallization zone, in which particles are settled back into the agitated zone. An underflow stream from the agitated zone containing large crystals is combined with an overflow stream from the quiescent zone, which combined stream is clarified with the fines being returned to the scrubber and the large crystals being removed as a waste product. Apparatus for performing the above process in which the agitated and quiescent crystallization zones form part of a single crystallization vessel, and the two zones are separated by a baffle.